| OCOMF Charlotte | Charlotte | NC | Furniture and Related Product Manufacturing337910 | 20-99 | ◐ LIKELY ACTIVE |
| OLOsprea Logistics Charlotte | Charlotte | NC | Transportation Equipment Manufacturing336992 | 1-19 | ◐ LIKELY ACTIVE |
| PCP12 Charlotte | Charlotte | NC | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| PPPapa Pies LLC | Charlotte | NC | Food Manufacturing311813 | — | ◐ LIKELY ACTIVE |
| PMPerforated Metals Plus 353 | Charlotte | NC | Fabricated Metal Product Manufacturing332119 | 1-19 | ◐ LIKELY ACTIVE |
| PHPiazza Homes, LLC | Charlotte | NC | Machinery Manufacturing333924 | — | ◐ LIKELY ACTIVE |
| PGPrimero Games, LLC - NC | Charlotte | NC | Miscellaneous Manufacturing339999 | 1-19 | ◐ LIKELY ACTIVE |
| PIPrintful, INC Westlake | Charlotte | NC | Printing and Related Support Activities323111 | 500+ | ◐ LIKELY ACTIVE |
| QCQualitrol Corp | Charlotte | NC | Electrical Equipment, Appliance & Component Manufacturing335311 | 1-19 | ◐ LIKELY ACTIVE |
| QOQuantum Optics Jena Corporation | Charlotte | NC | Computer and Electronic Product Manufacturing334210 | — | ◐ LIKELY ACTIVE |
| QSQuarry Spirits, LLC | Charlotte | MI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| RCRed Clay Ciderworks | Charlotte | NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| RARekha Ayeva | Charlotte | NC | Furniture and Related Product Manufacturing337214 | — | ◐ LIKELY ACTIVE |
| RRevMax | Charlotte | NC | Transportation Equipment Manufacturing336350 | 20-99 | ◐ LIKELY ACTIVE |
| RRRGX Rim Repair - Charlotte | Charlotte | NC | Transportation Equipment Manufacturing336390 | 1-19 | ◐ LIKELY ACTIVE |
| RTRite Time | Charlotte | NC | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| RCRsm Company | Charlotte | NC | Chemical Manufacturing325220 | — | ◐ LIKELY ACTIVE |
| RBR.t. Barbee Company, INC. | Charlotte | NC | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| RCRuggable Charlotte | Charlotte | NC | Textile Product Mills314110 | 100-499 | ◐ LIKELY ACTIVE |
| SCS C Johnson Professional Usa, INC | Charlotte | NC | Chemical Manufacturing325611 | — | ◐ LIKELY ACTIVE |
| SSScott Systems International, Inc. | Charlotte | NC | Computer and Electronic Product Manufacturing334512 | 20-99 | ◐ LIKELY ACTIVE |
| SESeaside Enterprises and Holdings, LLC | Charlotte | NC | Food Manufacturing311421 | — | ◐ LIKELY ACTIVE |
| SLSedicio LLC | Charlotte | NC | Transportation Equipment Manufacturing336991 | — | ◐ LIKELY ACTIVE |
| SCSEK Corporation / NC Remote | Charlotte | NC | Nonmetallic Mineral Product Manufacturing327390 | 1-19 | ◐ LIKELY ACTIVE |
| SCSEL Charlotte NC | Charlotte | NC | Electrical Equipment, Appliance & Component Manufacturing335314 | 100-499 | ◐ LIKELY ACTIVE |
| SJSeven Jars Distillery, LLC | Charlotte | NC | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| SJSeven Jars Products, LLC | Charlotte | NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| SCSharpe Co CH | Charlotte | NC | Printing and Related Support Activities323111 | 1-19 | ◐ LIKELY ACTIVE |
| SCShop Charlotte | Charlotte | NC | Nonmetallic Mineral Product Manufacturing327320 | 1-19 | ◐ LIKELY ACTIVE |
| SPSiena Plastics / Mauser Packaging Solutions | Charlotte | NC | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| SPSolventum Purifcation, Inc. | Charlotte | NC | Miscellaneous Manufacturing339113 | 100-499 | ◐ LIKELY ACTIVE |
| SYStock Yards Charlotte | Charlotte | NC | Food Manufacturing311612 | 20-99 | ◐ LIKELY ACTIVE |
| SEStryten Energy, LLC - Charlotte | Charlotte | NC | Electrical Equipment, Appliance & Component Manufacturing335911 | 1-19 | ◐ LIKELY ACTIVE |
| SPSurface Products Pros | Charlotte | NC | Furniture and Related Product Manufacturing337110 | 1-19 | ◐ LIKELY ACTIVE |
| SCSur-Seal Charlotte | Charlotte | NC | Miscellaneous Manufacturing339991 | 100-499 | ◐ LIKELY ACTIVE |
| THTar Heel NC MF Millwork | Charlotte | NC | Wood Product Manufacturing321918 | 20-99 | ◐ LIKELY ACTIVE |
| TBTDP Bakery Charlotte | Charlotte | NC | Food Manufacturing311812 | 20-99 | ◐ LIKELY ACTIVE |
| TFTeledyne FLIR Optical Components Group | Charlotte | NC | Machinery Manufacturing333314 | 20-99 | ◐ LIKELY ACTIVE |
| TLTerraloam LLC | Charlotte | NC | Apparel Manufacturing315250 | — | ◐ LIKELY ACTIVE |
| TIThe Imagine Group | Charlotte | NC | Printing and Related Support Activities323111 | 100-499 | ◐ LIKELY ACTIVE |
| TWThe Wine Down Enterprise LLC | Charlotte | NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TCTrystar Charlotte | Charlotte | NC | Electrical Equipment, Appliance & Component Manufacturing335313 | 20-99 | ◐ LIKELY ACTIVE |
| TFTwoCan Fermentive | Charlotte | NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| UNUSA NC Charlotte Plant | Charlotte | NC | Chemical Manufacturing325510 | 20-99 | ◐ LIKELY ACTIVE |
| VGVald Group INC | Charlotte | NC | Miscellaneous Manufacturing339920 | — | ◐ LIKELY ACTIVE |
| VIVestcom International, Charlotte NC | Charlotte | NC | Printing and Related Support Activities323111 | 100-499 | ◐ LIKELY ACTIVE |
| VWVinorita Wine Slushies | Charlotte | NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| VCVitek Corporation | Charlotte | NC | Machinery Manufacturing333248 | — | ◐ LIKELY ACTIVE |
| WVWard Vessel And Exchanger | Charlotte | NC | Fabricated Metal Product Manufacturing332420 | 20-99 | ◐ LIKELY ACTIVE |
| WTWatchdog Tactical LLC | Charlotte | NC | Miscellaneous Manufacturing339920 | — | ◐ LIKELY ACTIVE |