| AIAacron INC | Plymouth | MN | Fabricated Metal Product Manufacturing332813 | 20-99 | ◐ LIKELY ACTIVE |
| ATAtlas Tube- Plymouth Plant | Plymouth | MI | Primary Metal Manufacturing331210 | 20-99 | ◐ LIKELY ACTIVE |
| AIAk Industries, INC. Plant 3 | Plymouth | IN | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| BIBomarko, INC. | Plymouth | IN | Paper Manufacturing322220 | 20-99 | ◐ LIKELY ACTIVE |
| BOBrugola Oeb Industriale USA INC | Plymouth | MI | Fabricated Metal Product Manufacturing332722 | 20-99 | ◐ LIKELY ACTIVE |
| CIChrysan Industries | Plymouth | MI | Petroleum and Coal Products Manufacturing324191 | 20-99 | ◐ LIKELY ACTIVE |
| CTComposite Technology Assemblies | Plymouth | IN | Plastics and Rubber Products Manufacturing326191 | — | ◐ LIKELY ACTIVE |
| CACygnet Automated Cleaning LLC | Plymouth | MI | Chemical Manufacturing325510 | 20-99 | ◐ LIKELY ACTIVE |
| CACygnet Automated Cleaning, LLC | Plymouth | MI | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| DIDadco INC | Plymouth | MI | Fabricated Metal Product Manufacturing332912 | 100-499 | ◐ LIKELY ACTIVE |
| DPDomtar Paper CO LLC Plymouth Mill | Plymouth | NC | Paper Manufacturing322110 | — | ◐ LIKELY ACTIVE |
| ESElectropolishing Systems | Plymouth | MA | Fabricated Metal Product Manufacturing332710 | 20-99 | ◐ LIKELY ACTIVE |
| FAFuyao Automotive North America | Plymouth | MI | Nonmetallic Mineral Product Manufacturing327212 | 100-499 | ◐ LIKELY ACTIVE |
| HTHoosier Tire & Rubber CORP -plant 2 | Plymouth | IN | Plastics and Rubber Products Manufacturing326211 | — | ◐ LIKELY ACTIVE |
| LILinfor INC. | Plymouth | MN | Fabricated Metal Product Manufacturing332912 | 100-499 | ◐ LIKELY ACTIVE |
| LELink Engineering | Plymouth | MI | Machinery Manufacturing333518 | 100-499 | ◐ LIKELY ACTIVE |
| MUMaax US CORP | Plymouth | IN | Plastics and Rubber Products Manufacturing326191 | — | ◐ LIKELY ACTIVE |
| MPMorris Packaging LLC | Plymouth | MN | Printing and Related Support Activities323111 | 100-499 | ◐ LIKELY ACTIVE |
| NSNucor Steel - a Div of Nucor CORP | Plymouth | UT | Primary Metal Manufacturing331110 | — | ◐ LIKELY ACTIVE |
| PFPlymouth Foundry Incorporated | Plymouth | IN | Primary Metal Manufacturing331511 | 20-99 | ◐ LIKELY ACTIVE |
| ZNZentis North America | Plymouth | IN | Food Manufacturing311411 | — | ◐ LIKELY ACTIVE |
Marlow Ropes INC | Plymouth | MA | Textile Product Mills314994 | — | ◐ LIKELY ACTIVE |
| MTMillennium Technologies LLC | Plymouth | WI | Fabricated Metal Product Manufacturing332710 | — | ◐ LIKELY ACTIVE |
Optimal Electric Vehicles LLC | Plymouth | MI | Transportation Equipment Manufacturing336211 | — | ◐ LIKELY ACTIVE |
| 1W1620 Winery Corporation | Plymouth | MA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| APAction Printech INC | Plymouth | MI | Printing and Related Support Activities323110 | — | ◐ LIKELY ACTIVE |
| ATAljon Tool INC | Plymouth | MN | Fabricated Metal Product Manufacturing332322 | 20-99 | ◐ LIKELY ACTIVE |
| BGBrand Graphic Solutions, INC | Plymouth | PA | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| CAControl Assemblies Company | Plymouth | MN | Computer and Electronic Product Manufacturing334220 | 20-99 | ◐ LIKELY ACTIVE |
| DPDanfoss Power Solutions Plymouth | Plymouth | MN | Electrical Equipment, Appliance & Component Manufacturing335999 | 100-499 | ◐ LIKELY ACTIVE |
| DWDiversified Wood Products, INC. | Plymouth | NC | Wood Product Manufacturing321920 | 20-99 | ◐ LIKELY ACTIVE |
| EEE & E Manufacturing Company INC | Plymouth | MI | Fabricated Metal Product Manufacturing332722 | 100-499 | ◐ LIKELY ACTIVE |
| EMEntellus Medical | Plymouth | MN | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| GEGarlock Equipment CO | Plymouth | MN | Machinery Manufacturing333120 | 20-99 | ◐ LIKELY ACTIVE |
| HSHershey Salty Snacks - Plymouth Plant | Plymouth | IN | Food Manufacturing311821 | — | ◐ LIKELY ACTIVE |
| IFIndependent Fermentations Brewing | Plymouth | MA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| KVKarmere Vineyards & Winery LLC | Plymouth | CA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| OMOerlikon Metco - Plymouth | Plymouth | MI | Primary Metal Manufacturing331492 | 20-99 | ◐ LIKELY ACTIVE |
| PHParker Hannifin Cylinder-plymouth Facility | Plymouth | MI | Fabricated Metal Product Manufacturing332912 | — | ◐ LIKELY ACTIVE |
| PLPdl Laboratory, INC | Plymouth | MA | Miscellaneous Manufacturing339116 | — | ◐ LIKELY ACTIVE |
| PAPlymouth-3mus-in Aearo | Plymouth | IN | Machinery Manufacturing333314 | 1-19 | ◐ LIKELY ACTIVE |
| PFPlymouth Foam INC | Plymouth | WI | Plastics and Rubber Products Manufacturing326140 | — | ◐ LIKELY ACTIVE |
| PIPregis Innovative Packaging INC | Plymouth | IN | Plastics and Rubber Products Manufacturing326140 | — | ◐ LIKELY ACTIVE |
| PMPromed Molded Products - 23rd Ave | Plymouth | MN | Plastics and Rubber Products Manufacturing326199 | 20-99 | ◐ LIKELY ACTIVE |
| RDRed Devil Equipment Company | Plymouth | MN | Machinery Manufacturing333249 | 20-99 | ◐ LIKELY ACTIVE |
Seachange Printing & Marketing Services LLC | Plymouth | MN | Printing and Related Support Activities323110 | 100-499 | ◐ LIKELY ACTIVE |
| SSStone Source INC | Plymouth | MN | Nonmetallic Mineral Product Manufacturing327991 | 20-99 | ◐ LIKELY ACTIVE |
| SPSun Plastic Coating CO | Plymouth | MI | Fabricated Metal Product Manufacturing332812 | — | ◐ LIKELY ACTIVE |
| TITram INC | Plymouth | MI | Transportation Equipment Manufacturing336320 | 100-499 | ◐ LIKELY ACTIVE |
| ULUpsher-Smith Laboratories, LLC Plymouth | Plymouth | MN | Chemical Manufacturing325412 | 100-499 | ◐ LIKELY ACTIVE |