| LPLeggett & Platt, INC. | Cape Girardeau, MO | Plastics and Rubber Products Manufacturing326299 | — | ◇ UNVERIFIED |
| MTMagna Tel Incorporated | Cape Girardeau, MO | Printing and Related Support Activities323113 | — | ◇ UNVERIFIED |
| MDMissouri Dry Dock & Repair CO | Cape Girardeau, MO | Fabricated Metal Product Manufacturing332312 | — | ◇ UNVERIFIED |
| NANorth American Tie & Timber LLC | Scott City, MO | Wood Product Manufacturing321114 | — | ◇ UNVERIFIED |
| PCPolyone-specialty Compounds | Cape Girardeau, MO | Chemical Manufacturing325991 | — | ◇ UNVERIFIED |
| QLQc, Llc, a Verdesian Life Sciences Company | Cape Girardeau, MO | Food Manufacturing311942 | — | ◇ UNVERIFIED |
| RPRam Power Environmental Services INC | Cape Girardeau, MO | Chemical Manufacturing325314 | — | ◇ UNVERIFIED |
| RIRapco Internatonal INC | Jackson, MO | Computer and Electronic Product Manufacturing334290 | — | ◇ UNVERIFIED |
| RURs Used Oil Services INC | Jackson, MO | Petroleum and Coal Products Manufacturing324191 | — | ◇ UNVERIFIED |
| RDRubbermaid - Division of Newell Rubbermaid | Jackson, MO | Plastics and Rubber Products Manufacturing326299 | — | ◇ UNVERIFIED |
| SESabre Excavating | Tamms, IL | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| SPSpartech Plastic | Cape Girardeau, MO | Plastics and Rubber Products Manufacturing326113 | — | ◇ UNVERIFIED |
| SBStandley Batch Systems INC | Cape Girardeau, MO | Fabricated Metal Product Manufacturing332420 | — | ◇ UNVERIFIED |
| TMTorque-traction Manufacturing Technologies INC | Cape Girardeau, MO | Transportation Equipment Manufacturing336211 | — | ◇ UNVERIFIED |
| ACApple Creek Vineyard & Winery LLC | Friedheim, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CICairo, IL | Cairo, IL | Food Manufacturing311224 | 20–99 | ◐ LIKELY ACTIVE |
| CCape | Cape Girardeau, MO | Beverage and Tobacco Product Manufacturing312111 | 20–99 | ◐ LIKELY ACTIVE |
| CCCustom Cut Fabrication | Jackson, MO | Fabricated Metal Product Manufacturing332710 | 20–99 | ◐ LIKELY ACTIVE |
| EAEbb and Flow | Cape Girardeau, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
 General Tool Company | Cape Girardeau, MO | Fabricated Metal Product Manufacturing332710 | 1–19 | ◐ LIKELY ACTIVE |
| GNGood News Brewing Company | Jackson, MO | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| HVHunter Valley Winery | Cape Girardeau, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| LFLudwig Farm Wine | Jackson, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| MBMinglewood Brewery | Cape Girardeau, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| MMondi | Jackson, MO | Plastics and Rubber Products Manufacturing326112 | 100–499 | ◐ LIKELY ACTIVE |
| MSMouser Steel Supply INC | Patton, MO | Transportation Equipment Manufacturing336212 | — | ◐ LIKELY ACTIVE |
| RCRothbrick Crush | Jackson, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| Sspartech | Cape Girardeau, MO | Plastics and Rubber Products Manufacturing326113 | 20–99 | ◐ LIKELY ACTIVE |
| SCSteele Crest Winery | Jackson, MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| SIStitch It International, INC. | Patton, MO | Machinery Manufacturing333248 | — | ◐ LIKELY ACTIVE |
| TGThe Greenbrier Companies, Jackson | Jackson, MO | Fabricated Metal Product Manufacturing332710 | 100–499 | ◐ LIKELY ACTIVE |
| BFBootheel Fence Company, INC. | Jackson, MO | Fabricated Metal Product Manufacturing332323 | — | ◇ UNVERIFIED |
| BLBotkin Lumber Co., INC. | Cape Girardeau, MO | Wood Product Manufacturing321920 | — | ◇ UNVERIFIED |
| CVClean Victory, LLC | Cape Girardeau, MO | Food Manufacturing311213 | — | ◇ UNVERIFIED |
| CSCo-op Service Center-jackson Facility | Jackson, MO | Food Manufacturing311119 | — | ◇ UNVERIFIED |
 David B. Knight & Associates INC. | Cape Girardeau, MO | Machinery Manufacturing333241 | — | ◇ UNVERIFIED |
| DLDavincia, LLC Dba Link Electronics | Jackson, MO | Electrical Equipment, Appliance & Component Manufacturing335999 | — | ◇ UNVERIFIED |
| DADelta Asphalt, INC. | Cape Girardeau, MO | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| EGErlbacher Gear & Machine INC. | Cape Girardeau, MO | Fabricated Metal Product Manufacturing332710 | — | ◇ UNVERIFIED |
| FCFive County Regional Vocational System | Tamms, IL | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| HMHomestead Meat Company LLC | Jackson, MO | Food Manufacturing311611 | — | ◇ UNVERIFIED |
| JMJackson Machine & Mfg, INC | Jackson, MO | Machinery Manufacturing333514 | — | ◇ UNVERIFIED |
| LMLangford Mechanical & Sheet Metal, INC. | Jackson, MO | Fabricated Metal Product Manufacturing332322 | — | ◇ UNVERIFIED |
| MAMondi Akrosil, LLC | Jackson, MO | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| PCPolyone Corporation | Cape Girardeau, MO | Plastics and Rubber Products Manufacturing326130 | — | ◇ UNVERIFIED |
| PGProctor & Gamble, CO. | Jackson, MO | Paper Manufacturing322121 | — | ◇ UNVERIFIED |
| PLPropak Logistics | Jackson, MO | Wood Product Manufacturing321920 | — | ◇ UNVERIFIED |
| QCQ C Corporation | Cape Girardeau, MO | Chemical Manufacturing325314 | — | ◇ UNVERIFIED |
| RMReady Mix Solutions LLC | Cairo, IL | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| RIReg INC | Cairo, IL | Chemical Manufacturing325998 | — | ◇ UNVERIFIED |
