| KSKi Shelbyville Truss | Shelbyville | KY | Wood Product Manufacturing321215 | 20-99 | ◐ LIKELY ACTIVE |
| KIKnauf Insulation Plant 3 | Shelbyville | IN | Nonmetallic Mineral Product Manufacturing327993 | 100-499 | ◐ LIKELY ACTIVE |
| MSMetal Solutions - Indianapolis | Shelbyville | IN | Fabricated Metal Product Manufacturing332311 | 20-99 | ◐ LIKELY ACTIVE |
| NGNearest Green Distillery, INC. | Shelbyville | TN | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| NANifco America Corporation KY | Shelbyville | KY | Plastics and Rubber Products Manufacturing326199 | 100-499 | ◐ LIKELY ACTIVE |
| PPPegasus Packaging, LLC | Shelbyville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| PUPK U.S.A. Inc | Shelbyville | IN | Transportation Equipment Manufacturing336370 | 100-499 | ◐ LIKELY ACTIVE |
| SPShelbyville Packaging Operations Center | Shelbyville | TN | Miscellaneous Manufacturing339940 | 100-499 | ◐ LIKELY ACTIVE |
| SRSmith Run Farms LLC | Shelbyville | KY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TWTalon Winery | Shelbyville | KY | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| TCTaylor Comms - Shelbyville IN - 0116-INSH1 | Shelbyville | IN | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |
| TBThe Blending House | Shelbyville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| TMThe Maven Distillery | Shelbyville | KY | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| TSTriumph - Shelbyville, IN | Shelbyville | IN | Transportation Equipment Manufacturing336413 | 20-99 | ◐ LIKELY ACTIVE |
| TFTyson Foods, Inc. | Shelbyville | TN | Food Manufacturing311615 | — | ◐ LIKELY ACTIVE |
| VRvoestalpine Roll Forming Corporation Aerospace Division | Shelbyville | KY | Fabricated Metal Product Manufacturing332114 | 20-99 | ◐ LIKELY ACTIVE |
| VRvoestalpine Roll Forming Corporation Commercial Division | Shelbyville | KY | Fabricated Metal Product Manufacturing332114 | 100-499 | ◐ LIKELY ACTIVE |