| ATAtlas Tube- Plymouth Plant | Plymouth | MI | Primary Metal Manufacturing331210 | 20-99 | ◐ LIKELY ACTIVE |
| BOBrugola Oeb Industriale USA INC | Plymouth | MI | Fabricated Metal Product Manufacturing332722 | 20-99 | ◐ LIKELY ACTIVE |
| CIChrysan Industries | Plymouth | MI | Petroleum and Coal Products Manufacturing324191 | 20-99 | ◐ LIKELY ACTIVE |
| CACygnet Automated Cleaning LLC | Plymouth | MI | Chemical Manufacturing325510 | 20-99 | ◐ LIKELY ACTIVE |
| CACygnet Automated Cleaning, LLC | Plymouth | MI | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| DIDadco INC | Plymouth | MI | Fabricated Metal Product Manufacturing332912 | 100-499 | ◐ LIKELY ACTIVE |
| FAFuyao Automotive North America | Plymouth | MI | Nonmetallic Mineral Product Manufacturing327212 | 100-499 | ◐ LIKELY ACTIVE |
| LELink Engineering | Plymouth | MI | Machinery Manufacturing333518 | 100-499 | ◐ LIKELY ACTIVE |
Optimal Electric Vehicles LLC | Plymouth | MI | Transportation Equipment Manufacturing336211 | — | ◐ LIKELY ACTIVE |
| APAction Printech INC | Plymouth | MI | Printing and Related Support Activities323110 | — | ◐ LIKELY ACTIVE |
| EEE & E Manufacturing Company INC | Plymouth | MI | Fabricated Metal Product Manufacturing332722 | 100-499 | ◐ LIKELY ACTIVE |
| OMOerlikon Metco - Plymouth | Plymouth | MI | Primary Metal Manufacturing331492 | 20-99 | ◐ LIKELY ACTIVE |
| PHParker Hannifin Cylinder-plymouth Facility | Plymouth | MI | Fabricated Metal Product Manufacturing332912 | — | ◐ LIKELY ACTIVE |
| SPSun Plastic Coating CO | Plymouth | MI | Fabricated Metal Product Manufacturing332812 | — | ◐ LIKELY ACTIVE |
| TITram INC | Plymouth | MI | Transportation Equipment Manufacturing336320 | 100-499 | ◐ LIKELY ACTIVE |
| WCWebasto Convertibles | Plymouth | MI | Transportation Equipment Manufacturing336390 | 100-499 | ◐ LIKELY ACTIVE |
| WRWebasto Roof Systems, INC | Plymouth | MI | Transportation Equipment Manufacturing336390 | 500+ | ◐ LIKELY ACTIVE |
| LPLoc Pac INC | Plymouth | MI | Fabricated Metal Product Manufacturing332721 | — | ◐ LIKELY ACTIVE |
| ALADIENT LLC Headquarters | Plymouth | MI | Transportation Equipment Manufacturing336360 | 500+ | ◐ LIKELY ACTIVE |
| AAAisin Aftermarket & Service of America Inc. (Cleat) | Plymouth | MI | Transportation Equipment Manufacturing336350 | 1-19 | ◐ LIKELY ACTIVE |
| AAAisin Aftermarket & Service of America Inc. (KSE) | Plymouth | MI | Transportation Equipment Manufacturing336350 | 100-499 | ◐ LIKELY ACTIVE |
| AAAisin Aftermarket & Service of America Inc. (KSW) | Plymouth | MI | Transportation Equipment Manufacturing336350 | 20-99 | ◐ LIKELY ACTIVE |
| AMAllegra Marketing Print Mail | Plymouth | MI | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| AIAmerican Insulated Glass LLC - Detroit | Plymouth | MI | Nonmetallic Mineral Product Manufacturing327215 | 20-99 | ◐ LIKELY ACTIVE |
| ATArgent Tape and Label | Plymouth | MI | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| ATAvl Tsi | Plymouth | MI | Computer and Electronic Product Manufacturing334516 | 100-499 | ◐ LIKELY ACTIVE |
| BLBearded Lamb Brewing Company | Plymouth | MI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| BPBildon Parts and Service | Plymouth | MI | Machinery Manufacturing333310 | 20-99 | ◐ LIKELY ACTIVE |
| BNBrembo North America | Plymouth | MI | Transportation Equipment Manufacturing336340 | 100-499 | ◐ LIKELY ACTIVE |
| C8Cellar 849 | Plymouth | MI | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CCClips & Clamps Industries | Plymouth | MI | Transportation Equipment Manufacturing336370 | 20-99 | ◐ LIKELY ACTIVE |
| CPCoherent - Plymouth | Plymouth | MI | Machinery Manufacturing333517 | 20-99 | ◐ LIKELY ACTIVE |
| DTDiamond Tool Manufacturing Inc | Plymouth | MI | Machinery Manufacturing333515 | 20-99 | ◐ LIKELY ACTIVE |
| FFreudenberg-NOK | Plymouth | MI | Miscellaneous Manufacturing339991 | 100-499 | ◐ LIKELY ACTIVE |
| HMHavis MI | Plymouth | MI | Computer and Electronic Product Manufacturing334118 | 20-99 | ◐ LIKELY ACTIVE |
| IPImage360 Plymouth | Plymouth | MI | Miscellaneous Manufacturing339950 | 1-19 | ◐ LIKELY ACTIVE |
| KIKimprint, Inc. | Plymouth | MI | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| KIKyocera International Incorporated-Display | Plymouth | MI | Computer and Electronic Product Manufacturing334419 | 20-99 | ◐ LIKELY ACTIVE |
| LPLoc Performance Products LLC | Plymouth | MI | Transportation Equipment Manufacturing336992 | — | ◐ LIKELY ACTIVE |
| LMLuca Mariano Distillery LLC | Plymouth | MI | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| MMMacLean Master EAST | Plymouth | MI | Fabricated Metal Product Manufacturing332721 | 100-499 | ◐ LIKELY ACTIVE |
| MMMacLean Master WEST | Plymouth | MI | Fabricated Metal Product Manufacturing332721 | 100-499 | ◐ LIKELY ACTIVE |
| MOMichigan Office | Plymouth | MI | Transportation Equipment Manufacturing336320 | 20-99 | ◐ LIKELY ACTIVE |
| PMPatriot Manufacturing, LLC. | Plymouth | MI | Fabricated Metal Product Manufacturing332710 | 20-99 | ◐ LIKELY ACTIVE |
| PIPerceptron Inc. | Plymouth | MI | Computer and Electronic Product Manufacturing334513 | 100-499 | ◐ LIKELY ACTIVE |
| PPPlastipak Packaging- Global Business & Technology Center | Plymouth | MI | Plastics and Rubber Products Manufacturing326160 | 100-499 | ◐ LIKELY ACTIVE |
| PPlymouth | Plymouth | MI | Food Manufacturing311930 | 20-99 | ◐ LIKELY ACTIVE |
| PMPlymouth, Mi | Plymouth | MI | Paper Manufacturing322211 | 100-499 | ◐ LIKELY ACTIVE |
| PRPlymouth R&D | Plymouth | MI | Transportation Equipment Manufacturing336211 | 20-99 | ◐ LIKELY ACTIVE |
| SGSalter Group, L.l.c. | Plymouth | MI | Machinery Manufacturing333612 | — | ◐ LIKELY ACTIVE |