| CCCarolina Concrete Company - Clinton | Clinton | SC | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| CICharles Ingram Lumber CO INC | Effingham | SC | Wood Product Manufacturing321113 | 100-499 | ◐ LIKELY ACTIVE |
| COConfluence Outdoor Incorporated | Greenville | SC | Transportation Equipment Manufacturing336612 | 100-499 | ◐ LIKELY ACTIVE |
| DADak Americas LLC | Moncks Corner | SC | Chemical Manufacturing325211 | — | ◐ LIKELY ACTIVE |
| DCDawkins Concrete Products INC | Hartsville | SC | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
| DADenkai America INC | Camden | SC | Fabricated Metal Product Manufacturing332812 | — | ◐ LIKELY ACTIVE |
| EIEeea INC | Mauldin | SC | Fabricated Metal Product Manufacturing332813 | 20-99 | ◐ LIKELY ACTIVE |
| FBFalcon Boats LLC | Newberry | SC | Transportation Equipment Manufacturing336612 | 20-99 | ◐ LIKELY ACTIVE |
| FBFreeman Boatworks LLC | Moncks Corner | SC | Transportation Equipment Manufacturing336612 | 100-499 | ◐ LIKELY ACTIVE |
| FAFukoku America, INC | Laurens | SC | Plastics and Rubber Products Manufacturing326291 | 100-499 | ◐ LIKELY ACTIVE |
| IKInternational Knife & Saw Incorporated | Florence | SC | Fabricated Metal Product Manufacturing332710 | 20-99 | ◐ LIKELY ACTIVE |
| JMJb Martin Company Incorporated | Leesville | SC | Textile Mills313210 | 100-499 | ◐ LIKELY ACTIVE |
| KIKoppers Industries Incorporated | Florence | SC | Wood Product Manufacturing321114 | — | ◐ LIKELY ACTIVE |
| LTLift Technologies INC | Westminster | SC | Machinery Manufacturing333924 | 100-499 | ◐ LIKELY ACTIVE |
| MMMk Metalfoils USA INC | Duncan | SC | Primary Metal Manufacturing331221 | 1-19 | ◐ LIKELY ACTIVE |
| MTMorrison Textiles Machinery CO | Ft Lawn | SC | Machinery Manufacturing333248 | 1-19 | ◐ LIKELY ACTIVE |
| OCOmega Chemicals INC | Cowpens | SC | Chemical Manufacturing325110 | 1-19 | ◐ LIKELY ACTIVE |
| PIPalmetto Imaging Technology | Winnsboro | SC | Chemical Manufacturing325510 | 1-19 | ◐ LIKELY ACTIVE |
| PFPatterson Fan - Office Addition | Blythewood | SC | Machinery Manufacturing333411 | 20-99 | ◐ LIKELY ACTIVE |
| RSRed Seal Measurement | Greenwood | SC | Computer and Electronic Product Manufacturing334514 | 20-99 | ◐ LIKELY ACTIVE |
| RTRoll Technology Corporation | Greenville | SC | Fabricated Metal Product Manufacturing332813 | 20-99 | ◐ LIKELY ACTIVE |
| SPSantee Print Works | Sumter | SC | Textile Mills313310 | 100-499 | ◐ LIKELY ACTIVE |
| SBSportsman Boat Manufacturing INC | Summerville | SC | Transportation Equipment Manufacturing336612 | 100-499 | ◐ LIKELY ACTIVE |
| SIStoll Industries, INC. | Abbeville | SC | Fabricated Metal Product Manufacturing332999 | 20-99 | ◐ LIKELY ACTIVE |
| SCSumter Coatings INC | Sumter | SC | Chemical Manufacturing325510 | 20-99 | ◐ LIKELY ACTIVE |
| SCSunbelt Corporation | Rock Hill | SC | Chemical Manufacturing325110 | 1-19 | ◐ LIKELY ACTIVE |
| TUTrebol USA LLC | Andrews | SC | Nonmetallic Mineral Product Manufacturing327992 | 20-99 | ◐ LIKELY ACTIVE |
| TBT&s Brass & Bronze Works INC | Travelers Rest | SC | Fabricated Metal Product Manufacturing332913 | 100-499 | ◐ LIKELY ACTIVE |
| VLVetroresina LLC | Greenville | SC | Plastics and Rubber Products Manufacturing326130 | 20-99 | ◐ LIKELY ACTIVE |
| 6C69383 - Colgate-palmolive Company | Hodges | SC | Chemical Manufacturing325611 | 100-499 | ◐ LIKELY ACTIVE |
| 6K69802 - Kiswire, INC. | Newberry | SC | Primary Metal Manufacturing331111 | 100-499 | ◐ LIKELY ACTIVE |
| 6C69954 - Constantia Blythewood LLC | Blythewood | SC | Printing and Related Support Activities323120 | 100-499 | ◐ LIKELY ACTIVE |
72178 - Continental Tire the Americas LLC | Sumter | SC | Plastics and Rubber Products Manufacturing326211 | 500+ | ◐ LIKELY ACTIVE |
| 7B72374 - Bmw Manufacturing CO LLC | Greer | SC | Transportation Equipment Manufacturing336110 | 500+ | ◐ LIKELY ACTIVE |
| 7G72431 - Guardian Industries LLC | Richburg | SC | Nonmetallic Mineral Product Manufacturing327211 | 100-499 | ◐ LIKELY ACTIVE |
| AIAci Industries, LLC | Laurens | SC | Nonmetallic Mineral Product Manufacturing327120 | 20-99 | ◐ LIKELY ACTIVE |
| ASAckerson Stevens Incorporated | Ware Shoals | SC | Wood Product Manufacturing321912 | 20-99 | ◐ LIKELY ACTIVE |
| ASAdvanta Southeast LLC | Manning | SC | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
| ATAfl Telecommunications 110 Hidden Lake Facility | Duncan | SC | Electrical Equipment, Appliance & Component Manufacturing335932 | — | ◐ LIKELY ACTIVE |
| AAAgru America INC | Georgetown | SC | Plastics and Rubber Products Manufacturing326113 | 100-499 | ◐ LIKELY ACTIVE |
| ANAkzo Nobel Coatings INC | Lancaster | SC | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| AAAllied Air Enterprises Incorporated | Orangeburg | SC | Machinery Manufacturing333415 | 500+ | ◐ LIKELY ACTIVE |
| AOAlumax of South Carolina INC | Goose Creek | SC | Primary Metal Manufacturing331312 | — | ◐ LIKELY ACTIVE |
| AOAmalie Oil Company (former Delfin Group Usa, Llc) | N Charleston | SC | Petroleum and Coal Products Manufacturing324191 | — | ◐ LIKELY ACTIVE |
| ASAmazon.com Services LLC Cae3 | West Columbia | SC | Printing and Related Support Activities323117 | 100-499 | ◐ LIKELY ACTIVE |
American Air & Water INC | Hilton Head Island | SC | Electrical Equipment, Appliance & Component Manufacturing335139 | 1-19 | ◐ LIKELY ACTIVE |
| ARAmsted Rail | Fountain Inn | SC | Transportation Equipment Manufacturing336510 | 20-99 | ◐ LIKELY ACTIVE |
| AHAnderson Hardwood Floors | Enoree | SC | Wood Product Manufacturing321211 | — | ◐ LIKELY ACTIVE |
| AOA O Smith Water Products Company | Mcbee | SC | Fabricated Metal Product Manufacturing332410 | — | ◐ LIKELY ACTIVE |
| ASApexical Spartanburg | Spartanburg | SC | Chemical Manufacturing325998 | 20-99 | ◐ LIKELY ACTIVE |