| Shell, Scleral | Federal registry | 1 |
| Shield, Eye, Radiological | Federal registry | 1 |
| Shield, Gonadal | Federal registry | 1 |
| Shoe, Cast | Federal registry | 1 |
| Shoulder Prosthesis, Reverse Configuration | Federal registry | 1 |
| Single Lumen Ecmo Cannula | Federal registry | 1 |
| Single (Specified) Analyte Controls (Assayed And Unassayed) | Federal registry | 1 |
| Sling, Arm | Federal registry | 1 |
| Speculum, Ent | Federal registry | 1 |
| Spinal Vertebral Body Replacement Device | Federal registry | 1 |
| Spinous Process Plate | Federal registry | 1 |
| Spirometer, Therapeutic (Incentive) | Federal registry | 1 |
| Splint, Clavicle | Federal registry | 1 |
| Splint, Hand, And Components | Federal registry | 1 |
| Stabilizer, Heart | Federal registry | 1 |
| Stains, Dye Solution | Federal registry | 1 |
| Staple, Implantable | Federal registry | 1 |
| Starter, Bone Screw | Federal registry | 1 |
| Stent, Carotid | Federal registry | 1 |
| Stent, Iliac | Federal registry | 1 |
| Stent, Iliac Vein | Federal registry | 1 |
| Stents, Drains And Dilators For The Biliary Ducts | Federal registry | 1 |
| Stent, Superficial Femoral Artery | Federal registry | 1 |
| Stent, Vaginal | Federal registry | 1 |
| Sterilant, Medical Devices | Federal registry | 1 |
| Stimulator, Autonomic Nerve, Implanted For Stroke Rehabilitation | Federal registry | 1 |
| Stimulator, Carotid Sinus Nerve | Federal registry | 1 |
| Stimulator, Nerve, Battery-Powered | Federal registry | 1 |
| Stimulator, Nerve, Peripheral, Electric | Federal registry | 1 |
| Stimulator, Peripheral Nerve, Non-Implanted, For Urinary Incontinence | Federal registry | 1 |
| Strip, Test, Reagent, Residuals For Dialysate, Disinfectant | Federal registry | 1 |
| Stylet For Catheter, Gastro-Urology | Federal registry | 1 |
| Sucker, Cardiotomy Return, Cardiopulmonary Bypass | Federal registry | 1 |
| Support, Breathing Tube | Federal registry | 1 |
| Surgical Device, For Cutting, Coagulation, And/Or Ablation Of Tissue, Including Cardiac Tissue | Federal registry | 1 |
| Syringe, Piston | Federal registry | 1 |
| System, Applicator, Radionuclide, Manual | Federal registry | 1 |
| System, Dialysate Delivery, Single Patient | Federal registry | 1 |
| System, Facet Screw Spinal Device | Federal registry | 1 |
| System, Gastrointestinal Motility (Electrical) | Federal registry | 1 |
| System, Imaging, Pulsed Echo, Ultrasonic | Federal registry | 1 |
| System, Measurement, Blood-Pressure, Non-Invasive | Federal registry | 1 |
| System, Multipurpose For In Vitro Coagulation Studies | Federal registry | 1 |
| System, Network And Communication, Physiological Monitors | Federal registry | 1 |
| System, Skin Closure | Federal registry | 1 |
| System, Suspension, Cell Culture | Federal registry | 1 |
| System, Test, Breath Nitric Oxide | Federal registry | 1 |
| System, Test, Osteocalcin | Federal registry | 1 |
| System, Test, Vitamin D | Federal registry | 1 |
| System, Thermal Regulating | Federal registry | 1 |
