| HJHancock Jaffe Laboratories INC | Irvine | CA | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| HLHandlworks, LLC | Irvine | CA | Transportation Equipment Manufacturing336320 | — | ◇ UNVERIFIED |
| HPHarit Patel | Irvine | CA | Transportation Equipment Manufacturing336612 | — | ◇ UNVERIFIED |
| HPHeritage Point | Irvine | CA | Nonmetallic Mineral Product Manufacturing327999 | — | ◇ UNVERIFIED |
| HIHeygears INC | Irvine | CA | Miscellaneous Manufacturing339114 | — | ◇ UNVERIFIED |
| HHouzz | Irvine | CA | Textile Mills313310 | — | ◇ UNVERIFIED |
| HSH S Printing Service | Irvine | CA | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| IVImex Vision | Irvine | CA | Food Manufacturing311999 | — | ◇ UNVERIFIED |
| ILImj LLC | Irvine | CA | Transportation Equipment Manufacturing336310 | — | ◇ UNVERIFIED |
| IDImperial Dade | Irvine | CA | Paper Manufacturing322299 | — | ◇ UNVERIFIED |
| IPImprimis Pharmaceuticals, INC. | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| IInari | Irvine | CA | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| IMInari Medical | Irvine | CA | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| ICInsulet Corporation | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| IPInternational Paper Company | Irvine | CA | Paper Manufacturing322211 | — | ◇ UNVERIFIED |
| ILIntregra Lifesciences | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| IBInvision Biomedical Group INC | Irvine | CA | Computer and Electronic Product Manufacturing334516 | — | ◇ UNVERIFIED |
| IIInvitro International | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| ILInvoy LLC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| ILInvoy LLC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| ITIo Therapeutics, INC. | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| IFIpr Fitness, Incorporated | Irvine | CA | Miscellaneous Manufacturing339920 | — | ◇ UNVERIFIED |
| ICIrvine Community Land Trust | Irvine | CA | Textile Mills313310 | — | ◇ UNVERIFIED |
| ICIrvine Company Office Properties | Irvine | CA | Beverage and Tobacco Product Manufacturing312230 | — | ◇ UNVERIFIED |
| IIIrvine, Infineon Technologies | Irvine | CA | Computer and Electronic Product Manufacturing334413 | — | ◇ UNVERIFIED |
| ILIrvine Lodging, LLC | Irvine | CA | Machinery Manufacturing333921 | — | ◇ UNVERIFIED |
| IIIvantis INC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| IIIvantis INC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| JPJac Printing | Irvine | CA | Plastics and Rubber Products Manufacturing326111 | — | ◇ UNVERIFIED |
| JWJacuzzi Whirlpool Bath | Irvine | CA | Plastics and Rubber Products Manufacturing326191 | — | ◇ UNVERIFIED |
| JRJames R Glidewell Dental Ceramics INC | Irvine | CA | Miscellaneous Manufacturing339116 | — | ◇ UNVERIFIED |
| JPJbw Properties | Irvine | CA | Transportation Equipment Manufacturing336350 | — | ◇ UNVERIFIED |
| JEJ E M Industries INC | Irvine | CA | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| JIJenavalve INC | Irvine | CA | Chemical Manufacturing325120 | — | ◇ UNVERIFIED |
| JPJenson Printing & Litho | Irvine | CA | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| JEJetline Engineering Inc, Div of Itw | Irvine | CA | Machinery Manufacturing333992 | — | ◇ UNVERIFIED |
| JCJmw Cabinets INC Dba Cabinets Plus | Irvine | CA | Wood Product Manufacturing321918 | — | ◇ UNVERIFIED |
| JKJohnston & Koper Group, Inc. | Irvine | CA | Fabricated Metal Product Manufacturing332913 | — | ◇ UNVERIFIED |
| JCJonset CORP Dba Sunset Property Svcs | Irvine | CA | Miscellaneous Manufacturing339994 | — | ◇ UNVERIFIED |
| KTKenny the Printer | Irvine | CA | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| KIKirchhan Ind INC | Irvine | CA | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| KHKMA Holdings, LLC | Irvine | CA | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| KLKnight LLC | Irvine | CA | Machinery Manufacturing333911 | — | ◇ UNVERIFIED |
| KLKnight LLC | Irvine | CA | Computer and Electronic Product Manufacturing334515 | — | ◇ UNVERIFIED |
| KKone | Irvine | CA | Textile Mills313310 | — | ◇ UNVERIFIED |
| LRLang Real Estate LLC | Irvine | CA | Computer and Electronic Product Manufacturing334417 | — | ◇ UNVERIFIED |
| LMLap Motorsports USA | Irvine | CA | Transportation Equipment Manufacturing336991 | — | ◇ UNVERIFIED |
| LSLa Supply Co/dba Label House | Irvine | CA | Paper Manufacturing322222 | — | ◇ UNVERIFIED |
| LTLeisure Time Packaging, Inc | Irvine | CA | Paper Manufacturing322230 | — | ◇ UNVERIFIED |
| LILensgen INC | Irvine | CA | Miscellaneous Manufacturing339115 | — | ◇ UNVERIFIED |