| BMBear Metallurgical Mfg | Butler | PA | Primary Metal Manufacturing331110 | 1-19 | ◐ LIKELY ACTIVE |
| BCButler Color Press/butler | Butler | PA | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| BTButler Technologies Inc | Butler | PA | Printing and Related Support Activities323113 | 20-99 | ◐ LIKELY ACTIVE |
| UPUnited Plate Glass Company (Butler) | Butler | PA | Nonmetallic Mineral Product Manufacturing327215 | 100-499 | ◐ LIKELY ACTIVE |
| FIFilmtronics INC | Butler | PA | Chemical Manufacturing325998 | 20-99 | ◐ LIKELY ACTIVE |
| AIAgr International, Inc. | Butler | PA | Computer and Electronic Product Manufacturing334519 | 100-499 | ◐ LIKELY ACTIVE |
| CCCleveland Cliffs Steel Corp/ Butler Works | Butler | PA | Primary Metal Manufacturing331110 | — | ◐ LIKELY ACTIVE |
| EIErsvin Inds. INC. Amasteel Div. | Butler, | PA | Nonmetallic Mineral Product Manufacturing327910 | — | ◐ LIKELY ACTIVE |
| HMHarsco Metals - Butler | Butler | PA | Nonmetallic Mineral Product Manufacturing327992 | — | ◐ LIKELY ACTIVE |
| JIJsp Intl Mfg | Butler | PA | Plastics and Rubber Products Manufacturing326140 | — | ◐ LIKELY ACTIVE |
| OSOesterlings Sandblasting/butler | Butler | PA | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| ASAk Steel Corp/butler Works | Butler | PA | Primary Metal Manufacturing331110 | — | ◐ LIKELY ACTIVE |
| EAErvin Amasteel-Butler Plant | Butler | PA | Nonmetallic Mineral Product Manufacturing327910 | 20-99 | ◐ LIKELY ACTIVE |
| HDHansotte Dental Laboratory | Butler | PA | Miscellaneous Manufacturing339116 | 1-19 | ◐ LIKELY ACTIVE |
| WAWiest Asphalt Prod - Butler Facility | Butler | PA | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| BPBiofab Products, INC. | Butler | PA | Fabricated Metal Product Manufacturing332312 | 1-19 | ◐ LIKELY ACTIVE |
| TBTransflo Butler Terminal | Butler | PA | Food Manufacturing311613 | — | ◐ LIKELY ACTIVE |
| AGAmerican Glass Research | Butler | PA | Computer and Electronic Product Manufacturing334519 | 1-19 | ◐ LIKELY ACTIVE |
| JDJohnny's Distillery, LLC | Butler | PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| JBJSP - Butler | Butler | PA | Plastics and Rubber Products Manufacturing326199 | 100-499 | ◐ LIKELY ACTIVE |
| KIKenjer Industries | Butler | PA | Transportation Equipment Manufacturing336413 | — | ◐ LIKELY ACTIVE |
| LVLiminal Vines LLC | Butler | PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| MQMiller's Quality Meats, LLC | Butler | PA | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| RARustic Acres Winery LLC | Butler | PA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WIWulco, INC. | Butler | PA | Transportation Equipment Manufacturing336211 | — | ◐ LIKELY ACTIVE |