| CCowpens | Cowpens, SC | Nonmetallic Mineral Product Manufacturing327331 | 20–99 | ◐ LIKELY ACTIVE |
| GGaffney | Gaffney, SC | Wood Product Manufacturing321999 | 1–19 | ◐ LIKELY ACTIVE |
| HMHamrick Mills Corporate Office | Gaffney, SC | Textile Mills313210 | 1–19 | ◐ LIKELY ACTIVE |
| HPHamrick Plant | Gaffney, SC | Textile Mills313210 | 100–499 | ◐ LIKELY ACTIVE |
| L0Lci - 074 | Gaffney, SC | Fabricated Metal Product Manufacturing332321 | 20–99 | ◐ LIKELY ACTIVE |
| LLimestone | Gaffney, SC | Textile Mills313210 | 100–499 | ◐ LIKELY ACTIVE |
| MOMill Operations Cowpens CBM | Cowpens, SC | Paper Manufacturing322121 | 100–499 | ◐ LIKELY ACTIVE |
| NPNestle Prepared Foods Company | Gaffney, SC | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| NUNestle USA, Inc. | Gaffney, SC | Food Manufacturing311412 | 500+ | ◐ LIKELY ACTIVE |
| NCNewark Corporation | Gaffney, SC | Computer and Electronic Product Manufacturing334419 | — | ◐ LIKELY ACTIVE |
| PMParkdale Mills, Inc Plant 7 | Gaffney, SC | Textile Mills313110 | 100–499 | ◐ LIKELY ACTIVE |
| RPRusken Packaging Spartanburg | Cowpens, SC | Paper Manufacturing322211 | 20–99 | ◐ LIKELY ACTIVE |
 Sticker Mule South Carolina, LLC | Gaffney, SC | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| STSuminoe Textile of America | Gaffney, SC | Textile Product Mills314110 | 100–499 | ◐ LIKELY ACTIVE |
| TMTribal Manufacturing SC | Chesnee, SC | Fabricated Metal Product Manufacturing332913 | 20–99 | ◐ LIKELY ACTIVE |
| UAUpstate Anodize LLC | Gaffney, SC | Fabricated Metal Product Manufacturing332813 | — | ◇ UNVERIFIED |
| BNBericap North America | Cowpens, SC | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| BCBoyd Corporation INC | Gaffney, SC | Plastics and Rubber Products Manufacturing326299 | — | ◇ UNVERIFIED |
| CSConcrete Supply Co., LLC - Portable 913 Logistics | Gaffney, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CCCWF Crating & Logistics | Blacksburg, SC | Wood Product Manufacturing321920 | — | ◇ UNVERIFIED |
| ESEmbroidery Solutions Mfg LLC Dbagaffney Embroidery | Gaffney, SC | Textile Product Mills314999 | — | ◇ UNVERIFIED |
| EBExperience Brands | Gaffney, SC | Electrical Equipment, Appliance & Component Manufacturing335132 | — | ◇ UNVERIFIED |
| HIHamrick Industries:plant 5 | Gaffney, SC | Textile Mills313310 | — | ◇ UNVERIFIED |
| MCMilliken & CO | Blacksburg, SC | Textile Mills313310 | — | ◇ UNVERIFIED |
| MPModerna Products America LLC | Gaffney, SC | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| NANew Age Oils, LLC | Gaffney, SC | Chemical Manufacturing325998 | — | ◇ UNVERIFIED |
| PGPiedmont Glove and Safety Mfg CORP | Gaffney, SC | Apparel Manufacturing315992 | — | ◇ UNVERIFIED |
| PSPreferred Specialities INC | Gaffney, SC | Textile Mills313311 | — | ◇ UNVERIFIED |
| RRRomeo Rim INC | Gaffney, SC | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| SCSloan Construction:blacksburg | Blacksburg, SC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| SISpectal Industries USA INC | Gaffney, SC | Wood Product Manufacturing321911 | — | ◇ UNVERIFIED |
| UAUpstate Anodize LLC | Gaffney, SC | Fabricated Metal Product Manufacturing332813 | — | ◇ UNVERIFIED |
| WMWastequip Manufacturing Company LLC | Blacksburg, SC | Fabricated Metal Product Manufacturing332439 | — | ◇ UNVERIFIED |
| WBW B Frozen US LLC | Gaffney, SC | Food Manufacturing311812 | — | ◇ UNVERIFIED |
| WFWendell Fabrics Corporation | Blacksburg, SC | Textile Mills313210 | — | ◇ UNVERIFIED |
