| BFBloemer Food Sales Co. | Louisville | KY | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| BGBlue Giant Lifts, LLC | Louisville | KY | Machinery Manufacturing333998 | 20-99 | ◐ LIKELY ACTIVE |
| BLBluegrass Lawn and Garden INC | Louisville | KY | Machinery Manufacturing333112 | — | ◐ LIKELY ACTIVE |
| BDBreath Diagnostics, INC. | Louisville | KY | Chemical Manufacturing325413 | — | ▲ REPORTED CLOSED |
| BRBroad Run Vineyards | Louisville | KY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BSBroad St. | Louisville | OH | Fabricated Metal Product Manufacturing332996 | 20-99 | ◐ LIKELY ACTIVE |
| BBBrough Brothers Distillery | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| BBBrough Brothers Distillery Waterfront Park | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| BBrown -forman | Louisville | KY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BCBrown-forman Corporation | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| BRBuzzard's Roost Spirits, LLC | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| CICarbide Industries - Louisville Facility | Louisville | KY | Chemical Manufacturing325180 | 100-499 | ◐ LIKELY ACTIVE |
| COCarter of Kentucky LLC | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| CWChampion Window of Louisville | Louisville | KY | Plastics and Rubber Products Manufacturing326121 | 1-19 | ◐ LIKELY ACTIVE |
| CICimarc, INC. | Louisville | KY | Miscellaneous Manufacturing339950 | — | ◐ LIKELY ACTIVE |
| CFClark Foam - Louisville | Louisville | KY | Plastics and Rubber Products Manufacturing326112 | 1-19 | ◐ LIKELY ACTIVE |
| CRCMC Rebar Louisville | Louisville | KY | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| CPCoastal Processing, LLC | Louisville | GA | Food Manufacturing311615 | — | ◐ LIKELY ACTIVE |
| CIContractorsHeaven.com, Inc. | Louisville | KY | Machinery Manufacturing333248 | 20-99 | ◐ LIKELY ACTIVE |
| CSCornerstone Specialty Wood Products | Louisville | KY | Fabricated Metal Product Manufacturing332999 | 20-99 | ◐ LIKELY ACTIVE |
Crane 1 Services - Louisville | Louisville | KY | Machinery Manufacturing333923 | 1-19 | ◐ LIKELY ACTIVE |
| CGCreation Gardens | Louisville | KY | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| CPCrestwood Plant 900 | Louisville | KY | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| CLCrggov LLC | Louisville | KY | Machinery Manufacturing333993 | — | ◐ LIKELY ACTIVE |
| CCCulture Club LLC | Louisville | CO | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CFCustom Food Solutions, LLC | Louisville | KY | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| DDafco | Louisville | KY | Primary Metal Manufacturing331512 | 20-99 | ◐ LIKELY ACTIVE |
| DADafco Aerospace | Louisville | KY | Primary Metal Manufacturing331512 | 20-99 | ◐ LIKELY ACTIVE |
| DIDakkota Integrated Systems, LLC. Louisville | Louisville | KY | Transportation Equipment Manufacturing336330 | 100-499 | ◐ LIKELY ACTIVE |
| DIDana Inc. (Louisville Facility) | Louisville | KY | Transportation Equipment Manufacturing336350 | 100-499 | ◐ LIKELY ACTIVE |
| DDanfoss | Louisville | KY | Fabricated Metal Product Manufacturing332410 | 20-99 | ◐ LIKELY ACTIVE |
| DCDant Clayton Corporation | Louisville | KY | Fabricated Metal Product Manufacturing332999 | — | ◐ LIKELY ACTIVE |
| DFDawn Food Products - Louisville Manufacturing | Louisville | KY | Food Manufacturing311999 | 100-499 | ◐ LIKELY ACTIVE |
| DWDD Williamson GSC | Louisville | KY | Food Manufacturing311942 | 20-99 | ◐ LIKELY ACTIVE |
| DADesicorp Advanced Materials, INC. | Louisville | KY | Plastics and Rubber Products Manufacturing326112 | — | ◐ LIKELY ACTIVE |
| DIDesicorp, INC. | Louisville | KY | Chemical Manufacturing325414 | — | ◐ LIKELY ACTIVE |
| DNDiageo NAM-Stitzel Weller | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | 20-99 | ◐ LIKELY ACTIVE |
| DSDistilled Spirits Epicenter, LLC | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| DADistillery America LLC | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| DMDiversified Metals | Louisville | KY | Fabricated Metal Product Manufacturing332323 | 20-99 | ◐ LIKELY ACTIVE |
| DCDownstream & Chemicals - Louisville, KY Lubricants Plant | Louisville | KY | Petroleum and Coal Products Manufacturing324191 | 20-99 | ◐ LIKELY ACTIVE |
| DSDuPont Specialty Products USA, LLC | Louisville | KY | Chemical Manufacturing325120 | 20-99 | ◐ LIKELY ACTIVE |
| DDynacraft | Louisville | KY | Transportation Equipment Manufacturing336350 | 500+ | ◐ LIKELY ACTIVE |
| ECEaton Corporation | Louisville | KY | Electrical Equipment, Appliance & Component Manufacturing335311 | — | ◐ LIKELY ACTIVE |
| EAECKART America - Louisville | Louisville | KY | Primary Metal Manufacturing331314 | 20-99 | ◐ LIKELY ACTIVE |
| ELEndonavis LLC | Louisville | KY | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| ELEnovapremier LLC | Louisville | KY | Transportation Equipment Manufacturing336390 | 20-99 | ◐ LIKELY ACTIVE |
| EDEquipment Depot Kentucky, Inc. - Louisville | Louisville | KY | Machinery Manufacturing333924 | 20-99 | ◐ LIKELY ACTIVE |
| FCFalls City Limb & Brace CO INC | Louisville | KY | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| FDFarmer's Distillery, LLC | Louisville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |