| Scissors, Nasal | Federal registry | 1 |
| Scissors, Ophthalmic | Federal registry | 1 |
| Scissors, Orthopedic, Surgical | Federal registry | 1 |
| Scissors, Umbilical | Federal registry | 1 |
| Scissors, Wire Cutting, Ent, Sterile | Federal registry | 1 |
| Scoop | Federal registry | 1 |
| Screw, Oral | Federal registry | 1 |
| Screw, Tonsil | Federal registry | 1 |
| Searcher, Mastoid | Federal registry | 1 |
| Sensor, Blood-Gas, In-Line, Cardiopulmonary Bypass | Federal registry | 1 |
| Sensor, Glucose, Implanted, Non-Adjunctive Use | Federal registry | 1 |
| Set, Administration, Intravascular | Federal registry | 1 |
| Set, Hollow Mill | Federal registry | 1 |
| Set, Laryngeal Injection | Federal registry | 1 |
| Set, Lens, Trial, Ophthalmic | Federal registry | 1 |
| Sheet, Burn | Federal registry | 1 |
| Shield, Eye, Radiological | Federal registry | 1 |
| Shield, Nipple | Federal registry | 1 |
| Shunt, Central Nervous System And Components | Federal registry | 1 |
| Sizer, Heart-Valve, Prosthesis | Federal registry | 1 |
| Skid, Bone | Federal registry | 1 |
| Skin Prep Tray | Federal registry | 1 |
| Sling, Arm | Federal registry | 1 |
| Snare, Ear | Federal registry | 1 |
| Snare, Enucleating | Federal registry | 1 |
| Snare, Non-Electrical | Federal registry | 1 |
| Snare, Surgical | Federal registry | 1 |
| Snare, Tonsil | Federal registry | 1 |
| Solution, Formalin-Alcohol-Acetic Acid | Federal registry | 1 |
| Solution, Lugol'S | Federal registry | 1 |
| Sound, Metal, Interconnected | Federal registry | 1 |
| Sound, Urethral, Metal Or Plastic | Federal registry | 1 |
| Sound, Uterine | Federal registry | 1 |
| Source, Carrier, Fiberoptic Light | Federal registry | 1 |
| Spatula, Ophthalmic | Federal registry | 1 |
| Spatula, Orthopedic | Federal registry | 1 |
| Spatula, Surgical, General & Plastic Surgery | Federal registry | 1 |
| Spectacle, Operating (Loupe), Ophthalmic | Federal registry | 1 |
| Specula Accessories | Federal registry | 1 |
| Specula, Ophthalmic | Federal registry | 1 |
| Speculum, Ent | Federal registry | 1 |
| Speculum, Illuminated | Federal registry | 1 |
| Speculum, Non-Illuminated | Federal registry | 1 |
| Speculum, Rectal | Federal registry | 1 |
| Speculum, Vaginal, Metal | Federal registry | 1 |
| Speculum, Vaginal, Nonmetal | Federal registry | 1 |
| Spirometer, Therapeutic (Incentive) | Federal registry | 1 |
| Splint, Denis Brown | Federal registry | 1 |
| Splint, Nasal | Federal registry | 1 |
| Splint, Traction | Federal registry | 1 |