| ESEchelon Supply and Service, INC. | Liverpool, NY | Plastics and Rubber Products Manufacturing326220 | — | ◐ LIKELY ACTIVE |
| ESEchelon Supply and Service- Liverpool | Liverpool, NY | Plastics and Rubber Products Manufacturing326220 | 100–499 | ◐ LIKELY ACTIVE |
| EVEibert Vineyards | Skaneateles, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| FPFluid Power Sales Baldwinsville | Baldwinsville, NY | Machinery Manufacturing333995 | 20–99 | ◐ LIKELY ACTIVE |
| FLFoxtrot Lima Enterprises LLC | Elbridge, NY | Fabricated Metal Product Manufacturing332994 | — | ◐ LIKELY ACTIVE |
| FTFulton Thermal Corp - Benedict Rd | East Syracuse, NY | Machinery Manufacturing333414 | 20–99 | ◐ LIKELY ACTIVE |
| FTFulton Thermal Corp - Centerville Road | Pulaski, NY | Machinery Manufacturing333414 | 100–499 | ◐ LIKELY ACTIVE |
| FTFulton Thermal Corp - Running Ridge Rd | North Syracuse, NY | Machinery Manufacturing333414 | 20–99 | ◐ LIKELY ACTIVE |
| GFGiovanni Food Co Inc | Baldwinsville, NY | Food Manufacturing311421 | 100–499 | ◐ LIKELY ACTIVE |
| GTGrace Tyler Estate Winery, LLC | Constantia, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| GWGreenwood Winery, LLC | East Syracuse, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| HIHall Island Distillery | Cicero, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| HPHanford Pharmaceuticals | Syracuse, NY | Chemical Manufacturing325412 | 100–499 | ◐ LIKELY ACTIVE |
| HMHarvest Moon Cidery | Cazenovia, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| HHHunter & Hilsberg Corporation | Syracuse, NY | Food Manufacturing311421 | — | ◐ LIKELY ACTIVE |
| ILIconex, LLC Liverpool | Liverpool, NY | Paper Manufacturing322230 | 20–99 | ◐ LIKELY ACTIVE |
Immediate Mailing Services, Inc. | Liverpool, NY | Printing and Related Support Activities323111 | 100–499 | ◐ LIKELY ACTIVE |
| IIInfitec, Inc. | East Syracuse, NY | Electrical Equipment, Appliance & Component Manufacturing335314 | 20–99 | ◐ LIKELY ACTIVE |
| JTJMA Tech Properties LLC | Syracuse, NY | Computer and Electronic Product Manufacturing334220 | 20–99 | ◐ LIKELY ACTIVE |
John Mezzalingua Associates LLC dba JMA Wireless Warehouse Liverpool | Liverpool, NY | Computer and Electronic Product Manufacturing334220 | 1–19 | ◐ LIKELY ACTIVE |
| JFJordan Facility | Jordan, NY | Primary Metal Manufacturing331420 | 20–99 | ◐ LIKELY ACTIVE |
| LWLakeland Winery, INC. | Syracuse, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| LSLast Shot Distillery | Skaneateles, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| LOLife of Reilley Distilling Co. | Cazenovia, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| LGLoa-mar Group LLC | Syracuse, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| L1Lock 1 Distilling Company | Phoenix, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| LMLockheed Martin Corporation US NY Syracuse Electroncs Pkwy (1021) | Liverpool, NY | Computer and Electronic Product Manufacturing334511 | 500+ | ◐ LIKELY ACTIVE |
| LBLOTTE Biologics USA, LLC | East Syracuse, NY | Chemical Manufacturing325414 | 100–499 | ◐ LIKELY ACTIVE |
| MCMadison County Distillery, LLC | Cazenovia, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| MManth-Brownell | Kirkville, NY | Fabricated Metal Product Manufacturing332721 | 20–99 | ◐ LIKELY ACTIVE |
| MPMidstate Printing Corp | Liverpool, NY | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| MOMill Operations Solvay CBM | Syracuse, NY | Paper Manufacturing322121 | 100–499 | ◐ LIKELY ACTIVE |
| MIMillwood, Inc. Syracuse | East Syracuse, NY | Wood Product Manufacturing321920 | 1–19 | ◐ LIKELY ACTIVE |
| MMMorse Manufacturing Co Inc | Syracuse, NY | Machinery Manufacturing333924 | 20–99 | ◐ LIKELY ACTIVE |
| MMMoses Mountain Spirits | Marcellus, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| NONavarino Orchard LLC | Syracuse, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| NJNYC Jamesville | Jamesville, NY | Petroleum and Coal Products Manufacturing324121 | 20–99 | ◐ LIKELY ACTIVE |
| NSNY Syracuse AD | Cicero, NY | Transportation Equipment Manufacturing336212 | 20–99 | ◐ LIKELY ACTIVE |
| OHOld Home Distillers | Lebanon, NY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| OOptogenics | Syracuse, NY | Miscellaneous Manufacturing339115 | 20–99 | ◐ LIKELY ACTIVE |
| OAOrthopedic Appliances of Central New York, INC | Syracuse, NY | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| PAPackaged Air-conditioning Service CORP | Liverpool, NY | Computer and Electronic Product Manufacturing334512 | — | ◐ LIKELY ACTIVE |
| PTPak Technologies - Syracuse | Syracuse, NY | Chemical Manufacturing325520 | 1–19 | ◐ LIKELY ACTIVE |
| PDPaul Delima Co., Inc. | Cicero, NY | Food Manufacturing311920 | 20–99 | ◐ LIKELY ACTIVE |
| PSPharmalogic Syracuse, LLC | Syracuse, NY | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| PSPPC Syracuse | Syracuse, NY | Computer and Electronic Product Manufacturing334417 | 100–499 | ◐ LIKELY ACTIVE |
| PHPremier Hardwood Products, Inc. | Syracuse, NY | Wood Product Manufacturing321918 | 20–99 | ◐ LIKELY ACTIVE |
Prime Materials Recovery, Inc, Ny | Canastota, NY | Fabricated Metal Product Manufacturing332999 | 20–99 | ◐ LIKELY ACTIVE |
| RRam | Syracuse, NY | Fabricated Metal Product Manufacturing332996 | 20–99 | ◐ LIKELY ACTIVE |
| RHRed Hawk Brewing, LTD | Syracuse, NY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |