| ALAmericold Logistics, LLC | Sumter, SC | — | — | ◐ LIKELY ACTIVE |
 Continental Tire the Americas LLC - Sumter Plant | Sumter, SC | Plastics and Rubber Products Manufacturing326211 | 500+ | ◐ LIKELY ACTIVE |
| CWCourtney Whitney | Sumter, SC | Miscellaneous Manufacturing339999 | — | ◐ LIKELY ACTIVE |
| HCHood Container Corporation Sumter | Sumter, SC | Paper Manufacturing322211 | 100–499 | ◐ LIKELY ACTIVE |
| KBKaydon Bearings | Sumter, SC | Fabricated Metal Product Manufacturing332991 | 100–499 | ◐ LIKELY ACTIVE |
| LLLJS-Solutions, LLC | Sumter, SC | Furniture and Related Product Manufacturing337215 | 100–499 | ◐ LIKELY ACTIVE |
 Pilgrim's Pride Sumter Feed Mill | Starks Ferry Road, SC | Food Manufacturing311119 | 1–19 | ◐ LIKELY ACTIVE |
| SSSKF Sumter | Sumter, SC | Fabricated Metal Product Manufacturing332991 | 100–499 | ◐ LIKELY ACTIVE |
| SMSumter Manufacturing Plant | Sumter, SC | Electrical Equipment, Appliance & Component Manufacturing335313 | 500+ | ◐ LIKELY ACTIVE |
| SSSumter SC Truss | Sumter, SC | Wood Product Manufacturing321215 | 100–499 | ◐ LIKELY ACTIVE |
| SSylvamo | Sumter, SC | Machinery Manufacturing333243 | 100–499 | ◐ LIKELY ACTIVE |
| AIAccufab INC | Sumter, SC | Fabricated Metal Product Manufacturing332323 | — | ◇ UNVERIFIED |
| ACApac Carolina:plant 512 Sumter | Sumter, SC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| ASArmoloy Southeast Incorporated | Sumter, SC | Fabricated Metal Product Manufacturing332813 | — | ◇ UNVERIFIED |
| CBCarolina Broach Company | Sumter, SC | Machinery Manufacturing333515 | — | ◇ UNVERIFIED |
| CGConform Gissing International LLC | Sumter, SC | Chemical Manufacturing325222 | — | ◇ UNVERIFIED |
| DODawkins On-site Concrete LLC - Plant Dc#350 | Sumter, SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| ECEaton Corporation | Sumter, SC | Electrical Equipment, Appliance & Component Manufacturing335313 | — | ◇ UNVERIFIED |
 E-vac Magnetics LLC | Sumter, SC | Fabricated Metal Product Manufacturing332999 | — | ◇ UNVERIFIED |
| GLGable Log Homes | Gable, SC | Wood Product Manufacturing321113 | — | ◇ UNVERIFIED |
| GCGeddings Cabinet Shop | Sumter, SC | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| HCHarvin Choice Meats INC | Sumter, SC | Food Manufacturing311611 | — | ◇ UNVERIFIED |
| KCKaydon CORP Plant 12 | Sumter, SC | Fabricated Metal Product Manufacturing332991 | — | ◇ UNVERIFIED |
| KIKorn Industries Incorporated | Sumter, SC | Furniture and Related Product Manufacturing337122 | — | ◇ UNVERIFIED |
| MHMartins Home Improvement | Sumter, SC | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| MFMetal Finishing Services INC | Sumter, SC | Fabricated Metal Product Manufacturing332813 | — | ◇ UNVERIFIED |
| MFMount Franklin Nutritionals LLC | Sumter, SC | Food Manufacturing311330 | — | ◇ UNVERIFIED |
| OSOmni Southeastern Chem | Sumter, SC | Chemical Manufacturing325110 | — | ◇ UNVERIFIED |
| POPeach Orchard Deer Processing LLC | Dalzell, SC | Food Manufacturing311611 | — | ◇ UNVERIFIED |
| PPilgrims | Sumter, SC | Food Manufacturing311615 | — | ◇ UNVERIFIED |
| Pilgrims Pride Corporation | Sumter, SC | Food Manufacturing311615 | — | ◇ UNVERIFIED |
| PSPlatnick Steel & Engineering INC | Sumter, SC | Machinery Manufacturing333923 | — | ◇ UNVERIFIED |
| PCPower Clean Systems INC | Sumter, SC | Machinery Manufacturing333319 | — | ◇ UNVERIFIED |
| QPQuintanilla Poultry LLC | Sumter, SC | Food Manufacturing311615 | — | ◇ UNVERIFIED |
| RFRichard's Fab Shop LLC | Sumter, SC | Fabricated Metal Product Manufacturing332313 | — | ◇ UNVERIFIED |
| SCSanta Cruz Nutritionals Sumter - Phase 2 Expansion | Sumter, SC | Chemical Manufacturing325411 | — | ◇ UNVERIFIED |
| SAStateburg Auto Sales, LLC | Sumter, SC | Fabricated Metal Product Manufacturing332119 | — | ◇ UNVERIFIED |
| SLStonequarters LLC | Sumter, SC | Nonmetallic Mineral Product Manufacturing327991 | — | ◇ UNVERIFIED |
| SMSumter Material Handling INC | Sumter, SC | Transportation Equipment Manufacturing336212 | — | ◇ UNVERIFIED |
| WOWcc of Mayesville LLC | Mayesville, SC | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
