| Shield, Eye, Radiological | Federal registry | 1 |
| Shield, Nipple | Federal registry | 1 |
| Shunt, Central Nervous System And Components | Federal registry | 1 |
| Sizer, Heart-Valve, Prosthesis | Federal registry | 1 |
| Skid, Bone | Federal registry | 1 |
| Skin Prep Tray | Federal registry | 1 |
| Sling, Arm | Federal registry | 1 |
| Snare, Ear | Federal registry | 1 |
| Snare, Enucleating | Federal registry | 1 |
| Snare, Non-Electrical | Federal registry | 1 |
| Snare, Surgical | Federal registry | 1 |
| Snare, Tonsil | Federal registry | 1 |
| Software For Diagnosis/Treatment | Federal registry | 1 |
| Solution, Formalin-Alcohol-Acetic Acid | Federal registry | 1 |
| Solution, Lugol'S | Federal registry | 1 |
| Sound, Metal, Interconnected | Federal registry | 1 |
| Sound, Urethral, Metal Or Plastic | Federal registry | 1 |
| Sound, Uterine | Federal registry | 1 |
| Source, Carrier, Fiberoptic Light | Federal registry | 1 |
| Spatula, Ophthalmic | Federal registry | 1 |
| Spatula, Orthopedic | Federal registry | 1 |
| Spatula, Surgical, General & Plastic Surgery | Federal registry | 1 |
| Spectacle, Operating (Loupe), Ophthalmic | Federal registry | 1 |
| Specula Accessories | Federal registry | 1 |
| Specula, Ophthalmic | Federal registry | 1 |
| Speculum, Ent | Federal registry | 1 |
| Speculum, Illuminated | Federal registry | 1 |
| Speculum, Non-Illuminated | Federal registry | 1 |
| Speculum, Rectal | Federal registry | 1 |
| Speculum, Vaginal, Metal | Federal registry | 1 |
| Speculum, Vaginal, Nonmetal | Federal registry | 1 |
| Spinal Vertebral Body Replacement Device | Federal registry | 1 |
| Spirometer, Therapeutic (Incentive) | Federal registry | 1 |
| Splint, Nasal | Federal registry | 1 |
| Splint, Traction | Federal registry | 1 |
| Spoon, Ear | Federal registry | 1 |
| Spoon, Ophthalmic | Federal registry | 1 |
| Spreader, Pulp Canal Filling Material, Endodontic | Federal registry | 1 |
| Spud, Ophthalmic | Federal registry | 1 |
| Stabilizer, Heart | Federal registry | 1 |
| Staple, Removable (Skin) | Federal registry | 1 |
| Starter, Bone Screw | Federal registry | 1 |
| Stethoscope, Fetal | Federal registry | 1 |
| Stethoscope Head | Federal registry | 1 |
| Stethoscope, Manual | Federal registry | 1 |
| Stimulator, Caloric-Air | Federal registry | 1 |
| Stimulator, Nerve | Federal registry | 1 |
| Stimulator, Nerve, Battery-Powered | Federal registry | 1 |
| Stimulator, Nerve, Transcutaneous, For Pain Relief | Federal registry | 1 |
| Stocking, Medical Support (For General Medical Purposes) | Federal registry | 1 |