| FWFeuillerat Welding, LLC | Rapid City | SD | Machinery Manufacturing333248 | — | ◐ LIKELY ACTIVE |
| FWFirehouse Wine Cellars | Rapid City | SD | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| FPForest Products Distributors, INC. | Rapid City | SD | Wood Product Manufacturing321113 | — | ◐ LIKELY ACTIVE |
| HPHills Products Group, INC. | Rapid City | SD | Wood Product Manufacturing321114 | — | ◐ LIKELY ACTIVE |
| HIHorner Industries INC. | Rapid City | SD | Fabricated Metal Product Manufacturing332999 | — | ◐ LIKELY ACTIVE |
| ITImmutrix Therapeutics, INC. | Rapid City | SD | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| PLPete Lien & Sons Rapid City Central Mix | Rapid City | SD | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| PDProSmiles Dental Studio | Rapid City | SD | Miscellaneous Manufacturing339116 | 20-99 | ◐ LIKELY ACTIVE |
| RRapcp | Rapid City | SD | Nonmetallic Mineral Product Manufacturing327332 | 20-99 | ◐ LIKELY ACTIVE |
| RCRapid City (1016) | Rapid City | SD | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| RCRapid City, USA | Rapid City | SD | Computer and Electronic Product Manufacturing334511 | 20-99 | ◐ LIKELY ACTIVE |
| SRSimon - Rapid City Concrete Plant | Rapid City | SD | Nonmetallic Mineral Product Manufacturing327320 | 1-19 | ◐ LIKELY ACTIVE |
| SDSteed Diane | Rapid City | MI | Transportation Equipment Manufacturing336992 | — | ◐ LIKELY ACTIVE |
| TTTemperature Technology, INC. | Rapid City | SD | Computer and Electronic Product Manufacturing334512 | — | ◐ LIKELY ACTIVE |
| TETorres Enterprises LLC | Rapid City | SD | Printing and Related Support Activities323113 | — | ◐ LIKELY ACTIVE |
| UWUplifted Winery | Rapid City | SD | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| WMWall Meats Rapid | Rapid City | SD | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| WWcm | Rapid City | SD | Fabricated Metal Product Manufacturing332321 | 20-99 | ◐ LIKELY ACTIVE |
| WPWL Plastics - Rapid City | Rapid City | SD | Plastics and Rubber Products Manufacturing326122 | 20-99 | ◐ LIKELY ACTIVE |
| ZBZymurcracy Beer Company | Rapid City | SD | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| AHAiden Holdings LLC | Rapid City | SD | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| AEApex Electric & Sign LLC | Rapid City | SD | Miscellaneous Manufacturing339950 | — | ◇ UNVERIFIED |
| BHBlack Hills Railings LLC | Rapid City | SD | Fabricated Metal Product Manufacturing332323 | — | ◇ UNVERIFIED |
| BFBranson Family Holdings LLC | Rapid City | SD | Primary Metal Manufacturing331210 | — | ◇ UNVERIFIED |
| CNCupcakes N' Schmitt LLC | Rapid City | SD | Food Manufacturing311811 | — | ◇ UNVERIFIED |
| DBDakota Biochar LLC | Rapid City | SD | Chemical Manufacturing325194 | — | ◇ UNVERIFIED |
| DBDakota Butcher - Rapid City, Inc. | Rapid City | SD | Food Manufacturing311615 | — | ◇ UNVERIFIED |
| FAFM Acquisition LLC | Rapid City | SD | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| FCFormer Creative Marblecast Manufacturing Plant | Rapid City | SD | Plastics and Rubber Products Manufacturing326191 | — | ◇ UNVERIFIED |
| JSJewelryMonk Studio and Training Center Jewelry by DeCory | Rapid City | SD | Miscellaneous Manufacturing339910 | — | ◇ UNVERIFIED |
| JKJ.M. Kingsbury Family Brewing Co. | Rapid City | SD | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| KPK & P LLC | Rapid City | SD | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| KKugler | Rapid City | SD | Chemical Manufacturing325311 | — | ◇ UNVERIFIED |
| OSOEM Solutions Inc | Rapid City | SD | Computer and Electronic Product Manufacturing334419 | — | ◇ UNVERIFIED |
| RCRapid City Apb | Rapid City | SD | Chemical Manufacturing325998 | — | ◇ UNVERIFIED |
| RLRizco, LLC | Rapid City | SD | Electrical Equipment, Appliance & Component Manufacturing335311 | — | ◇ UNVERIFIED |
| SMSturgis Meats LLC | Rapid City | SD | Food Manufacturing311611 | — | ◇ UNVERIFIED |
| TAT and K Hunting Gear LLC | Rapid City | SD | Apparel Manufacturing315990 | — | ◇ UNVERIFIED |
| TGTwo Gals and a Guy LLC | Rapid City | SD | Food Manufacturing311811 | — | ◇ UNVERIFIED |
| WCWest Central Manufacturing | Rapid City | SD | Furniture and Related Product Manufacturing337215 | — | ◇ UNVERIFIED |