| SSSpectrum Signs and Lettering LLC | Bangor, PA | Miscellaneous Manufacturing339950 | — | ◐ LIKELY ACTIVE |
| SHStaver Hydraulics - Allentown | Allentown, PA | Fabricated Metal Product Manufacturing332912 | 1–19 | ◐ LIKELY ACTIVE |
| SHStaver Hydraulics - Bath | Bath, PA | Miscellaneous Manufacturing339991 | 1–19 | ◐ LIKELY ACTIVE |
| SWStonehenge Winery & Vineyard | Mount Bethel, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| STStrategic Technologies and Research Manufacturing LLC | Easton, PA | Machinery Manufacturing333248 | — | ◐ LIKELY ACTIVE |
| SASunOpta Allentown | Allentown, PA | Food Manufacturing311514 | 100–499 | ◐ LIKELY ACTIVE |
| SFSunOpta Foods, Inc. | Allentown, PA | — | — | ◐ LIKELY ACTIVE |
| SHSupplies Hotline Corporation | Bethlehem, PA | Miscellaneous Manufacturing339940 | — | ◐ LIKELY ACTIVE |
| SESupport Equipment Manufacturing LLC | Easton, PA | Fabricated Metal Product Manufacturing332710 | — | ◐ LIKELY ACTIVE |
| TPTechnical Process & Engineering Inc | Lehighton, PA | Fabricated Metal Product Manufacturing332710 | 20–99 | ◐ LIKELY ACTIVE |
| TCThe Colony Meadery, LLC | Easton, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TFThe Flying Meatballs LLC | Easton, PA | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| TMThe Mad Hatter Winery | Jim Thorpe, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TLThis Life Forever | Allentown, PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| TLThis Life Forever INC | Lansford, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TLThree Little Birds Distillery LLC | Macungie, PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| TITKG Industrial Ceramics | Allentown, PA | Nonmetallic Mineral Product Manufacturing327120 | 20–99 | ◐ LIKELY ACTIVE |
| TVTolino Vineyards, LLC | Bangor, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
Tower Products, Easton | Easton, PA | Chemical Manufacturing325199 | 20–99 | ◐ LIKELY ACTIVE |
| TPTrexlertown, Pa | Trexlertown, PA | Paper Manufacturing322211 | 20–99 | ◐ LIKELY ACTIVE |
| TGTrinity Glass - Pennsylvania | Breinigsville, PA | Wood Product Manufacturing321911 | 100–499 | ◐ LIKELY ACTIVE |
| TSTriple Sun Spirits Company | Emmaus, PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| TITrius Inc Bethlehem PA | Bethlehem, PA | Machinery Manufacturing333120 | 20–99 | ◐ LIKELY ACTIVE |
| UCUngerer & Company | Bethlehem, PA | Food Manufacturing311942 | 100–499 | ◐ LIKELY ACTIVE |
| UUnion | Allentown, PA | Chemical Manufacturing325412 | 1–19 | ◐ LIKELY ACTIVE |
| USUnited States Cold Storage | Bethlehem, PA | — | — | ◐ LIKELY ACTIVE |
| UIUniversal Industrial Gases | Bethlehem, PA | Chemical Manufacturing325120 | 100–499 | ◐ LIKELY ACTIVE |
| UMUS Modular LLC | Fogelsville, PA | Fabricated Metal Product Manufacturing332311 | 20–99 | ◐ LIKELY ACTIVE |
| UPUS PL Allentown NPPC | Allentown, PA | Food Manufacturing311111 | 500+ | ◐ LIKELY ACTIVE |
| VVVacchiano Vineyards | Washington, NJ | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| VViking | Nesquehoning, PA | Machinery Manufacturing333913 | 1–19 | ◐ LIKELY ACTIVE |
| VSVultee Street | Allentown, PA | Machinery Manufacturing333295 | 20–99 | ◐ LIKELY ACTIVE |
| VWVynecrest Winery | Breinigsville, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WSWarDog Spirits | Bethlehem, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WVWeathered Vineyards, LLC | New Tripoli, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WCWeatherly Casting & Machine Co., LLC | Weatherly, PA | Machinery Manufacturing333511 | 20–99 | ◐ LIKELY ACTIVE |
| WHWescoville HMA Plant | Allentown, PA | Petroleum and Coal Products Manufacturing324121 | 1–19 | ◐ LIKELY ACTIVE |
| WEWild Elder Wine and Cider CO | Lehighton, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WHWind Hill Winery | Coopersburg, PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| SSSantana90s Solution LLC | Allentown, PA | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| LWLight Weight Manufacturing | Allentown, PA | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| WBWeyerbacher Brewing, INC. | Easton, PA | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| 6G6642 Grant Way Bldg Expansion | Allentown, PA | Textile Mills313310 | — | ◇ UNVERIFIED |
| AMAccu Machining Center, INC. | Easton, PA | Fabricated Metal Product Manufacturing332710 | — | ◇ UNVERIFIED |
| APAdvanced Personalization Solutions LLC | Allentown, PA | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| AVAdvanced Valve Design, INC. | Whitehall, PA | Machinery Manufacturing333999 | — | ◇ UNVERIFIED |
| AFAetna Felt CORP. | Allentown, PA | Textile Mills313230 | — | ◇ UNVERIFIED |
| APAir Products and Chemicals, INC. | Allentown, PA | Chemical Manufacturing325998 | — | ◇ UNVERIFIED |
| AMAlbertini Manufacturing and Supply INC | Lansford, PA | Machinery Manufacturing333912 | — | ◇ UNVERIFIED |
| ASAllentown Steel Fabricating Co., INC. | Catasauqua, PA | Fabricated Metal Product Manufacturing332999 | — | ◇ UNVERIFIED |