 Patterson Fan Company | Blythewood | SC | Machinery Manufacturing333413 | — | ● ACTIVE |
| CSConcrete Supply CO LLC Blythewood | Blythewood | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| ARAmcor Rigid Packaging | Blythewood | SC | Plastics and Rubber Products Manufacturing326160 | 100-499 | ◐ LIKELY ACTIVE |
| CNCharter Next Generation | Blythewood | SC | Plastics and Rubber Products Manufacturing326112 | 100-499 | ◐ LIKELY ACTIVE |
| CBConstantia Blythewood LLC | Blythewood | SC | Printing and Related Support Activities323120 | 100-499 | ◐ LIKELY ACTIVE |
| JNJTEKT North America | Blythewood | SC | Fabricated Metal Product Manufacturing332991 | 500+ | ◐ LIKELY ACTIVE |
| OCOwens Corning Non-woven LLC - Blythewood | Blythewood | SC | Textile Mills313230 | — | ◐ LIKELY ACTIVE |
| SSSpirax Sarco Incorporated | Blythewood | SC | Fabricated Metal Product Manufacturing332911 | — | ◐ LIKELY ACTIVE |
| SCSws Con-e-co Plant | Blythewood | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| IPIntertape Polymer CORP | Blythewood | SC | Paper Manufacturing322220 | — | ◇ UNVERIFIED |
| KRKnights Redi-mix Midlands LLC Plant 6 Blythewood | Blythewood | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| LGLinde Gas | Blythewood | SC | Chemical Manufacturing325120 | — | ◇ UNVERIFIED |
| PFPatterson Fan - Office Addition | Blythewood | SC | Machinery Manufacturing333411 | — | ◇ UNVERIFIED |
| SDSiemens Diesel Systems Technology | Blythewood | SC | Transportation Equipment Manufacturing336211 | — | ◇ UNVERIFIED |
| BBlythewood | Blythewood | SC | Paper Manufacturing322220 | 100-499 | ◐ LIKELY ACTIVE |
| CFCandy Friday Farms, LLC | Blythewood | SC | Chemical Manufacturing325320 | — | ◐ LIKELY ACTIVE |
| MIManchester Industries Columbia | Blythewood | SC | Paper Manufacturing322299 | 1-19 | ◐ LIKELY ACTIVE |
| XCXerxes Corporation | Blythewood | SC | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| AMAccutech Machine INC. | Blythewood | SC | Fabricated Metal Product Manufacturing332710 | — | ◇ UNVERIFIED |
| BEBuck Enterprise LLC | Blythewood | SC | Primary Metal Manufacturing331491 | — | ◇ UNVERIFIED |
| KMKrm Midlands-llc-plant 6 | Blythewood | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
 Linde Gas & Equipment Inc/blythewood Plant | Blythewood | SC | Chemical Manufacturing325120 | — | ◇ UNVERIFIED |
| ZLZwc LLC | Blythewood | SC | Wood Product Manufacturing321999 | — | ◇ UNVERIFIED |
