| SOSp Orian LLC | Anderson | 20–99 | ◐ LIKELY ACTIVE |
| SWStarchem -- Wellford Plant | Wellford | — | ◐ LIKELY ACTIVE |
| VPValley Proteins - Ward Facility | Ward | — | ◐ LIKELY ACTIVE |
Archer Daniels Midland | Kershaw | — | ◐ LIKELY ACTIVE |
| CFColumbia Farms:greenville | Greenville | — | ◐ LIKELY ACTIVE |
| PIPowersecure Incorporated | Newberry | — | ◐ LIKELY ACTIVE |
| RFRoseburg Forest Products Chester Engineered Wood Products Facility | Chester | — | ◐ LIKELY ACTIVE |
| AIApexical INC | Spartanburg | — | ◇ UNVERIFIED |
| BCBalchem CORP | Green Pond | — | ◇ UNVERIFIED |
| CFColumbia Farms, INC. | Monetta | — | ◇ UNVERIFIED |
| CFColumbia Farms:sunset Blvd | West Columbia | — | ◇ UNVERIFIED |
| HCHenkel Corporation | Greenville | — | ◇ UNVERIFIED |
| NFNestle Frozen Foods | Gaffney | — | ◇ UNVERIFIED |
| PFPerdue Farms Incorporated Dillon Sc Processing Plant | Dillon | — | ◇ UNVERIFIED |
Pilgrim's Pride Feed Mill | Sumter | — | ◇ UNVERIFIED |
| RSRaisio Staest U S INC | Summerville | — | ◇ UNVERIFIED |
Dblco LLC | Simpsonville | — | ◐ LIKELY ACTIVE |
Simgov Solutions, LLC | North Charleston | — | ◐ LIKELY ACTIVE |
| GEGreen Energy Biofuel | Warrenville | — | ◇ UNVERIFIED |
| AFAmick Farms: Monetta | Monetta | — | ◐ LIKELY ACTIVE |
| DPDiamond Pet Food Processors of South Carolina LLC | Gaston | 100–499 | ◐ LIKELY ACTIVE |
| DPDoane Pet Care CO | Orangeburg | — | ◐ LIKELY ACTIVE |
| GEGreen Energy BioFuel Winnsboro | Winnsboro | 1–19 | ◐ LIKELY ACTIVE |
| GPGreenwood Packing Plant - Eddy Carolina Pride LLC | Greenwood | — | ◐ LIKELY ACTIVE |
| HOHouse of Raeford | Greenville | — | ◐ LIKELY ACTIVE |
| HOHouse of Raeford Farms INC | West Columbia | — | ◐ LIKELY ACTIVE |
| KMKgm Manufacturing LLC | Moore | — | ◐ LIKELY ACTIVE |
| MFMccall Farms | Effingham | — | ◐ LIKELY ACTIVE |
| MFMccall Farms INC | Effingham | — | ▲ REPORTED CLOSED |
| PPPalmetto Pigeon Plant | Sumter | — | ◐ LIKELY ACTIVE |
| PFPrestage Farms | Cassatt | — | ◐ LIKELY ACTIVE |
| SRSandy Run Roasting Plant | Gaston | 100–499 | ◐ LIKELY ACTIVE |
| CPChef's Pantry, LLC Easley Wastewater Lagoon Closure | Easley | — | ◐ LIKELY ACTIVE |
| DPDiana Petfood (former Spf-usa) | Hodges | — | ◐ LIKELY ACTIVE |
| EMEd&f Man Feed Ingredients LLC | Gaffney | — | ◐ LIKELY ACTIVE |
| NSNational Starch LLC | North Charleston | — | ◐ LIKELY ACTIVE |
| UIUnichem INC | Greenville | — | ◐ LIKELY ACTIVE |
| AFAmick Farms Feed Mill | Monetta | — | ◇ UNVERIFIED |
Archer Daniels Midland Company (adm) | Estill | — | ◇ UNVERIFIED |
| AAAvara Aiken Pharmaceutical Services INC | Aiken | — | ◇ UNVERIFIED |
| BBBaker & Baker | Spartanburg | — | ◇ UNVERIFIED |
| CSCarolina Starches | North Charleston | — | ◇ UNVERIFIED |
| CSCircle S Ranch Feedmill | Richburg | — | ◇ UNVERIFIED |
| EBEcogy Biofuels LLC | Estill | — | ◇ UNVERIFIED |
| HOHartsville Oil Mill | Darlington | — | ◇ UNVERIFIED |
| IBInterstate Brands CORP - Closed | Florence | — | ◇ UNVERIFIED |
| LCLaurens Container International Paper | Laurens | — | ◇ UNVERIFIED |
| LCLowcountry Creamery, LLC | Bowman | — | ◇ UNVERIFIED |
| NJNash Johnson & Sons Farms INC | Leesville | — | ◇ UNVERIFIED |
| PFPepperidge Farms Incorporated | Aiken | — | ◇ UNVERIFIED |