| OPOrion Performance Compounds, INC. | Lugoff | SC | Chemical Manufacturing325211 | — | ◐ LIKELY ACTIVE |
| ODOshkosh Defense LLC | Spartanburg | SC | Transportation Equipment Manufacturing336110 | — | ◐ LIKELY ACTIVE |
| OTOstrem Tool Company, INC. | Lyman | SC | Machinery Manufacturing333514 | — | ◐ LIKELY ACTIVE |
| OCOwens Corning Non-woven LLC - Blythewood | Blythewood | SC | Textile Mills313230 | — | ◐ LIKELY ACTIVE |
| PCPalmetto Corporation Bishopville Plant | Bishopville | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| PCPalmetto Corporation Conway Plant | Conway | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| PCPalmetto Corporation of Conway - Orangeburg Plant | Bowman | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| PPPalmetto Paving Florence | Florence | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| PPPalmetto Paving Lugoff | Lugoff | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| PSPalmetto State Armory LLC | Columbia | SC | Fabricated Metal Product Manufacturing332111 | — | ◐ LIKELY ACTIVE |
| PAPanagakos Asphalt Paving Gray Court | Gray Court | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| PCPeddinghaus Corporation - PCSC | Andrews | SC | Machinery Manufacturing333517 | 20-99 | ◐ LIKELY ACTIVE |
| PFPerformance Friction CORP | Clover | SC | Machinery Manufacturing333999 | — | ◐ LIKELY ACTIVE |
| PPPerformance Pipe Startex Plant | Wellford | SC | Plastics and Rubber Products Manufacturing326122 | 20-99 | ◐ LIKELY ACTIVE |
| PAPharmaceutical Associates Incorporated | Greenville | SC | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| PMPhoto Marker Ii Incorporated | Spartanburg | SC | Paper Manufacturing322220 | — | ◐ LIKELY ACTIVE |
| PCPickens Construction INC | Anderson | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| PMPierce Machinery | Andrews | SC | Fabricated Metal Product Manufacturing332710 | 20-99 | ◐ LIKELY ACTIVE |
| PCPioneer Chemical | Greenville | SC | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| PSPolar Service Centers | Spartanburg | SC | Machinery Manufacturing333924 | — | ◐ LIKELY ACTIVE |
| PIPoly-med, INC | Piedmont | SC | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| PPPolymer Processing Inc | Rock Hill | SC | Chemical Manufacturing325211 | 20-99 | ◐ LIKELY ACTIVE |
| PCPort City Concrete- Harleyville | Harleyville | SC | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| PCPort City Concrete- Pace | North Charleston | SC | Nonmetallic Mineral Product Manufacturing327320 | 1-19 | ◐ LIKELY ACTIVE |
| PIPremier Industries INC | Anderson | SC | Plastics and Rubber Products Manufacturing326140 | — | ◐ LIKELY ACTIVE |
| PFPrestage Farms INC | Cassatt | SC | Food Manufacturing311119 | — | ◐ LIKELY ACTIVE |
| PPProtech Powder Coatings INC | Spartanburg | SC | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| PIProtego (usa) INC | Ladson | SC | Fabricated Metal Product Manufacturing332911 | 20-99 | ◐ LIKELY ACTIVE |
| QPQuikrete Proposed Storage Yard Site Improvements | Bowman | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| RCRe:build Cr, LLC | Rock Hill | SC | Chemical Manufacturing325211 | — | ◐ LIKELY ACTIVE |
| RCReeves Construction Company - Lakeside Asphalt Plant | Greenville | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| RCReeves Construction Company - North Columbia Asphalt Plant | Columbia | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| RBRobert Bosch LLC | Anderson | SC | Transportation Equipment Manufacturing336310 | 500+ | ◐ LIKELY ACTIVE |
| SASage Automotive Interiors Gayley Plant | Marietta | SC | Textile Mills313240 | — | ◐ LIKELY ACTIVE |
| SRSandy Run Roasting Plant | Gaston | SC | Food Manufacturing311920 | 100-499 | ◐ LIKELY ACTIVE |
| SRSantee Redi Mix | Moncks Corner | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| SCSatterfield Construction Company | Greenwood | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| SCSatterfield Construction Company - Clinton Asphalt Plant | Clinton | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| SCSatterfield Construction Company INC Eureka | Eureka | SC | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| SPSaybrook Plant | Inman | SC | Textile Mills313110 | 100-499 | ◐ LIKELY ACTIVE |
| SDSc Distributors INC | Cherokee Falls | SC | Textile Mills313210 | — | ◐ LIKELY ACTIVE |
| SGSchaeffler Group USA Inc. - Plant 1 | Cheraw | SC | Fabricated Metal Product Manufacturing332991 | 500+ | ◐ LIKELY ACTIVE |
| SASecondary Aluminum Target LLC | Moncks Corner | SC | Primary Metal Manufacturing331314 | — | ◐ LIKELY ACTIVE |
| SESew Eurodrive Incorporated | Lyman | SC | Machinery Manufacturing333612 | — | ◐ LIKELY ACTIVE |
| SESEW Eurodrive Lyman Assembly | Wellford | SC | Machinery Manufacturing333612 | 100-499 | ◐ LIKELY ACTIVE |
| SIShaw Industries Group Incorporated | Aiken | SC | Textile Product Mills314110 | — | ◐ LIKELY ACTIVE |
| SHSid Harvey Industries INC | Andrews | SC | Machinery Manufacturing333415 | — | ◐ LIKELY ACTIVE |
| SISiegwerk Ink Packaging | Boiling Springs | SC | Chemical Manufacturing325910 | — | ◐ LIKELY ACTIVE |
Signode Industrial Group-Latta | Latta | SC | Textile Product Mills314991 | 20-99 | ◐ LIKELY ACTIVE |
| SGSI Group | Orangeburg | SC | Chemical Manufacturing325199 | 100-499 | ◐ LIKELY ACTIVE |