| KKks | Columbia | SC | Food Manufacturing311111 | 100-499 | ◐ LIKELY ACTIVE |
| KHKraft Heinz Foods Company | Columbia | MO | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| LHLandmark Hospitals | Columbia | MO | Transportation Equipment Manufacturing336212 | 100-499 | ◐ LIKELY ACTIVE |
| LGLaser Graphictronics LLC | Columbia | MO | Computer and Electronic Product Manufacturing334418 | — | ◐ LIKELY ACTIVE |
| LALost Ark Distilling Company | Columbia | MD | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| MMMetro Marble and Granite of Columbia DBA Central Missouri Countertops | Columbia | MO | Nonmetallic Mineral Product Manufacturing327991 | 20-99 | ◐ LIKELY ACTIVE |
| MRMid-Atlantic Regional (MAT) | Columbia | MD | Computer and Electronic Product Manufacturing334516 | 20-99 | ◐ LIKELY ACTIVE |
| NMNew Millennium Building Systems, LLC. - Columbia | Columbia | SC | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| OMOld Monroe Distilling Co. | Columbia | IL | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| ODOntrak Designs INC | Columbia | TN | Transportation Equipment Manufacturing336413 | — | ◐ LIKELY ACTIVE |
| ODOversea Distillery | Columbia | MD | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| OPOzark Plateau Pork, LLC | Columbia | MO | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| PBPalmetto Brace Shop INC | Columbia | SC | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| P8Plant 8S | Columbia | SC | Chemical Manufacturing325220 | 100-499 | ◐ LIKELY ACTIVE |
| PDPour Dog | Columbia | PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| FC"Production Facilities - Columbia, MD" | Columbia | MD | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| PAPROOF Alcohol Ice Cream | Columbia | SC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| QPQ Plant | Columbia | SC | Machinery Manufacturing333241 | 20-99 | ◐ LIKELY ACTIVE |
| RWRassawek Winery | Columbia | VA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| RAREI Automation, Inc. | Columbia | SC | Machinery Manufacturing333519 | 20-99 | ◐ LIKELY ACTIVE |
| RORobertson Optical Laboratories | Columbia | SC | Miscellaneous Manufacturing339115 | — | ◐ LIKELY ACTIVE |
| RWRose Welding & Crane Service INC | Columbia | NC | Machinery Manufacturing333923 | — | ◐ LIKELY ACTIVE |
| SCSamtec Columbia Design Center | Columbia | SC | Computer and Electronic Product Manufacturing334417 | 20-99 | ◐ LIKELY ACTIVE |
| SHSea Hunt Boats Manufacturing Co Inc | Columbia | SC | Transportation Equipment Manufacturing336611 | 100-499 | ◐ LIKELY ACTIVE |
| SPShakespeare's Pizza, Inc. | Columbia | MO | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| SLSix20distributor LLC | Columbia | SC | Computer and Electronic Product Manufacturing334220 | — | ◐ LIKELY ACTIVE |
| SNSmith + Nephew Columbia MD | Columbia | MD | Chemical Manufacturing325414 | 100-499 | ◐ LIKELY ACTIVE |
| SESnyder Engineering, Inc. | Columbia | MO | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| SRSouthern Ridge Farm LLC | Columbia | TN | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| SHSteel Hands Distilling | Columbia | SC | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| SPSteel Pro INC | Columbia | MD | Fabricated Metal Product Manufacturing332312 | — | ◐ LIKELY ACTIVE |
| STSun Technical Services, INC. | Columbia | MD | Beverage and Tobacco Product Manufacturing312112 | — | ◐ LIKELY ACTIVE |
| TVTennesse Valley Packing Co., Inc. | Columbia | TN | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| TBThe Butcher Shop Inc | Columbia | SC | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| TCThe Curators of the University of Missouri | Columbia | MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TFThe Farm a Cook Family Vineyard | Columbia | KY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| THThe Hearken Group LLC | Columbia | SC | Miscellaneous Manufacturing339950 | — | ◐ LIKELY ACTIVE |
| TWTommy Woodward, INC. | Columbia | MS | Fabricated Metal Product Manufacturing332710 | — | ◐ LIKELY ACTIVE |
| TCTown & Country 828 | Columbia | SC | Fabricated Metal Product Manufacturing332322 | 1-19 | ◐ LIKELY ACTIVE |
| TTrane | Columbia | SC | Wood Product Manufacturing321920 | 1-19 | ◐ LIKELY ACTIVE |
| TGTroy Gibson | Columbia | TN | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| UOUniversity of Missouri Meat Market | Columbia | MO | Food Manufacturing311611 | — | ◐ LIKELY ACTIVE |
| VOVineyards on the Scuppernong | Columbia | NC | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WCWaves Cider Company | Columbia | MO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WCWGS Columbia | Columbia | SC | Transportation Equipment Manufacturing336510 | 20-99 | ◐ LIKELY ACTIVE |
| WHWillis Ham Enterprises, LLC | Columbia | SC | Paper Manufacturing322291 | — | ◐ LIKELY ACTIVE |
| WWW. & W. Body Builders of Columbia, INC. | Columbia | SC | Transportation Equipment Manufacturing336110 | — | ◐ LIKELY ACTIVE |
| YHYankee Hill Winery | Columbia | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| ZZoetropolis | Columbia | PA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| ALAcepre, LLC | Columbia | SC | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |