Altium Packaging - Breinigsville | Breinigsville, PA | Plastics and Rubber Products Manufacturing326160 | 20–99 | ◐ LIKELY ACTIVE |
| ARAmcor Rigid Packaging | Allentown, PA | Plastics and Rubber Products Manufacturing326160 | 100–499 | ◐ LIKELY ACTIVE |
| AAAmerican Atelier Inc. | Allentown, PA | Wood Product Manufacturing321211 | 20–99 | ◐ LIKELY ACTIVE |
| ACAmerican Craft Brewery (Samual Adams PA Brewery) | Breinigsville, PA | Beverage and Tobacco Product Manufacturing312120 | 500+ | ◐ LIKELY ACTIVE |
| ALAmericold Logistics | Fogelsville, PA | — | — | ◐ LIKELY ACTIVE |
| ALAmericold Logistics, LLC | Allentown, PA | — | — | ◐ LIKELY ACTIVE |
| AVAmore Vineyards & Winery | Nazareth, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| AAnchor | Northampton, PA | Fabricated Metal Product Manufacturing332710 | 20–99 | ◐ LIKELY ACTIVE |
| AWAnmina Winery & Vineyards | Lansford, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| AApollo | Bethlehem, PA | Fabricated Metal Product Manufacturing332813 | 20–99 | ◐ LIKELY ACTIVE |
| ASApplied Separations, Inc. | Allentown, PA | Computer and Electronic Product Manufacturing334516 | 1–19 | ◐ LIKELY ACTIVE |
| ATAP Thermoforming | Palmerton, PA | Plastics and Rubber Products Manufacturing326199 | 20–99 | ◐ LIKELY ACTIVE |
| AFArctic Foods USA, LLC | Washington, NJ | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| AIATAS International Inc. | Allentown, PA | Fabricated Metal Product Manufacturing332323 | 20–99 | ◐ LIKELY ACTIVE |
| APAxium Packaging : Bethlehem | Bethlehem, PA | Plastics and Rubber Products Manufacturing326160 | 20–99 | ◐ LIKELY ACTIVE |
| BBBakerly Barn, LLC-Easton Facility | Easton, PA | Food Manufacturing311812 | 100–499 | ◐ LIKELY ACTIVE |
| BHBath HMA Plant | Bath, PA | Petroleum and Coal Products Manufacturing324121 | 1–19 | ◐ LIKELY ACTIVE |
| BBB. Braun Medical Inc. | Allentown, PA | Miscellaneous Manufacturing339112 | 500+ | ◐ LIKELY ACTIVE |
| BBB. Braun US Device Manufacturing LLC | Allentown, PA | — | — | ◐ LIKELY ACTIVE |
| BZBefesa Zinc US Inc. Palmerton | Palmerton, PA | Primary Metal Manufacturing331492 | 20–99 | ◐ LIKELY ACTIVE |
| BPBehr Paint Company Allentown MFG | Allentown, PA | Chemical Manufacturing325510 | 20–99 | ◐ LIKELY ACTIVE |
| BBBethel Brewing and Spirits, INC. | Mount Bethel, PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| BBBethlehem Branch 67 | Bethlehem, PA | Chemical Manufacturing325120 | 1–19 | ◐ LIKELY ACTIVE |
| BFBethlehem Facility | Bethlehem, PA | Chemical Manufacturing325412 | 100–499 | ◐ LIKELY ACTIVE |
| BPBethlehem PA | Bethlehem, PA | Food Manufacturing311942 | 20–99 | ◐ LIKELY ACTIVE |
| BSBethlehem Site | Bethlehem, PA | Plastics and Rubber Products Manufacturing326160 | 100–499 | ◐ LIKELY ACTIVE |
| BSBeth Steel Corporation | Bethlehem, PA | Primary Metal Manufacturing331110 | — | ◐ LIKELY ACTIVE |
| B4Bihler 4-Slide | Phillipsburg, NJ | Fabricated Metal Product Manufacturing332999 | 1–19 | ◐ LIKELY ACTIVE |
| BBilby | Hackettstown, NJ | Food Manufacturing311919 | 20–99 | ◐ LIKELY ACTIVE |
| BWBinah Winery | Allentown, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BDBlack & Decker (u.s.) INC. | Allentown, PA | Furniture and Related Product Manufacturing337127 | — | ◐ LIKELY ACTIVE |
| BFBlack Flag Distilling CO. | Coplay, PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| BWBlackledge Winery, LLC | Center Valley, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BRBlack River Vineyards | Bethlehem, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BMBlue Mountain Vineyards & Cellars LTD. | New Tripoli, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BRBlue Ridge Lumber HC | Hackettstown, NJ | Wood Product Manufacturing321113 | 1–19 | ◐ LIKELY ACTIVE |
| BSBlue Steel Vodka, LLC | Allentown, PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| BBBlueTriton Brands - Allentown East Facility | Breinigsville, PA | Beverage and Tobacco Product Manufacturing312112 | 100–499 | ◐ LIKELY ACTIVE |
| BMB & M Provisions Co. | Allentown, PA | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| BBBrandt Box & Paper CO INC | Columbia, NJ | Paper Manufacturing322211 | — | ◐ LIKELY ACTIVE |
| BBreinigsville | Breinigsville, PA | Machinery Manufacturing333242 | 20–99 | ◐ LIKELY ACTIVE |
| BLBritech LLC | Allentown, PA | Computer and Electronic Product Manufacturing334419 | 20–99 | ◐ LIKELY ACTIVE |
| BBrookdale | Alburtis, PA | Electrical Equipment, Appliance & Component Manufacturing335931 | 100–499 | ◐ LIKELY ACTIVE |
| BHBrook Hollow Winery | Columbia, NJ | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BFBulldog Fire Apparatus | Nesquehoning, PA | Transportation Equipment Manufacturing336211 | 20–99 | ◐ LIKELY ACTIVE |
| CLCAPS Lehigh Valley | Allentown, PA | Chemical Manufacturing325412 | 100–499 | ◐ LIKELY ACTIVE |
| CCCardinal CT | Easton, PA | Nonmetallic Mineral Product Manufacturing327215 | 20–99 | ◐ LIKELY ACTIVE |
| CLCCNA L.V. Syrup Plant | Allentown, PA | Beverage and Tobacco Product Manufacturing312111 | 100–499 | ◐ LIKELY ACTIVE |
| CAChan and Chan USA, LLC | Bethlehem, PA | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| CCChristmas City Spirits, LLC | Bethlehem, PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |