| PSPhotonis Scientific, Inc. | Sturbridge | MA | Computer and Electronic Product Manufacturing334419 | 20-99 | ◐ LIKELY ACTIVE |
| PFPolyvinyl Films INC. | Sutton | MA | Plastics and Rubber Products Manufacturing326111 | 100-499 | ◐ LIKELY ACTIVE |
| PSPrecast Specialties Corp | Abington | MA | Nonmetallic Mineral Product Manufacturing327390 | 20-99 | ◐ LIKELY ACTIVE |
Promounds LLC | Randolph | MA | Miscellaneous Manufacturing339920 | — | ◐ LIKELY ACTIVE |
| RHRadius Health, INC | Boston | MA | Chemical Manufacturing325412 | 100-499 | ◐ LIKELY ACTIVE |
| RBRentschler Biopharma Inc. | Milford | MA | Chemical Manufacturing325414 | 100-499 | ◐ LIKELY ACTIVE |
| RMRevolutionary Manufacturing Solutions, LLC | East Boston | MA | Fabricated Metal Product Manufacturing332710 | — | ◐ LIKELY ACTIVE |
| RIRevvity INC | Waltham | MA | Computer and Electronic Product Manufacturing334510 | 20-99 | ◐ LIKELY ACTIVE |
| RLRoofblok Limited | Gardner | MA | Nonmetallic Mineral Product Manufacturing327331 | 20-99 | ◐ LIKELY ACTIVE |
| RBRunning Brook Vineyard & Winery, INC. | North Dartmouth | MA | Beverage and Tobacco Product Manufacturing312130 | 1-19 | ◐ LIKELY ACTIVE |
Safehands Distribution Ne, LLC | Indian Orchard | MA | Chemical Manufacturing325612 | — | ◐ LIKELY ACTIVE |
| SFSaloom Furniture | Winchendon | MA | Furniture and Related Product Manufacturing337122 | 20-99 | ◐ LIKELY ACTIVE |
| SSSealcoat Supplier INC | Worcester | MA | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| SCSeminex Corporation | Danvers | MA | Computer and Electronic Product Manufacturing334413 | 1-19 | ◐ LIKELY ACTIVE |
| SPServier Pharmaceuticals LLC | Boston | MA | Chemical Manufacturing325412 | 100-499 | ◐ LIKELY ACTIVE |
Sherryi.llc | Danvers | MA | Miscellaneous Manufacturing339999 | — | ◐ LIKELY ACTIVE |
| SESolid Energy Systems LLC 35 Cabot | Woburn | MA | Electrical Equipment, Appliance & Component Manufacturing335910 | 20-99 | ◐ LIKELY ACTIVE |
| SPSpecialized Paper Converting | Gardner | MA | Paper Manufacturing322299 | 20-99 | ◐ LIKELY ACTIVE |
| SBSpindrift Beverage Co. | Newton | MA | Beverage and Tobacco Product Manufacturing312112 | 100-499 | ◐ LIKELY ACTIVE |
| SCSterilite Corporation - SHO | Townsend | MA | Plastics and Rubber Products Manufacturing326199 | 100-499 | ◐ LIKELY ACTIVE |
| SJSt Josephs Abbey | Spencer | MA | Food Manufacturing311421 | 1-19 | ◐ LIKELY ACTIVE |
| SISuns International LLC | Chelmsford | MA | Electrical Equipment, Appliance & Component Manufacturing335313 | — | ◐ LIKELY ACTIVE |
| SNSuperior Nut Co., Inc. | Cambridge | MA | Food Manufacturing311911 | 20-99 | ◐ LIKELY ACTIVE |
Surgical Specialties Corporation | Westwood | MA | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| TPTakeda Pharmaceuticals U.S.A., Inc. | Cambridge | MA | — | 500+ | ◐ LIKELY ACTIVE |
Tellbio, INC. | West Newbury | MA | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| TITeradyne, INC. | North Reading | MA | Computer and Electronic Product Manufacturing334515 | — | ◐ LIKELY ACTIVE |
| TATesco Associates INC | Tyngsborough | MA | Miscellaneous Manufacturing339113 | 20-99 | ◐ LIKELY ACTIVE |
| TBTraditional Breads | Lynn | MA | Food Manufacturing311812 | 20-99 | ◐ LIKELY ACTIVE |
| TPTransom Post OpCo, LLC dba Bose Professional | Hopkinton | MA | Computer and Electronic Product Manufacturing334310 | 100-499 | ◐ LIKELY ACTIVE |
| TITrivak Incorporated | Lowell | MA | Fabricated Metal Product Manufacturing332312 | 1-19 | ◐ LIKELY ACTIVE |
Trivedi Advanced Technologies LLC | Northborough | MA | Computer and Electronic Product Manufacturing334519 | — | ◐ LIKELY ACTIVE |
| TRTwin River Technologies | Quincy | MA | Chemical Manufacturing325199 | 100-499 | ◐ LIKELY ACTIVE |
| VVVata Verks INC | Arlington | MA | Computer and Electronic Product Manufacturing334514 | — | ◐ LIKELY ACTIVE |
| VIVerastem, INC. | Needham | MA | Chemical Manufacturing325412 | 20-99 | ◐ LIKELY ACTIVE |
| VQVerne Q Powell Flutes INC | Maynard | MA | Miscellaneous Manufacturing339930 | 20-99 | ◐ LIKELY ACTIVE |
Vizgen INC | Cambridge | MA | Computer and Electronic Product Manufacturing334516 | — | ◐ LIKELY ACTIVE |
| WTWaters Technologies Corporation | Milford | MA | Computer and Electronic Product Manufacturing334516 | 500+ | ◐ LIKELY ACTIVE |
Winchester Systems INC. | Littleton | MA | Computer and Electronic Product Manufacturing334112 | — | ◐ LIKELY ACTIVE |
| WGWyrmwood Gaming | Taunton | MA | Furniture and Related Product Manufacturing337122 | 20-99 | ◐ LIKELY ACTIVE |
| YTYokohama TWS - Wakefield | Wakefield | MA | Plastics and Rubber Products Manufacturing326211 | 20-99 | ◐ LIKELY ACTIVE |
Zero Asic CORP | Lexington | MA | Computer and Electronic Product Manufacturing334413 | — | ◐ LIKELY ACTIVE |
| AMAcorn Manufacturing | Mansfield | MA | Fabricated Metal Product Manufacturing332510 | 20-99 | ◐ LIKELY ACTIVE |
| AAgenus | Lexington | MA | Chemical Manufacturing325414 | 100-499 | ◐ LIKELY ACTIVE |
| AGA Group INC | Winchester | MA | Paper Manufacturing322299 | 20-99 | ◐ LIKELY ACTIVE |
| ALAhead LLC | New Bedford | MA | Apparel Manufacturing315990 | 100-499 | ◐ LIKELY ACTIVE |
| ACAlloy Castings CO INC | East Bridgewater | MA | Primary Metal Manufacturing331521 | 1-19 | ◐ LIKELY ACTIVE |
| AMA & M Associates Holdings LTD | Lakeville | MA | Electrical Equipment, Appliance & Component Manufacturing335999 | 1-19 | ◐ LIKELY ACTIVE |
| ASAutomatic Specialties, INC. | Marlborough | MA | Fabricated Metal Product Manufacturing332618 | 1-19 | ◐ LIKELY ACTIVE |
| ALAviva Labs, Inc. | Wilmington | MA | Chemical Manufacturing325411 | 1-19 | ◐ LIKELY ACTIVE |