| HHistosonics | Plymouth | MN | Computer and Electronic Product Manufacturing334510 | 100-499 | ◐ LIKELY ACTIVE |
| LILaplace Interventional | Plymouth | MN | Miscellaneous Manufacturing339112 | 1-19 | ◐ LIKELY ACTIVE |
| LPLoc Pac INC | Plymouth | MI | Fabricated Metal Product Manufacturing332721 | — | ◐ LIKELY ACTIVE |
| LMLundell Mfg CORP | Plymouth | MN | Fabricated Metal Product Manufacturing332116 | 20-99 | ◐ LIKELY ACTIVE |
| MMedivators | Plymouth | MN | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| MAMedtronic Apv | Plymouth | MN | Machinery Manufacturing333911 | — | ◐ LIKELY ACTIVE |
| NLNatureworks LLC | Plymouth | MN | Miscellaneous Manufacturing339112 | 100-499 | ◐ LIKELY ACTIVE |
| OROzinga Ready-mix Concrete Plymouth | Plymouth | IN | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| PIPneumadyne INC | Plymouth | MN | Fabricated Metal Product Manufacturing332911 | — | ◐ LIKELY ACTIVE |
| AMAc5 Med - Plymouth | Plymouth | MN | Miscellaneous Manufacturing339112 | 100-499 | ◐ LIKELY ACTIVE |
| ALADIENT LLC Headquarters | Plymouth | MI | Transportation Equipment Manufacturing336360 | 500+ | ◐ LIKELY ACTIVE |
| AAAisin Aftermarket & Service of America Inc. (Cleat) | Plymouth | MI | Transportation Equipment Manufacturing336350 | 1-19 | ◐ LIKELY ACTIVE |
| AAAisin Aftermarket & Service of America Inc. (KSE) | Plymouth | MI | Transportation Equipment Manufacturing336350 | 100-499 | ◐ LIKELY ACTIVE |
| AAAisin Aftermarket & Service of America Inc. (KSW) | Plymouth | MI | Transportation Equipment Manufacturing336350 | 20-99 | ◐ LIKELY ACTIVE |
| AIAK Industries Administration | Plymouth | IN | Plastics and Rubber Products Manufacturing326199 | 1-19 | ◐ LIKELY ACTIVE |
| AIAK Industries Plant 2 | Plymouth | IN | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| AIAK Industries Plant 4 | Plymouth | IN | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| AMAllegra Marketing Print Mail | Plymouth | MI | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| ADAmadoras Del Vino LLC | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| AIAmerican Insulated Glass LLC - Detroit | Plymouth | MI | Nonmetallic Mineral Product Manufacturing327215 | 20-99 | ◐ LIKELY ACTIVE |
| ATAmerilab Technologies, Inc. | Plymouth | MN | Chemical Manufacturing325411 | 100-499 | ◐ LIKELY ACTIVE |
| AWArdaven Winery | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| ATArgent Tape and Label | Plymouth | MI | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| ATAvl Tsi | Plymouth | MI | Computer and Electronic Product Manufacturing334516 | 100-499 | ◐ LIKELY ACTIVE |
| BEBakehouse Enterprises, LLC, DBA Boxford Bakehouse | Plymouth | MA | Food Manufacturing311999 | — | ◐ LIKELY ACTIVE |
| BLBearded Lamb Brewing Company | Plymouth | MI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BVBelledor Vineyards | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BPBildon Parts and Service | Plymouth | MI | Machinery Manufacturing333310 | 20-99 | ◐ LIKELY ACTIVE |
| BWBorjon Winery | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BNBrembo North America | Plymouth | MI | Transportation Equipment Manufacturing336340 | 100-499 | ◐ LIKELY ACTIVE |
| CSCambria Surfaces Plymouth | Plymouth | MN | Nonmetallic Mineral Product Manufacturing327991 | 20-99 | ◐ LIKELY ACTIVE |
| CCampus | Plymouth | MN | Electrical Equipment, Appliance & Component Manufacturing335314 | 100-499 | ◐ LIKELY ACTIVE |
| CMCasino Mine Ranch | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CMCasino Mine Ranch | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CCCDF Corporation 57 | Plymouth | MA | Plastics and Rubber Products Manufacturing326111 | 20-99 | ◐ LIKELY ACTIVE |
| C8Cellar 849 | Plymouth | MI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CCCertainTeed Ceilings - Plymouth | Plymouth | WI | Nonmetallic Mineral Product Manufacturing327420 | 20-99 | ◐ LIKELY ACTIVE |
| CDC.g. Di Arie Vineyard & Winery | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CHChicory Hill Vineyards | Plymouth | WI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CCimline | Plymouth | MN | Machinery Manufacturing333120 | 1-19 | ◐ LIKELY ACTIVE |
| CVCinko Vineyards | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CPCoherent - Plymouth | Plymouth | MI | Machinery Manufacturing333517 | 20-99 | ◐ LIKELY ACTIVE |
| CMComplexus Medical Plymouth | Plymouth | IN | Miscellaneous Manufacturing339112 | 20-99 | ◐ LIKELY ACTIVE |
| CVCooper Vineyards, LLC | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CPCorrugated Packaging Plymouth FSP | Plymouth | IN | Paper Manufacturing322211 | 100-499 | ◐ LIKELY ACTIVE |
| DIDeltak Inc | Plymouth | MN | Fabricated Metal Product Manufacturing332410 | 20-99 | ◐ LIKELY ACTIVE |
| DTDiamond Tool Manufacturing Inc | Plymouth | MI | Machinery Manufacturing333515 | 20-99 | ◐ LIKELY ACTIVE |
| DWDillian Wines | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| DWDirty Water Distillery, LLC | Plymouth | MA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| DZDobra Zemlja | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |