| TCTwin City Fan Cos Brookings | Brookings | SD | Machinery Manufacturing333412 | — | ◐ LIKELY ACTIVE |
| DIDaktronics Incorporated | Brookings | SD | Miscellaneous Manufacturing339950 | — | ◐ LIKELY ACTIVE |
| BBBel Brands USA | Brookings | SD | Food Manufacturing311513 | 100-499 | ◐ LIKELY ACTIVE |
| TCTwin City Fan Companies LTD. | Brookings | SD | Machinery Manufacturing333413 | — | ◐ LIKELY ACTIVE |
| BPBrookings Prince Dr Facility | Brookings | SD | Plastics and Rubber Products Manufacturing326199 | 100-499 | ◐ LIKELY ACTIVE |
| BPBrookings-sd-falcon Plastics | Brookings | SD | Miscellaneous Manufacturing339113 | 1-19 | ◐ LIKELY ACTIVE |
| BWBrookings - Warehouse 1 | Brookings | SD | Miscellaneous Manufacturing339999 | 1-19 | ◐ LIKELY ACTIVE |
| BWBrookings - Warehouse 2 | Brookings | SD | Miscellaneous Manufacturing339999 | 1-19 | ◐ LIKELY ACTIVE |
| BWBrookings - Warehouse 3 | Brookings | SD | Miscellaneous Manufacturing339999 | 1-19 | ◐ LIKELY ACTIVE |
| CTClr Timber Holdings, INC. | Brookings | OR | Wood Product Manufacturing321113 | — | ◐ LIKELY ACTIVE |
| CFCounterpart Fabrication | Brookings | SD | Fabricated Metal Product Manufacturing332322 | 20-99 | ◐ LIKELY ACTIVE |
| LMLarson Mfg. LLC | Brookings | SD | Fabricated Metal Product Manufacturing332321 | 100-499 | ◐ LIKELY ACTIVE |
| MMedgene | Brookings | SD | Chemical Manufacturing325414 | 100-499 | ◐ LIKELY ACTIVE |
| NNNovita Nutrition, LLC | Brookings | SD | Food Manufacturing311119 | 20-99 | ◐ LIKELY ACTIVE |
| PAPrairie AquaTech dba Houdek | Brookings | SD | Food Manufacturing311119 | 1-19 | ◐ LIKELY ACTIVE |
| RPRainbow Play Systems, Inc. | Brookings | SD | Miscellaneous Manufacturing339920 | 20-99 | ◐ LIKELY ACTIVE |
| RPRoyal Plastics Inc. | Brookings | SD | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| SDSuperfly Distilling Company | Brookings | OR | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |