| RHRoyal Home Fashions INC | Durham, NC | Apparel Manufacturing315999 | — | ◇ UNVERIFIED |
| TBTownsends Bonlee Plant #2 (9217) | Bonlee, NC | Food Manufacturing311119 | — | ◇ UNVERIFIED |
| TSTripharm Services, INC - Suite 100 (dba Alcami) | Morrisville, NC | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| UCUnicon Concrete Incorporated Plant Number 6 | Durham, NC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| UTUnited Therapeutics Corporation | Rtp, NC | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| WEWilmore Electronics CO INC | Hillsborough, NC | Electrical Equipment, Appliance & Component Manufacturing335999 | — | ◇ UNVERIFIED |
| ZGZoetis Global, INC. | Durham, NC | Food Manufacturing311119 | — | ◇ UNVERIFIED |
| 0N00030023-24 Nipcam Services of Nc Siler City | Siler City, NC | Food Manufacturing311615 | 100–499 | ◐ LIKELY ACTIVE |
| 1T1953 Twa | Morrisville, NC | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| 2W2910 Weck | Durham, NC | Printing and Related Support Activities323111 | 500+ | ◐ LIKELY ACTIVE |
| 2D293 Durham NC | Durham, NC | Food Manufacturing311811 | 20–99 | ◐ LIKELY ACTIVE |
| ANAisin North Carolina Corporation - Durham | DurhM, NC | Transportation Equipment Manufacturing336350 | 500+ | ◐ LIKELY ACTIVE |
| ADAmerican Defense Group LLC | Cary, NC | Transportation Equipment Manufacturing336992 | — | ◐ LIKELY ACTIVE |
| ANAmerican National Services LLC | Pittsboro, NC | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| AIAnduril Industries, Inc. RTP | Morrisville, NC | Transportation Equipment Manufacturing336411 | 100–499 | ◐ LIKELY ACTIVE |
| ANApex NC Panel | Apex, NC | Wood Product Manufacturing321215 | 20–99 | ◐ LIKELY ACTIVE |
| AOAp Orthopedics INC | Bahama, NC | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| APArauco Panels USA, LLC | Moncure, NC | Wood Product Manufacturing321219 | 100–499 | ◐ LIKELY ACTIVE |
| AOAtlas Organics CU02 LLC | Durham, NC | Chemical Manufacturing325314 | 1–19 | ◐ LIKELY ACTIVE |
| APAurobindo Pharma USA | Durham, NC | Chemical Manufacturing325412 | 20–99 | ◐ LIKELY ACTIVE |
| AIAvioq, Inc. | Durham, NC | Chemical Manufacturing325413 | 20–99 | ◐ LIKELY ACTIVE |
| BFBattle Fermentables LLC | Durham, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BNBeam NC | Durham, NC | Chemical Manufacturing325412 | 100–499 | ◐ LIKELY ACTIVE |
| BBioDevices | Durham, NC | Chemical Manufacturing325412 | 100–499 | ◐ LIKELY ACTIVE |
| BDBioventus - Durham | Durham, NC | Miscellaneous Manufacturing339113 | 100–499 | ◐ LIKELY ACTIVE |
| BMBrenntag Mid-south, LLC | Durham, NC | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| BCBull City Sheet Metal, LLC | Durham, NC | Fabricated Metal Product Manufacturing332322 | — | ◐ LIKELY ACTIVE |
| CGCarolina Gill Industries, LLC | Durham, NC | Textile Mills313210 | — | ▲ REPORTED CLOSED |
| CPCarolina Pure Snacks | Pittsboro, NC | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| CCenterpoint | Durham, NC | Printing and Related Support Activities323111 | 100–499 | ◐ LIKELY ACTIVE |
| CBChampions Business Services LLC | Chapel Hill, NC | Apparel Manufacturing315990 | — | ◐ LIKELY ACTIVE |
| CWChampion Window of Raleigh/Durham | Durham, NC | Plastics and Rubber Products Manufacturing326121 | 1–19 | ◐ LIKELY ACTIVE |
| CBChirpy's Barbecue, LLC | Bennett, NC | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| CGChudy Group LLC | Durham, NC | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| CMCompass Medical Technologies, INC. | Durham, NC | Computer and Electronic Product Manufacturing334510 | — | ◐ LIKELY ACTIVE |
| CDCORMETECH - Durham Manufacturing Facility | Durham, NC | Nonmetallic Mineral Product Manufacturing327992 | 100–499 | ◐ LIKELY ACTIVE |
| CICorning Incorporated Discovery Labware | Durham, NC | — | — | ◐ LIKELY ACTIVE |
| CLCorning Life Sciences | Durham, NC | Miscellaneous Manufacturing339113 | 100–499 | ◐ LIKELY ACTIVE |
| DTDefinium Therapeutics Us, INC. | Durham, NC | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| DDurham | Durham, NC | Beverage and Tobacco Product Manufacturing312120 | 1–19 | ◐ LIKELY ACTIVE |
| DDurham (Litho) | Durham, NC | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| DNDurham, NC | Durham, NC | Nonmetallic Mineral Product Manufacturing327120 | 20–99 | ◐ LIKELY ACTIVE |
| DNDurham, NC Facility | Durham, NC | Chemical Manufacturing325414 | 500+ | ◐ LIKELY ACTIVE |
| DSDurham Site | Durham, NC | Computer and Electronic Product Manufacturing334413 | 100–499 | ◐ LIKELY ACTIVE |
| DWDurham Web | Durham, NC | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| FCFireClay Cellars | Siler City, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| FDFORTNA - Durham NC | Durham, NC | Machinery Manufacturing333922 | 1–19 | ◐ LIKELY ACTIVE |
| GSGeneral Shale Moncure | Moncure, NC | Nonmetallic Mineral Product Manufacturing327120 | 20–99 | ◐ LIKELY ACTIVE |
| GHGolden Hour | Durham, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| GDGraybeard Distillery, INC. | Durham, NC | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |