| PSPixelle Specialty Solutions LLC (0671010028) | Chillicothe | OH | Paper Manufacturing322120 | — | ◐ LIKELY ACTIVE |
| WRWire Rope Corporation of America-chillicothe Plant | Chillicothe | MO | Primary Metal Manufacturing331222 | — | ◐ LIKELY ACTIVE |
| CCChillicothe Correctional Institution | Chillicothe | OH | Fabricated Metal Product Manufacturing332710 | — | ◐ LIKELY ACTIVE |
| CIChillicothe Iron & Steel, INC. | Chillicothe | MO | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| MQMidwest Quality Gloves INC - Chillicothe | Chillicothe | MO | Apparel Manufacturing315211 | — | ◐ LIKELY ACTIVE |
| CICaterpillar INC Facility H | Chillicothe | IL | Plastics and Rubber Products Manufacturing326291 | — | ◐ LIKELY ACTIVE |
| ALAmericold Logistics, LLC | Chillicothe | MO | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| BBso | Chillicothe | OH | Fabricated Metal Product Manufacturing332613 | 20-99 | ◐ LIKELY ACTIVE |
| CFCal-Maine Foods Inc. | Chillicothe | TX | Food Manufacturing311119 | 1-19 | ◐ LIKELY ACTIVE |
| CPChillicothe Plant | Chillicothe | OH | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| DMDeLaval Manufacturing Chillicothe | Chillicothe | MO | Plastics and Rubber Products Manufacturing326291 | 20-99 | ◐ LIKELY ACTIVE |
| HFHerr Foods - 021 Production Chillicothe | Chillicothe | OH | Food Manufacturing311919 | 20-99 | ◐ LIKELY ACTIVE |
| HFHerr Foods - 065 Chillicothe OH | Chillicothe | OH | Food Manufacturing311919 | 20-99 | ◐ LIKELY ACTIVE |
| JGJohn Graves Food Service | Chillicothe | MO | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| JCJ.t.fennell Co., INC. | Chillicothe | IL | Fabricated Metal Product Manufacturing332312 | 500+ | ◐ LIKELY ACTIVE |
| JMJust Meats, LLC | Chillicothe | OH | Food Manufacturing311611 | — | ◐ LIKELY ACTIVE |
| MPMauser Packaging Solutions | Chillicothe | MO | Plastics and Rubber Products Manufacturing326160 | 20-99 | ◐ LIKELY ACTIVE |
| MMitchell | Chillicothe | MO | Machinery Manufacturing333514 | 20-99 | ◐ LIKELY ACTIVE |
| NGNIC Global-OH | Chillicothe | OH | Fabricated Metal Product Manufacturing332322 | 20-99 | ◐ LIKELY ACTIVE |
| PCPepsi Cola Bottling of Brookfield, Inc. | Chillicothe | MO | Beverage and Tobacco Product Manufacturing312111 | 20-99 | ◐ LIKELY ACTIVE |
| PSPixelle Speciality Solutions LLC | Chillicothe | OH | Paper Manufacturing322121 | 500+ | ◐ LIKELY ACTIVE |
| VIVitatoe Industries | Chillicothe | OH | Transportation Equipment Manufacturing336120 | 100-499 | ◐ LIKELY ACTIVE |