| CICabot Inkjet Colorants | Haverhill | MA | Chemical Manufacturing325910 | — | ◐ LIKELY ACTIVE |
| CCCamger Coatings Systems, Inc. | Norfolk | MA | Chemical Manufacturing325510 | 20-99 | ◐ LIKELY ACTIVE |
| CMCannatech Medicinals Innovation | Assonet | MA | Chemical Manufacturing325411 | — | ◐ LIKELY ACTIVE |
| CDCanton Distributors | Canton | MA | Food Manufacturing311812 | 100-499 | ◐ LIKELY ACTIVE |
| CCCape Cod Winery INC | East Falmouth | MA | Beverage and Tobacco Product Manufacturing312130 | 1-19 | ◐ LIKELY ACTIVE |
| CICastle Island Brewing Co. | Boston | MA | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| CMCatalent Massachusetts LLC | Chelsea | MA | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
Cenveo Worldwide Ltd. Chicopee | Chicopee | MA | Paper Manufacturing322230 | 100-499 | ◐ LIKELY ACTIVE |
| CCCertainteed Corporation | Norwood | MA | Petroleum and Coal Products Manufacturing324122 | 100-499 | ◐ LIKELY ACTIVE |
| CSCgit Systems INC | Medway | MA | Electrical Equipment, Appliance & Component Manufacturing335999 | — | ◐ LIKELY ACTIVE |
| CLCitra Labs (zimmer-biomet Co.) | Braintree | MA | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| CMCogentix Medical INC | Westborough | MA | Miscellaneous Manufacturing339112 | — | ◐ LIKELY ACTIVE |
| CICometeer INC | Gloucester | MA | Food Manufacturing311920 | 20-99 | ◐ LIKELY ACTIVE |
| CNCommunity Newspaper Company | Framingham | MA | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| CICoorstek, INC. | Worcester | MA | Nonmetallic Mineral Product Manufacturing327110 | — | ◐ LIKELY ACTIVE |
| CDCourtsmart Digital Systems, INC. | North Chelmsford | MA | Computer and Electronic Product Manufacturing334310 | 20-99 | ◐ LIKELY ACTIVE |
| CRCovanta Resource Recovery Facility | Haverhill | MA | Machinery Manufacturing333999 | — | ◐ LIKELY ACTIVE |
| CBCpi Beverly Microwave Division | Beverly | MA | Computer and Electronic Product Manufacturing334220 | — | ◐ LIKELY ACTIVE |
| CICraft, Inc. | South Attleboro | MA | Fabricated Metal Product Manufacturing332116 | 20-99 | ◐ LIKELY ACTIVE |
| CECreative Extrusion and Technologies Incorporated | Brockton | MA | Plastics and Rubber Products Manufacturing326121 | 1-19 | ◐ LIKELY ACTIVE |
| CLCresco Labs | Fall River | MA | Chemical Manufacturing325413 | — | ◐ LIKELY ACTIVE |
| CICristek Interconnects, LLC | North Billerica | MA | Computer and Electronic Product Manufacturing334419 | — | ◐ LIKELY ACTIVE |
| CPCrocetti-oakdale Packing, INC | Brockton | MA | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| CMCuria Massachusetts INC | Burlington | MA | Chemical Manufacturing325412 | 20-99 | ◐ LIKELY ACTIVE |
| CMCustom Mold & Machine, Inc. | Norton | MA | Machinery Manufacturing333511 | 1-19 | ◐ LIKELY ACTIVE |
| DADba Accurate Plastics | East Falmouth | MA | Paper Manufacturing322222 | — | ◐ LIKELY ACTIVE |
| DGDeacon Giles Distillery | Salem | MA | Beverage and Tobacco Product Manufacturing312140 | — | ◐ LIKELY ACTIVE |
| DIDeAngelis Iron Work Inc. | S. Easton | MA | Fabricated Metal Product Manufacturing332323 | 20-99 | ◐ LIKELY ACTIVE |
| DPDeano's Pastacia, Inc. | Somerville | MA | Food Manufacturing311612 | 20-99 | ◐ LIKELY ACTIVE |
| DSDelta Sand and Gravel | Sunderland | MA | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| DDexter-russell | Sturbridge | MA | Fabricated Metal Product Manufacturing332215 | — | ◐ LIKELY ACTIVE |
| DIDfa Ice Cream - Wilbraham Ma | Wilbraham | MA | Food Manufacturing311520 | 100-499 | ◐ LIKELY ACTIVE |
| DGD. G. Marshall Associates, INC | Webster | MA | Transportation Equipment Manufacturing336211 | 1-19 | ◐ LIKELY ACTIVE |
| DSDielectric Sciences, INC. | Chelmsford | MA | Electrical Equipment, Appliance & Component Manufacturing335999 | — | ◐ LIKELY ACTIVE |
| DMDi-mo Manufacturing, INC. | Middleboro | MA | Plastics and Rubber Products Manufacturing326199 | 1-19 | ◐ LIKELY ACTIVE |
| DMDutch Maid Bakery | Dorchester | MA | Food Manufacturing311813 | 100-499 | ◐ LIKELY ACTIVE |
| ECEarthsafe Chemical Alternatives | Braintree | MA | Chemical Manufacturing325188 | — | ◐ LIKELY ACTIVE |
| EBEastman Brass Instruments, LLC | Holliston | MA | Miscellaneous Manufacturing339992 | 20-99 | ◐ LIKELY ACTIVE |
| EEasypak | Leominster | MA | Plastics and Rubber Products Manufacturing326121 | 100-499 | ◐ LIKELY ACTIVE |
| EHE H Metalcraft Co, INC. | West Bridgewater | MA | Fabricated Metal Product Manufacturing332710 | 1-19 | ◐ LIKELY ACTIVE |
| EBE.L. Blood & Son, Inc. | West Groton | MA | Food Manufacturing311611 | 20-99 | ◐ LIKELY ACTIVE |
| EHEmerson Hospital | Concord | MA | Machinery Manufacturing333921 | — | ◐ LIKELY ACTIVE |
| EIErgomet INC | Ward Hill | MA | Fabricated Metal Product Manufacturing332322 | 20-99 | ◐ LIKELY ACTIVE |
| EEEvoloh East | Lowell | MA | Electrical Equipment, Appliance & Component Manufacturing335999 | 20-99 | ◐ LIKELY ACTIVE |
| EEyePoint | Watertown | MA | Chemical Manufacturing325412 | 100-499 | ◐ LIKELY ACTIVE |
| FSFagron Sterile Services Boston | Canton | MA | Chemical Manufacturing325412 | 100-499 | ◐ LIKELY ACTIVE |
| FMFp Mcnamara Rubbish Removal INC | Springfield | MA | Fabricated Metal Product Manufacturing332111 | — | ◐ LIKELY ACTIVE |
| FIFresh Ideas, INC. | Charlestown | MA | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| FHFujifilm Healthcare Americas Corporation Lexington | Lexington | MA | Computer and Electronic Product Manufacturing334510 | 500+ | ◐ LIKELY ACTIVE |
| GFGarlock Flexibles | Gardner | MA | Printing and Related Support Activities323111 | 20-99 | ◐ LIKELY ACTIVE |