| STSps Technologies LLC | Irvine | CA | Fabricated Metal Product Manufacturing332722 | — | ◐ LIKELY ACTIVE |
| S6Store 605 | Irvine | CA | Food Manufacturing311812 | 1-19 | ◐ LIKELY ACTIVE |
| SISummit Interconnect, INC. | Irvine | CA | Computer and Electronic Product Manufacturing334412 | — | ◐ LIKELY ACTIVE |
| TCTaber Company, Inc | Irvine | CA | Furniture and Related Product Manufacturing337212 | 100-499 | ◐ LIKELY ACTIVE |
| TPTarsus Pharmaceuticals INC | Irvine | CA | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| TLThaeta LLC | Irvine | CA | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| TJThe Joseph Company International, INC. | Irvine | CA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| UCUS331 CA Irvine | Irvine | CA | Miscellaneous Manufacturing339113 | 500+ | ◐ LIKELY ACTIVE |
| VVVena Vitals INC | Irvine | CA | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| VFVictory Foam, Inc. | Irvine | CA | Plastics and Rubber Products Manufacturing326150 | 100-499 | ◐ LIKELY ACTIVE |
| VGVillage Green Foods | Irvine | CA | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| XPXP Power - Irvine | Irvine | CA | Electrical Equipment, Appliance & Component Manufacturing335999 | 20-99 | ◐ LIKELY ACTIVE |
| ZCZOLL CMS TherOx | Irvine | CA | Computer and Electronic Product Manufacturing334510 | 20-99 | ◐ LIKELY ACTIVE |
| ATAstronics Test Systems INC | Irvine | CA | Computer and Electronic Product Manufacturing334515 | — | ◐ LIKELY ACTIVE |
| AIAquatec International INC | Irvine | CA | Machinery Manufacturing333911 | — | ◇ UNVERIFIED |
| BCBenchmark Cosmetic Laboratories | Irvine | CA | Chemical Manufacturing325620 | — | ◇ UNVERIFIED |
| CDCrenshaw Die and Manufacturing Corporation | Irvine | CA | Fabricated Metal Product Manufacturing332116 | — | ◇ UNVERIFIED |
| JCJmw Cabinets, INC. | Irvine | CA | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| 2H2040 Holdings, LLC | Irvine | CA | Textile Mills313310 | — | ◇ UNVERIFIED |
 3 Day Blinds Corporation | Irvine | CA | Furniture and Related Product Manufacturing337920 | — | ◇ UNVERIFIED |
| 3C3m Ceradyne INC a 3m Company | Irvine | CA | Nonmetallic Mineral Product Manufacturing327999 | — | ◇ UNVERIFIED |
| 9P9 Pasteur | Irvine | CA | Chemical Manufacturing325998 | — | ◇ UNVERIFIED |
| ANAbenmary Novel Enterprises INC. | Irvine | CA | Printing and Related Support Activities323113 | — | ◇ UNVERIFIED |
| ASAb Sciex, LLC | Irvine | CA | Computer and Electronic Product Manufacturing334516 | — | ◇ UNVERIFIED |
| ATAbstrax Tech INC | Irvine | CA | Food Manufacturing311999 | — | ◇ UNVERIFIED |
| ATAbstrax Tech INC | Irvine | CA | Chemical Manufacturing325620 | — | ◇ UNVERIFIED |
| AIAcclarent INC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| AIAcufocus INC | Irvine | CA | Miscellaneous Manufacturing339113 | — | ◇ UNVERIFIED |
| ABAdvanced Biocatalytics | Irvine | CA | Chemical Manufacturing325193 | — | ◇ UNVERIFIED |
| AGAguinaga Green INC | Irvine | CA | Chemical Manufacturing325314 | — | ◇ UNVERIFIED |
| ADAlbertsons Distribution Center | Irvine | CA | Food Manufacturing311411 | — | ◇ UNVERIFIED |
| ASAlcon Surgical INC | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| AIAllergan INC | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| AMAllergan Medical Optics | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| ALAllison Lie | Irvine | CA | Machinery Manufacturing333921 | — | ◇ UNVERIFIED |
| AOAmber Ornamental Iron | Irvine | CA | Fabricated Metal Product Manufacturing332323 | — | ◇ UNVERIFIED |
| ASAmetek Spectro Analytical Instruments INC | Irvine | CA | Computer and Electronic Product Manufacturing334516 | — | ◇ UNVERIFIED |
| AAmpronix | Irvine | CA | Computer and Electronic Product Manufacturing334118 | — | ◇ UNVERIFIED |
| ADAncerre Designs | Irvine | CA | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| APAnchen Pharmaceuticals, INC | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| APAnchen Pharmaceuticals, INC. | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| AMApi Mfg Facility Bausch Health Care | Irvine | CA | Chemical Manufacturing325412 | — | ◇ UNVERIFIED |
| AAArchytas Automation INC | Irvine | CA | Transportation Equipment Manufacturing336390 | — | ◇ UNVERIFIED |
| AIArdess International INC. | Irvine | CA | Food Manufacturing311999 | — | ◇ UNVERIFIED |
| AIArnabal International | Irvine | CA | Plastics and Rubber Products Manufacturing326220 | — | ◇ UNVERIFIED |
| ALArtidental Lab INC | Irvine | CA | Miscellaneous Manufacturing339116 | — | ◇ UNVERIFIED |
| ATAstronics Test Systems | Irvine | CA | Computer and Electronic Product Manufacturing334413 | — | ◇ UNVERIFIED |
| ACAtlas Copco Compressors- Irvine | Irvine | CA | Textile Mills313310 | — | ◇ UNVERIFIED |
| APAvon Protection Ceradyne | Irvine | CA | Apparel Manufacturing315990 | — | ◇ UNVERIFIED |
| ABAvrio Biopharmaceuticals, LLC | Irvine | CA | Chemical Manufacturing325411 | — | ◇ UNVERIFIED |
