| PPalletone | Mocksville, NC | Wood Product Manufacturing321920 | 20–99 | ◐ LIKELY ACTIVE |
| POPalletOne o Mocksville | Mocksville, NC | Wood Product Manufacturing321920 | 20–99 | ◐ LIKELY ACTIVE |
| PMParkdale Mills, Inc Plant 6 & 45 | Thomasville, NC | Textile Mills313110 | 20–99 | ◐ LIKELY ACTIVE |
| POPBV-Western Operations Warehouse | Winston Salem, NC | Beverage and Tobacco Product Manufacturing312112 | 500+ | ◐ LIKELY ACTIVE |
| POPBV-Winston Ops | Winston Salem, NC | Beverage and Tobacco Product Manufacturing312111 | 100–499 | ◐ LIKELY ACTIVE |
| PAPiedmont Aviation Component Services Kern | Kernersville, NC | Transportation Equipment Manufacturing336412 | 20–99 | ◐ LIKELY ACTIVE |
| PCPiedmont Candy Company | Lexington, NC | Food Manufacturing311340 | 20–99 | ◐ LIKELY ACTIVE |
| P0Plant 05 | Lexington, NC | Furniture and Related Product Manufacturing337122 | 20–99 | ◐ LIKELY ACTIVE |
| P0Plant 06 | Lexington, NC | Furniture and Related Product Manufacturing337122 | 20–99 | ◐ LIKELY ACTIVE |
| P1Plant 1 | Advance, NC | Beverage and Tobacco Product Manufacturing312112 | 20–99 | ◐ LIKELY ACTIVE |
| P1Plant 1 | Denton, NC | Fabricated Metal Product Manufacturing332119 | 100–499 | ◐ LIKELY ACTIVE |
| P2Plant 2 | Mocksville, NC | Beverage and Tobacco Product Manufacturing312112 | 1–19 | ◐ LIKELY ACTIVE |
| P3Plant 3 | Mocksville, NC | Beverage and Tobacco Product Manufacturing312112 | 1–19 | ◐ LIKELY ACTIVE |
| P3Plant 3/Bolt | Denton, NC | Fabricated Metal Product Manufacturing332119 | 20–99 | ◐ LIKELY ACTIVE |
| PCPrecast Concrete Concepts, LLC | Lewisville, NC | Nonmetallic Mineral Product Manufacturing327331 | — | ◐ LIKELY ACTIVE |
| QIQst Industries, INC | Mocksville, NC | Apparel Manufacturing315990 | — | ◐ LIKELY ACTIVE |
| RWRayson Winery & Vineyards | Mocksville, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| RMRJRT Main Office | Winston Salem, NC | Beverage and Tobacco Product Manufacturing312230 | 100–499 | ◐ LIKELY ACTIVE |
| RRRobert Rust Foods | Winston-Salem, NC | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| RFRotork Fairchild | Winston Salem, NC | Machinery Manufacturing333995 | 20–99 | ◐ LIKELY ACTIVE |
| RSRTD Seals dba Hercules OEM NC | Winston Salem, NC | Plastics and Rubber Products Manufacturing326291 | 20–99 | ◐ LIKELY ACTIVE |
| SOSalem One - Winston-Salem Plant | Winston Salem, NC | Printing and Related Support Activities323111 | 100–499 | ◐ LIKELY ACTIVE |
| SSSalem Sports Events, LLC | Winston Salem, NC | Miscellaneous Manufacturing339950 | 100–499 | ◐ LIKELY ACTIVE |
| SRSanders Ridge Vineyard & Winery | Boonville, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| SSShadow Springs Vineyard | Hamptonville, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| SCSharpe Co WS | Winston Salem, NC | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| SMShuler Meats, Inc. | Thomasville, NC | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| SESiemens Energy, INC. | Rural Hall, NC | Machinery Manufacturing333611 | — | ◐ LIKELY ACTIVE |
| SESiemens Energy Inc. Winston Service Center | Rural Hall, NC | Machinery Manufacturing333611 | 100–499 | ◐ LIKELY ACTIVE |
| SISoutheastern Installation, Inc. | Lexington, NC | Machinery Manufacturing333249 | 20–99 | ◐ LIKELY ACTIVE |
 Sportsfield Specialties, Inc. - North Carolina | Mocksville, NC | Miscellaneous Manufacturing339920 | 20–99 | ◐ LIKELY ACTIVE |
| SWStewarts Wood Products | Danbury, NC | Wood Product Manufacturing321113 | 20–99 | ◐ LIKELY ACTIVE |
| SIStoropack, Inc. - Winston Salem | Winston Salem, NC | Plastics and Rubber Products Manufacturing326140 | 1–19 | ◐ LIKELY ACTIVE |
| SHSweet Home Carolina Vineyard and Winery, LLC | Yadkinville, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TRT1 Reprocessing Center | Yadkinville, NC | Textile Mills313110 | 1–19 | ◐ LIKELY ACTIVE |
| TCTexTech Coatings | Kernersville, NC | Textile Mills313310 | 100–499 | ◐ LIKELY ACTIVE |
| TTwisting | Yadkinville, NC | Textile Mills313310 | 1–19 | ◐ LIKELY ACTIVE |
| UTUSA Thomasville NC | Thomasville, NC | Wood Product Manufacturing321213 | 500+ | ◐ LIKELY ACTIVE |
| UDUS Duct, Kernerville | Kernersville, NC | Fabricated Metal Product Manufacturing332313 | 20–99 | ◐ LIKELY ACTIVE |
| UFUS Foods, Inc. | Lexington, NC | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| VMVincenzo Manufacturing Industries (Mazzella Piedmont) | Winston Salem, NC | Machinery Manufacturing333923 | 20–99 | ◐ LIKELY ACTIVE |
| WWWeathervane Winery and Events LLC | Lexington, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WCWGS CID Plant | Denton, NC | Transportation Equipment Manufacturing336211 | 1–19 | ◐ LIKELY ACTIVE |
| Wwieland | Pine Hall, NC | Primary Metal Manufacturing331420 | 100–499 | ◐ LIKELY ACTIVE |
| WPWilliams Printing LLC | Rural Hall, NC | Printing and Related Support Activities323111 | 20–99 | ◐ LIKELY ACTIVE |
| WRWindsor Run Cellars, INC. | Hamptonville, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WWinston | Winston Salem, NC | Machinery Manufacturing333120 | 1–19 | ◐ LIKELY ACTIVE |
| WSWinston Salem NC | Winston Salem, NC | Transportation Equipment Manufacturing336510 | 100–499 | ◐ LIKELY ACTIVE |
| WSWinston Steel, LLC - Junia Location | Winston Salem, NC | Fabricated Metal Product Manufacturing332312 | 1–19 | ◐ LIKELY ACTIVE |
| WMWise Man Brewing LLC | Winston Salem, NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
