| BPBuffalo Pumps Division | North Tonawanda, NY | Machinery Manufacturing333911 | — | ◐ LIKELY ACTIVE |
| CGCamellia General Provision CO INC | Buffalo, NY | Food Manufacturing311611 | — | ◐ LIKELY ACTIVE |
| CTCarleton Technologies | Orchard Park, NY | Fabricated Metal Product Manufacturing332912 | — | ◐ LIKELY ACTIVE |
| CJC J Krantz INC Organic Recycling Center | East Amherst, NY | Chemical Manufacturing325314 | — | ◐ LIKELY ACTIVE |
| CCClarksburg Cider | Lancaster, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CLCompu-mail, LLC | Grand Island, NY | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| CLCounty Line Stone - Akron Quarry | Akron, NY | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| CBCPEG Buffalo LLC. - Annex | Tonawanda, NY | Fabricated Metal Product Manufacturing332313 | 1–19 | ◐ LIKELY ACTIVE |
| CMCrescent Marketing (dba Crescent Mfg ) | Eden, NY | Chemical Manufacturing325612 | — | ◐ LIKELY ACTIVE |
| DIDeckorators INC | Buffalo, NY | Plastics and Rubber Products Manufacturing326199 | — | ◐ LIKELY ACTIVE |
| DCDiversified Control INC | Orchard Park, NY | Fabricated Metal Product Manufacturing332322 | 20–99 | ◐ LIKELY ACTIVE |
| DMDiversified Manufacturing Acquisition, Inc. | Lockport, NY | Fabricated Metal Product Manufacturing332710 | 20–99 | ◐ LIKELY ACTIVE |
| DPDual Print and Mail LLC | Cheektowaga, NY | Printing and Related Support Activities323110 | — | ◐ LIKELY ACTIVE |
| ECExolon-esk CO | Tonawanda, NY | Nonmetallic Mineral Product Manufacturing327910 | — | ◐ LIKELY ACTIVE |
| FGFord Gum & Machine CO INC | Akron, NY | Food Manufacturing311340 | — | ◐ LIKELY ACTIVE |
| FWFrank Wardynski & Sons, INC. | Buffalo, NY | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| GAGlobal Abrasive Products | Lockport, NY | Nonmetallic Mineral Product Manufacturing327910 | — | ◐ LIKELY ACTIVE |
| GAGlobal Abrasive Products | Lockport, NY | Nonmetallic Mineral Product Manufacturing327910 | — | ◐ LIKELY ACTIVE |
| GSGold Star Feed and Grain, LLC Springville NY | Springville, NY | Food Manufacturing311111 | 20–99 | ◐ LIKELY ACTIVE |
| GMGreenpac Mill | Niagara Falls, NY | Paper Manufacturing322121 | 100–499 | ◐ LIKELY ACTIVE |
| HSHanzlian's Sausage & Deli | Cheektowaga, NY | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| HHoneywellNY15 | Buffalo, NY | Chemical Manufacturing325120 | 100–499 | ◐ LIKELY ACTIVE |
| HCHooker Chem & Plastics | North Tonawanda, NY | Chemical Manufacturing325211 | — | ◐ LIKELY ACTIVE |
| IRIngersoll Rand Compression Technologies & Services | Buffalo, NY | Machinery Manufacturing333611 | — | ◐ LIKELY ACTIVE |
| ICInnovative Concepts in Entertainment, Inc. | Clarence, NY | Miscellaneous Manufacturing339932 | 100–499 | ◐ LIKELY ACTIVE |
| IIItt INC | Orchard Park, NY | Fabricated Metal Product Manufacturing332912 | — | ◐ LIKELY ACTIVE |
| LILinde, INC. | Niagara Falls, NY | Chemical Manufacturing325120 | — | ◐ LIKELY ACTIVE |
| LLornamead | Tonawanda, NY | Chemical Manufacturing325611 | 100–499 | ◐ LIKELY ACTIVE |
| LGLpna Group INC | Tonawanda, NY | Chemical Manufacturing325611 | — | ◐ LIKELY ACTIVE |
| LSL & S Metals, Inc. | North Tonawanda, NY | Fabricated Metal Product Manufacturing332322 | 20–99 | ◐ LIKELY ACTIVE |
| MAMaterion Advanced Materials Techologies & Services INC | Niagara Falls, NY | Primary Metal Manufacturing331491 | — | ◐ LIKELY ACTIVE |
| MAMineo and Sapio's | Buffalo, NY | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| MSMission Systems Orchard Park - 10 Centre | Orchard Park, NY | Transportation Equipment Manufacturing336413 | 20–99 | ◐ LIKELY ACTIVE |
| MMModern-Tec Manufacturing, Inc. | Lockport, NY | Fabricated Metal Product Manufacturing332710 | 20–99 | ◐ LIKELY ACTIVE |
| NCNiabraze Corp-use Nyr000013334 | Tonawanda, NY | Fabricated Metal Product Manufacturing332813 | — | ◐ LIKELY ACTIVE |
| NCNiagara Craft Spirits LLC | Cambria, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| NLNiagara Label | Akron, NY | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| NSNiagara Specialty Metals, INC | Akron, NY | Primary Metal Manufacturing331111 | — | ◐ LIKELY ACTIVE |
| OCOccidental Chemical CORP. | Niagara Falls, NY | Chemical Manufacturing325180 | — | ◐ LIKELY ACTIVE |
| PPhilpac | Buffalo, NY | Paper Manufacturing322211 | 20–99 | ◐ LIKELY ACTIVE |
| PCPower City Warehouse | Niagara Falls, NY | Chemical Manufacturing325991 | — | ◐ LIKELY ACTIVE |
| PTPraxair Technology Center | Tonawanda, NY | Chemical Manufacturing325120 | — | ◐ LIKELY ACTIVE |
| PPPrecision Process INC | Niagara Falls, NY | Machinery Manufacturing333249 | 20–99 | ◐ LIKELY ACTIVE |
| PIProtective Industries INC | Buffalo, NY | Plastics and Rubber Products Manufacturing326199 | — | ◐ LIKELY ACTIVE |
| PTPrz Technologies, LLC | Lancaster, NY | Fabricated Metal Product Manufacturing332710 | 20–99 | ◐ LIKELY ACTIVE |
| RQRedland Quarries Ny Inc-lockport Quarry | Lockport, NY | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| RPRich Products Corporation | Buffalo, NY | Food Manufacturing311412 | — | ◐ LIKELY ACTIVE |
| RGRiley Gear Corporation | North Tonawanda, NY | Fabricated Metal Product Manufacturing332111 | — | ◐ LIKELY ACTIVE |
| RMRolite Mfg Inc | Lancaster, NY | Transportation Equipment Manufacturing336370 | 20–99 | ◐ LIKELY ACTIVE |
| SPSafespan Platform Systems INC | Tonawanda, NY | Primary Metal Manufacturing331111 | 100–499 | ◐ LIKELY ACTIVE |