| UTUnited Therapeutics Corporation- RTP | Rtp, NC | Chemical Manufacturing325412 | 500+ | ◐ LIKELY ACTIVE |
| VLVerdesian Life Sciences, LLC (RTP) | Durham, NC | Food Manufacturing311119 | 1–19 | ◐ LIKELY ACTIVE |
| WSWaldensian Style Wine | Durham, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WMWeldon Mills Distillery | Durham, NC | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| WRWolfspeed - RTP, NC | Rtp, NC | Computer and Electronic Product Manufacturing334413 | 100–499 | ◐ LIKELY ACTIVE |
| WSWolfspeed, Siler City, NC | Siler City, NC | Chemical Manufacturing325180 | 100–499 | ◐ LIKELY ACTIVE |
| EIEmitbio, INC. | Morrisville, NC | Computer and Electronic Product Manufacturing334510 | — | ◐ LIKELY ACTIVE |
| 3W311 W. CORP. | Durham, NC | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| AIAdsolution, INC | Durham, NC | Chemical Manufacturing325611 | — | ◇ UNVERIFIED |
| ACAlcami Corporation | Morrisville, NC | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| ACAlexandria Center for Life Science Durham | Durham, NC | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| AMAmpac Machinery CO. | Durham, NC | Machinery Manufacturing333120 | — | ◇ UNVERIFIED |
| ADAnalog Devices INC. | Durham, NC | Computer and Electronic Product Manufacturing334413 | — | ◇ UNVERIFIED |
| ACArdint Capital, Inc. | Durham, NC | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| ATArgos Therapeutics INC | Durham, NC | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
 Augusta Fiberglass Coatings | Semora, NC | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| AWA W North Carolina, INC. | Eno Valley, NC | Transportation Equipment Manufacturing336350 | — | ◇ UNVERIFIED |
| AIAxsom Iron Works, LLC | Siler City, NC | Fabricated Metal Product Manufacturing332323 | — | ◇ UNVERIFIED |
| BDBad Dog Enterprises LLC | Chapel Hill, NC | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| BCBear Creek Fabrication LLC | Bear Creek, NC | Fabricated Metal Product Manufacturing332312 | — | ◇ UNVERIFIED |
| BSBig Spoon Roasters, LLC | Hillsborough, NC | Food Manufacturing311911 | — | ◇ UNVERIFIED |
| BRBiogen - Rtp Drug Products Facility | Research Triangle Park, NC | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
 Blue Force Technologies, INC. | Morrisville, NC | Transportation Equipment Manufacturing336413 | — | ◇ UNVERIFIED |
| BMBonlee Mills | Siler City, NC | Food Manufacturing311119 | — | ◇ UNVERIFIED |
| BFBuilder's Firstsource, Atlantic Group, INC. | Hillsborough, NC | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| BCBull City Ciderworks | Durham, NC | Beverage and Tobacco Product Manufacturing312140 | — | ◇ UNVERIFIED |
| CCCabinet Craftsmen Specialties Dba Cks | Durham, NC | Furniture and Related Product Manufacturing337212 | — | ◇ UNVERIFIED |
| CLCarolina Lumber Enterprise, INC. | Siler City, NC | Wood Product Manufacturing321113 | — | ◇ UNVERIFIED |
| CCCarpenter CO. | Mebane, NC | Plastics and Rubber Products Manufacturing326299 | — | ◇ UNVERIFIED |
| CCCentral Carolina Concrete, LLC - Mebane | Mebane, NC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CICree, INC. | Durham, NC | Computer and Electronic Product Manufacturing334413 | — | ◇ UNVERIFIED |
| CICree, INC. | Durham, NC | Computer and Electronic Product Manufacturing334413 | — | ◇ UNVERIFIED |
| CMCustom Match Corporation | Durham, NC | Chemical Manufacturing325130 | — | ◇ UNVERIFIED |
| CSCustom Sheetmetal Services, INC. | Durham, NC | Fabricated Metal Product Manufacturing332322 | — | ◇ UNVERIFIED |
| DRDanfoss Rtp | Durham, NC | Electrical Equipment, Appliance & Component Manufacturing335311 | — | ◇ UNVERIFIED |
| DCDialight Corporation | Roxboro, NC | Computer and Electronic Product Manufacturing334413 | — | ◇ UNVERIFIED |
| DTDiaz Tires | Durham, NC | Plastics and Rubber Products Manufacturing326212 | — | ◇ UNVERIFIED |
| DDDingo Dog Brewing Company Ltd. | Carrboro, NC | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| DLDssolvr LLC | Durham, NC | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| ECEaton CORP | Durham, NC | Electrical Equipment, Appliance & Component Manufacturing335313 | — | ◇ UNVERIFIED |
| EREno River Brewing, LLC | Hillsborough, NC | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| ECEpc - Columbia, INC. | Siler City, NC | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| FLFbbc, LLC | Durham, NC | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
 Firstmark Aerospace Corporation | Durham, NC | Electrical Equipment, Appliance & Component Manufacturing335999 | — | ◇ UNVERIFIED |
| FLFizzwerks LLC | Durham, NC | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
 Flexcell International Corporation | Hillsborough, NC | Computer and Electronic Product Manufacturing334516 | — | ◇ UNVERIFIED |
| FIFsc Ii LLC Dba Fred Smith Company | Durham, NC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| FBFullsteam Brewery, LLC | Durham, NC | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| GAGe Aircraft Engines | Durham, NC | Transportation Equipment Manufacturing336412 | — | ◇ UNVERIFIED |
| GEGeneral Electric Aviation | Durham, NC | Transportation Equipment Manufacturing336412 | — | ◇ UNVERIFIED |
