| Scissors, Surgical Tissue, Dental | Federal registry | 1 |
| Scissors, Wire Cutting, Ent, Non-Sterile | Federal registry | 1 |
| Scoop | Federal registry | 1 |
| Screen, Leaded, Operator Radiation Protector | Federal registry | 1 |
| Screw, Oral | Federal registry | 1 |
| Screw, Tonsil | Federal registry | 1 |
| Sealant, Dural | Federal registry | 1 |
| Securement Wound Dressing For Reduction Of Infection | Federal registry | 1 |
| Set, Administration, Intravascular | Federal registry | 1 |
| Set, Anesthesia, Obstetric | Federal registry | 1 |
| Set, I.V. Fluid Transfer | Federal registry | 1 |
| Shield, Eye, Radiological | Federal registry | 1 |
| Shunt, Central Nervous System And Components | Federal registry | 1 |
| Single (Specified) Analyte Controls (Assayed And Unassayed) | Federal registry | 1 |
| Single Use Only Blood Lancet With An Integral Sharps Injury Prevention Feature | Federal registry | 1 |
| Skid, Bone | Federal registry | 1 |
| Sling, Arm | Federal registry | 1 |
| Snare, Ear | Federal registry | 1 |
| Snare, Nasal | Federal registry | 1 |
| Snare, Tonsil | Federal registry | 1 |
| Sound, Urethral, Metal Or Plastic | Federal registry | 1 |
| Sound, Uterine | Federal registry | 1 |
| Source, Carrier, Fiberoptic Light | Federal registry | 1 |
| Spatula, Ophthalmic | Federal registry | 1 |
| Spatula, Surgical, General & Plastic Surgery | Federal registry | 1 |
| Specimen/Tissue, Identification Orientation | Federal registry | 1 |
| Specula Accessories | Federal registry | 1 |
| Specula, Ophthalmic | Federal registry | 1 |
| Speculum, Ent | Federal registry | 1 |
| Speculum, Non-Illuminated | Federal registry | 1 |
| Speculum, Vaginal, Nonmetal | Federal registry | 1 |
| Spinal Vertebral Body Replacement Device - Cervical | Federal registry | 1 |
| Spinous Process Plate | Federal registry | 1 |
| Splint, Clavicle | Federal registry | 1 |
| Splint, Extremity, Non-Inflatable, External, Non-Sterile | Federal registry | 1 |
| Splint, Intranasal Septal | Federal registry | 1 |
| Sponge, Ophthalmic | Federal registry | 1 |
| Spoon, Ear | Federal registry | 1 |
| Spreader, Pulp Canal Filling Material, Endodontic | Federal registry | 1 |
| Stainless Steel Instrument, Shunt System Implantation | Federal registry | 1 |
| Stain, Reticulocyte | Federal registry | 1 |
| Stand, Instrument, Ac-Powered, Ophthalmic | Federal registry | 1 |
| Staple, Fixation, Bone | Federal registry | 1 |
| Stents, Drains And Dilators For The Biliary Ducts | Federal registry | 1 |
| Stethoscope, Fetal | Federal registry | 1 |
| Stethoscope, Manual | Federal registry | 1 |
| Stimulator, Bone Growth, Non-Invasive | Federal registry | 1 |
| Stimulator, Invasive Bone Growth | Federal registry | 1 |
| Stimulator, Nerve | Federal registry | 1 |
| Stimulator, Nerve, Peripheral, Electric | Federal registry | 1 |