| MIMalanden INC | Sioux Falls | SD | Food Manufacturing311520 | — | ◇ UNVERIFIED |
| MWMcintosh Watauga Equity | Mcintosh | SD | Food Manufacturing311119 | — | ◇ UNVERIFIED |
| MBMeyer's Bakery Co | Sioux Falls | SD | Food Manufacturing311812 | — | ◇ UNVERIFIED |
| MUMidcom Unit Midtex Division (former Location) | Watertown | SD | Computer and Electronic Product Manufacturing334419 | — | ◇ UNVERIFIED |
| MSMidwest Stone Manufacturing Company | Tea | SD | Nonmetallic Mineral Product Manufacturing327991 | — | ◇ UNVERIFIED |
| MKMindless Kreations LLC | Whitewood | SD | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| MGMNY Group, LLC | Madison | SD | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| MFMolded Fiber Glass /south Dakota | Aberdeen | SD | Machinery Manufacturing333611 | — | ◇ UNVERIFIED |
| MWMountain West, LLC | Piedmont | SD | Wood Product Manufacturing321999 | — | ◇ UNVERIFIED |
| MRM & R 281 Locker LLC | Stickney | SD | Food Manufacturing311612 | — | ◇ UNVERIFIED |
| MPMueller Pallets, LLC | Sioux Falls | SD | Wood Product Manufacturing321920 | — | ◇ UNVERIFIED |
| MTMuskrat Technologies | Buffalo | SD | Miscellaneous Manufacturing339999 | — | ◇ UNVERIFIED |
| MMMyer-hall Machine Works INC | Canton | SD | Machinery Manufacturing333248 | — | ◇ UNVERIFIED |
| NSNatural Stone Manufacturers Inc | Lennox | SD | Nonmetallic Mineral Product Manufacturing327991 | — | ◇ UNVERIFIED |
| NSNatural Stone Manufacturers, Inc. | Lennox | SD | Nonmetallic Mineral Product Manufacturing327991 | — | ◇ UNVERIFIED |
| NSNuEra Steel LLC | Viborg | SD | Fabricated Metal Product Manufacturing332312 | — | ◇ UNVERIFIED |
| PBPark Bench Management LLC | Black Hawk | SD | Printing and Related Support Activities323113 | — | ◇ UNVERIFIED |
| PTPermian Tank & Manufacturing INC Belle Fourche Plant | Belle Fourche | SD | Fabricated Metal Product Manufacturing332420 | — | ◇ UNVERIFIED |
| PIPrairie Industries, LLC | Vale | SD | Fabricated Metal Product Manufacturing332999 | — | ◇ UNVERIFIED |
| PSPrairie Stone LLC | New Effington | SD | Nonmetallic Mineral Product Manufacturing327991 | — | ◇ UNVERIFIED |
| RCRapid City Apb | Rapid City | SD | Chemical Manufacturing325998 | — | ◇ UNVERIFIED |
| RPRapid Packaging Company, INC. | Brookings | SD | Paper Manufacturing322211 | — | ◇ UNVERIFIED |
| RMRay Manufacturing LLC | Watertown | SD | Fabricated Metal Product Manufacturing332710 | — | ◇ UNVERIFIED |
| RBReaves Building Systems | Sioux Falls | SD | Wood Product Manufacturing321214 | — | ◇ UNVERIFIED |
| RMRecycled Materials Inc | Lennox | SD | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| RLRizco, LLC | Rapid City | SD | Electrical Equipment, Appliance & Component Manufacturing335311 | — | ◇ UNVERIFIED |
| RMRoto Mold, L.L.C. | Tea | SD | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| SBSab Biotherapeutics | Sioux Falls | SD | Chemical Manufacturing325414 | — | ◇ UNVERIFIED |
| SRSalem Ready Mix, LLC | Salem | SD | Nonmetallic Mineral Product Manufacturing327320 | — | ◇ UNVERIFIED |
| SESamson Exhaust | Sturgis | SD | Fabricated Metal Product Manufacturing332999 | — | ◇ UNVERIFIED |
| SPSCC Properties, LLC | Sioux Falls | SD | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| SESDR Enterprises Inc | Revillo | SD | Plastics and Rubber Products Manufacturing326199 | — | ◇ UNVERIFIED |
| SDSexauer Discount Farm Services, INC. | Brookings | SD | Food Manufacturing311119 | — | ◇ UNVERIFIED |
| SMSfkb Millwork | Sioux Falls | SD | Furniture and Related Product Manufacturing337110 | — | ◇ UNVERIFIED |
| SLSignature Lettering, LLC | Sioux Falls | SD | Printing and Related Support Activities323111 | — | ◇ UNVERIFIED |
| SFSmack Foods, INC. | Hurley | SD | Food Manufacturing311999 | — | ◇ UNVERIFIED |
| SSSmudge Studios LLC | Sioux Falls | SD | Nonmetallic Mineral Product Manufacturing327110 | — | ◇ UNVERIFIED |
| SSSodak Soda LLC | Sioux Falls | SD | Beverage and Tobacco Product Manufacturing312111 | — | ◇ UNVERIFIED |
| SSState Steel of South Dakota, INC. | Sioux Falls | SD | Primary Metal Manufacturing331110 | — | ◇ UNVERIFIED |
| SBSturgis Brewing Company | Sturgis | SD | Beverage and Tobacco Product Manufacturing312120 | — | ◇ UNVERIFIED |
| SMSturgis Meats LLC | Rapid City | SD | Food Manufacturing311611 | — | ◇ UNVERIFIED |
| SMSturgis Meats LLC | Custer | SD | Food Manufacturing311611 | — | ◇ UNVERIFIED |
| SDSunrise Dairy, LLC | Clear Lake | SD | Food Manufacturing311511 | — | ◇ UNVERIFIED |
| TAT and K Hunting Gear LLC | Rapid City | SD | Apparel Manufacturing315990 | — | ◇ UNVERIFIED |
| TCTerex Corporation | Canton | SD | Machinery Manufacturing333120 | — | ◇ UNVERIFIED |
| TBThe Breaks Coffee Roasting Co | Sioux Falls | SD | Food Manufacturing311920 | — | ◇ UNVERIFIED |
 Thermo Bond Buildings, INC. | Elk Point | SD | Wood Product Manufacturing321992 | — | ◇ UNVERIFIED |
| TTTotally Tubular Mfg., INC. | Aberdeen | SD | Fabricated Metal Product Manufacturing332311 | — | ◇ UNVERIFIED |
 Truenorth Steel - Huron | Huron | SD | Fabricated Metal Product Manufacturing332312 | — | ◇ UNVERIFIED |
| TCTwin City Fan Companies, LTD | Elkton | SD | Machinery Manufacturing333413 | — | ◇ UNVERIFIED |
