| NSNorfolk Southern Railway | Spartanburg | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| ODOshkosh Defense LLC | Spartanburg | SC | Transportation Equipment Manufacturing336110 | — | ◐ LIKELY ACTIVE |
| PMPhoto Marker Ii Incorporated | Spartanburg | SC | Paper Manufacturing322220 | — | ◐ LIKELY ACTIVE |
| PSPolar Service Centers | Spartanburg | SC | Machinery Manufacturing333924 | — | ◐ LIKELY ACTIVE |
| PPProtech Powder Coatings INC | Spartanburg | SC | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| SMSantolubes Manufacturing LLC | Spartanburg | SC | Chemical Manufacturing325110 | 20-99 | ◐ LIKELY ACTIVE |
| TATegrant Alloyd Brands INC Gw Remediation | Spartanburg | SC | Paper Manufacturing322299 | — | ◐ LIKELY ACTIVE |
| CSCooper Standard | Spartanburg | SC | Plastics and Rubber Products Manufacturing326121 | — | ◐ LIKELY ACTIVE |
| KCKohler CO. - Spartanburg Plant | Spartanburg | SC | Plastics and Rubber Products Manufacturing326191 | — | ◐ LIKELY ACTIVE |
| MCMilliken Cotton Blossom-plant | Spartanburg | SC | Textile Mills313110 | — | ◐ LIKELY ACTIVE |
 Pacific Industrial Development Corporation | Spartanburg | SC | Chemical Manufacturing325180 | — | ◐ LIKELY ACTIVE |
| SWSouthern Wood Piedmont CO | Spartanburg | SC | Wood Product Manufacturing321114 | — | ◐ LIKELY ACTIVE |
| AEAdvanced Environmental Options INC | Spartanburg | SC | Chemical Manufacturing325199 | — | ◇ UNVERIFIED |
| AFAmerican Fast Print-closed | Spartanburg | SC | Textile Mills313310 | — | ◇ UNVERIFIED |
| AAAsphalt Associates | Spartanburg | SC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| BBBaker & Baker | Spartanburg | SC | Food Manufacturing311421 | — | ◇ UNVERIFIED |
| BMBmc Manufacturing | Spartanburg | SC | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| CCChapman Concrete Products Incorporated | Spartanburg | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CCCmc - Commercial Metals CO Recycling | Spartanburg | SC | Primary Metal Manufacturing331000 | — | ◇ UNVERIFIED |
| CSConcrete Supply CO LLC - Spartanburg National | Spartanburg | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CSConcrete Supply CO LLC - Spartan Ent Temp | Spartanburg | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| CIContec INC. Wingo Park Location | Spartanburg | SC | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| CGCopac Global Packaging INC | Spartanburg | SC | Paper Manufacturing322212 | — | ◇ UNVERIFIED |
| CCCrown Cork and Seal Company Incorporated | Spartanburg | SC | Fabricated Metal Product Manufacturing332431 | — | ◇ UNVERIFIED |
| FCFlint Cps Inks North America LLC | Spartanburg | SC | Chemical Manufacturing325910 | — | ◇ UNVERIFIED |
| FIFlint Ink:cedar Springs Avenue Plant | Spartanburg | SC | Chemical Manufacturing325510 | — | ◇ UNVERIFIED |
| GCGeorgia-pacific Corrugated LLC - Spartanburg Facility | Spartanburg | SC | Paper Manufacturing322211 | — | ◇ UNVERIFIED |
| GSGoodyear Spartanburg | Spartanburg | SC | Plastics and Rubber Products Manufacturing326211 | — | ◇ UNVERIFIED |
| GDGries Dynacast Company | Spartanburg | SC | Fabricated Metal Product Manufacturing332812 | — | ◇ UNVERIFIED |
| HUHeiche US Surface Technology INC | Spartanburg | SC | Fabricated Metal Product Manufacturing332813 | — | ◇ UNVERIFIED |
| HIHoke INC | Spartanburg | SC | Fabricated Metal Product Manufacturing332919 | — | ◇ UNVERIFIED |
| HFHome Fabrics By Arcon LLC | Spartanburg | SC | Textile Mills313310 | — | ◇ UNVERIFIED |
| IUIna USA Corporation Plant Iv | Spartanburg | SC | Fabricated Metal Product Manufacturing332991 | — | ◇ UNVERIFIED |
| ITIntelicoat Technologies-closed | Spartanburg | SC | Plastics and Rubber Products Manufacturing326130 | — | ◇ UNVERIFIED |
| KAKing Asphalt Number 4 | Spartanburg | SC | Petroleum and Coal Products Manufacturing324121 | — | ◇ UNVERIFIED |
| LCLsc Communications Spartanburg | Spartanburg | SC | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| NCNemato Corporation | Spartanburg | SC | Plastics and Rubber Products Manufacturing326122 | — | ◇ UNVERIFIED |
| PMPepsi-cola Metropolitan Bottling | Spartanburg | SC | Beverage and Tobacco Product Manufacturing312111 | — | ◇ UNVERIFIED |
| PRPhoenix Racing INC | Spartanburg | SC | Transportation Equipment Manufacturing336999 | — | ◇ UNVERIFIED |
| PCPiedmont Concrete:spartanburg | Spartanburg | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| QPQuad Packaging INC | Spartanburg | SC | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| RBReeves Brothers INC Spartanburg Advanced | Spartanburg | SC | Textile Mills313210 | — | ◇ UNVERIFIED |
| SWSherwin Williams Spartanburg | Spartanburg | SC | Chemical Manufacturing325510 | — | ◇ UNVERIFIED |
| SSSpartanburg Stainless Products | Spartanburg | SC | Fabricated Metal Product Manufacturing332119 | — | ◇ UNVERIFIED |
| TPTegrant Property Holdings, LLC | Spartanburg | SC | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| TWThe Whitaker Company | Spartanburg | SC | Chemical Manufacturing325180 | — | ◇ UNVERIFIED |
| TCThomas Concrete of South Carolina Spartanburg Plt | Spartanburg | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| TCThomas Concrete of South Carolina Tissue Plant | Spartanburg | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| TITuscarora INC - Closed | Spartanburg | SC | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| WCWolverine Coatings CORP | Spartanburg | SC | Chemical Manufacturing325510 | — | ◇ UNVERIFIED |
