| COChemstation of South Carolina | Columbia | SC | Chemical Manufacturing325611 | 20-99 | ◐ LIKELY ACTIVE |
| CWCulpeper Wood Preservers of Columbia INC. | Columbia | SC | Wood Product Manufacturing321114 | 20-99 | ◐ LIKELY ACTIVE |
| MSMiwon Specialty Chemical USA INC | Columbia | SC | Chemical Manufacturing325199 | 20-99 | ◐ LIKELY ACTIVE |
| LCLindau Chemicals, INC. | Columbia | SC | Chemical Manufacturing325194 | 20-99 | ◐ LIKELY ACTIVE |
| RIRhythmlink International LLC | Columbia | SC | Computer and Electronic Product Manufacturing334510 | 20-99 | ▲ REPORTED CLOSED |
| TEThermal Engineering Corporation | Columbia | SC | Machinery Manufacturing333994 | 20-99 | ◐ LIKELY ACTIVE |
| 0K00060239-23965 Kci Tech - Columbia, Sc | Columbia | SC | Fabricated Metal Product Manufacturing332410 | 20-99 | ◐ LIKELY ACTIVE |
| 0G051 Garners Ferry/Columbia SC | Columbia | SC | Food Manufacturing311811 | 20-99 | ◐ LIKELY ACTIVE |
| CWChampion Window of Columbia | Columbia | SC | Plastics and Rubber Products Manufacturing326121 | 20-99 | ◐ LIKELY ACTIVE |
| CRCMC Rebar Columbia | Columbia | SC | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| CSColumbia SC Millwork | Columbia | SC | Furniture and Related Product Manufacturing337212 | 20-99 | ◐ LIKELY ACTIVE |
| GGGSC - Groundworks Supply Chain | Columbia | SC | Primary Metal Manufacturing331210 | 20-99 | ◐ LIKELY ACTIVE |
| NMNew Millennium Building Systems, LLC. - Columbia | Columbia | SC | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| QPQ Plant | Columbia | SC | Machinery Manufacturing333241 | 20-99 | ◐ LIKELY ACTIVE |
| RAREI Automation, Inc. | Columbia | SC | Machinery Manufacturing333519 | 20-99 | ◐ LIKELY ACTIVE |
| SCSamtec Columbia Design Center | Columbia | SC | Computer and Electronic Product Manufacturing334417 | 20-99 | ◐ LIKELY ACTIVE |
| WCWGS Columbia | Columbia | SC | Transportation Equipment Manufacturing336510 | 20-99 | ◐ LIKELY ACTIVE |