| FIFoldax INC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| FIFona International INC | Irvine | CA | Food Manufacturing311999 | — | ◇ UNVERIFIED |
| FMFrancisco Martinez | Irvine | CA | Machinery Manufacturing333921 | — | ◇ UNVERIFIED |
| FIFreedom Innovations LLC | Irvine | CA | Computer and Electronic Product Manufacturing334517 | — | ◇ UNVERIFIED |
| FFreshends | Irvine | CA | Paper Manufacturing322220 | — | ◇ UNVERIFIED |
| FSFrontier Systems | Irvine | CA | Transportation Equipment Manufacturing336411 | — | ◇ UNVERIFIED |
| FBFujifilm Biosciences | Irvine | CA | Chemical Manufacturing325414 | — | ◇ UNVERIFIED |
| GCGalan Cabinets, INC. | Irvine | CA | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| GSGatekeeper Systems INC | Irvine | CA | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| GIGentherm INC | Irvine | CA | Electrical Equipment, Appliance & Component Manufacturing335911 | — | ◇ UNVERIFIED |
| GIGiannico INC | Irvine | CA | Printing and Related Support Activities323113 | — | ◇ UNVERIFIED |
| GBGish Biomedical INC | Irvine | CA | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| GHGlam House Couture LLC | Irvine | CA | Apparel Manufacturing315990 | — | ◇ UNVERIFIED |
| GLGlidewell Laboratories | Irvine | CA | Miscellaneous Manufacturing339114 | — | ◇ UNVERIFIED |
| GLGlidewell Laboratories | Irvine | CA | Miscellaneous Manufacturing339116 | — | ◇ UNVERIFIED |
| GLGlidewell Laboratories | Irvine | CA | Miscellaneous Manufacturing339116 | — | ◇ UNVERIFIED |
| GRGlobal Rx Pharmacy & Compounding | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| GPGraphic Packaging International INC | Irvine | CA | Paper Manufacturing322211 | — | ◇ UNVERIFIED |
| GEGromax Enterprises Corporation | Irvine | CA | Petroleum and Coal Products Manufacturing324191 | — | ◇ UNVERIFIED |
| GFGrondorf Field Black & CO | Irvine | CA | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| GRGsm Retail | Irvine | CA | Apparel Manufacturing315212 | — | ◇ UNVERIFIED |
| HJHancock Jaffe Laboratories INC | Irvine | CA | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| HLHandlworks, LLC | Irvine | CA | Transportation Equipment Manufacturing336320 | — | ◇ UNVERIFIED |
| HPHarit Patel | Irvine | CA | Transportation Equipment Manufacturing336612 | — | ◇ UNVERIFIED |
| HPHeritage Point | Irvine | CA | Nonmetallic Mineral Product Manufacturing327999 | — | ◇ UNVERIFIED |
| HIHeygears INC | Irvine | CA | Miscellaneous Manufacturing339114 | — | ◇ UNVERIFIED |
| HCHinkle Contracting CORP - Irvine Asphalt Plant | Irvine | KY | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| HHouzz | Irvine | CA | Textile Mills313310 | — | ◇ UNVERIFIED |
| HSH S Printing Service | Irvine | CA | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| IVImex Vision | Irvine | CA | Food Manufacturing311999 | — | ◇ UNVERIFIED |
| ILImj LLC | Irvine | CA | Transportation Equipment Manufacturing336310 | — | ◇ UNVERIFIED |
| IDImperial Dade | Irvine | CA | Paper Manufacturing322299 | — | ◇ UNVERIFIED |
| IPImprimis Pharmaceuticals, INC. | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| IInari | Irvine | CA | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| IMInari Medical | Irvine | CA | Miscellaneous Manufacturing339112 | — | ◇ UNVERIFIED |
| ICInsulet Corporation | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| IPInternational Paper Company | Irvine | CA | Paper Manufacturing322211 | — | ◇ UNVERIFIED |
| ILIntregra Lifesciences | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| IBInvision Biomedical Group INC | Irvine | CA | Computer and Electronic Product Manufacturing334516 | — | ◇ UNVERIFIED |
| IIInvitro International | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| ILInvoy LLC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| ILInvoy LLC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| ITIo Therapeutics, INC. | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| IFIpr Fitness, Incorporated | Irvine | CA | Miscellaneous Manufacturing339920 | — | ◇ UNVERIFIED |
| ICIrvine Community Land Trust | Irvine | CA | Textile Mills313310 | — | ◇ UNVERIFIED |
| ICIrvine Company Office Properties | Irvine | CA | Beverage and Tobacco Product Manufacturing312230 | — | ◇ UNVERIFIED |
| IIIrvine, Infineon Technologies | Irvine | CA | Computer and Electronic Product Manufacturing334413 | — | ◇ UNVERIFIED |
| ILIrvine Lodging, LLC | Irvine | CA | Machinery Manufacturing333921 | — | ◇ UNVERIFIED |
| ILIsaacs Lumber INC | Irvine | KY | Wood Product Manufacturing321113 | — | ◇ UNVERIFIED |
| IIIvantis INC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |