| JNJTEKT North America | Blythewood | SC | Fabricated Metal Product Manufacturing332991 | 500+ | ◐ LIKELY ACTIVE |
| KEKemet Electronics Corporation | Simpsonville | SC | Computer and Electronic Product Manufacturing334414 | 100-499 | ◐ LIKELY ACTIVE |
| KWKey West Boats Expansion | Ridgeville | SC | Transportation Equipment Manufacturing336611 | — | ◐ LIKELY ACTIVE |
| KWKey West Boats :summerville | Summerville | SC | Transportation Equipment Manufacturing336612 | — | ◐ LIKELY ACTIVE |
| KPKimberly-clark Palmetto | Beech Island | SC | Paper Manufacturing322120 | — | ◐ LIKELY ACTIVE |
| KRKnight Redi-mix Inc., - Plant 5 | North Charleston | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| LPLeisure Pools and Spas Manufacturing North America INC | Marion | SC | Plastics and Rubber Products Manufacturing326199 | — | ◐ LIKELY ACTIVE |
| LCLindau Chemicals, INC. | Columbia | SC | Chemical Manufacturing325194 | 20-99 | ◐ LIKELY ACTIVE |
| MSMagna Seating South Carolina | Moore | SC | Transportation Equipment Manufacturing336360 | 500+ | ◐ LIKELY ACTIVE |
| MPMarlboro Paper Mill | Bennettsville | SC | Paper Manufacturing322110 | — | ◐ LIKELY ACTIVE |
| MPMars Pet Care US INC Columbia | Columbia | SC | Food Manufacturing311111 | — | ◐ LIKELY ACTIVE |
Mclaughlin Body Company INC | Anderson | SC | Fabricated Metal Product Manufacturing332812 | 20-99 | ◐ LIKELY ACTIVE |
| MLMenardi LLC | Trenton | SC | Textile Product Mills314999 | 20-99 | ◐ LIKELY ACTIVE |
| MNMichelin N America Inc/us2 | Pendleton | SC | Plastics and Rubber Products Manufacturing326211 | — | ◐ LIKELY ACTIVE |
| MNMichelin North America INC - Spartanburg Facility (us3) | Spartanburg | SC | Plastics and Rubber Products Manufacturing326211 | — | ◐ LIKELY ACTIVE |
| MNMichelin North America INC Us10 | Anderson | SC | Plastics and Rubber Products Manufacturing326211 | — | ◐ LIKELY ACTIVE |
| MTMichelin Tweel Technology | Piedmont | SC | Plastics and Rubber Products Manufacturing326211 | 20-99 | ◐ LIKELY ACTIVE |
| MCMiliken & Company Enterprise Plant | Marietta | SC | Textile Mills313210 | 100-499 | ◐ LIKELY ACTIVE |
| MCMilliken Chemical - Dewey Plant | Inman | SC | Chemical Manufacturing325110 | — | ◐ LIKELY ACTIVE |
| MSMita South Carolina Incorporated | Fountain Inn | SC | Computer and Electronic Product Manufacturing334416 | — | ◐ LIKELY ACTIVE |
| MCMitsubishi Chemical America, Performance Polymers | Greer | SC | Chemical Manufacturing325211 | 20-99 | ◐ LIKELY ACTIVE |
| NSNephron Sc, LLC | West Columbia | SC | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| NHNexans High Voltage USA INC | Goose Creek | SC | Electrical Equipment, Appliance & Component Manufacturing335929 | 100-499 | ◐ LIKELY ACTIVE |
| NUNicca USA INC | Fountain Inn | SC | Chemical Manufacturing325199 | 20-99 | ◐ LIKELY ACTIVE |
| NMNova Molecular Sumter LLC | Sumter | SC | Chemical Manufacturing325199 | 20-99 | ◐ LIKELY ACTIVE |
| NCNucor CORP - Darlington Plant | Darlington | SC | Nonmetallic Mineral Product Manufacturing327320 | — | ◐ LIKELY ACTIVE |
| OBOldcastle Building Envelope | Rock Hill | SC | Nonmetallic Mineral Product Manufacturing327215 | 100-499 | ◐ LIKELY ACTIVE |
| OLOldcastle Lawn & Garden | Gaffney | SC | Wood Product Manufacturing321999 | — | ◐ LIKELY ACTIVE |
| OROrangeburg Redi Mix Concrete INC | Orangeburg | SC | Nonmetallic Mineral Product Manufacturing327320 | 20-99 | ◐ LIKELY ACTIVE |
Organic Dyes and Pigments | Union | SC | Chemical Manufacturing325130 | 1-19 | ◐ LIKELY ACTIVE |
| OCOwens Corning Vetrotex LLC - Anderson Sc | Anderson | SC | Nonmetallic Mineral Product Manufacturing327212 | — | ◐ LIKELY ACTIVE |
| PBPalmetto Brick | Wallace | SC | Nonmetallic Mineral Product Manufacturing327120 | — | ◐ LIKELY ACTIVE |
| PUPierburg US LLC | Fountain Inn | SC | Fabricated Metal Product Manufacturing332116 | 100-499 | ◐ LIKELY ACTIVE |
| PIPoly-med INC | Anderson | SC | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| QCQuikrete Construction Materials, LLC - Harleyville Cement Plant | Harleyville | SC | Nonmetallic Mineral Product Manufacturing327310 | — | ◐ LIKELY ACTIVE |
Rbc Aerostructures LLC | Westminster | SC | Transportation Equipment Manufacturing336411 | — | ◐ LIKELY ACTIVE |
| RBRexam Beverage Can Company | Bishopville | SC | Fabricated Metal Product Manufacturing332431 | — | ◐ LIKELY ACTIVE |
| RIRhodia INC. - Charleston, Sc Plant | Charleston | SC | Chemical Manufacturing325110 | — | ◐ LIKELY ACTIVE |
| RORmax Operating LLC | Greer | SC | Plastics and Rubber Products Manufacturing326121 | — | ◐ LIKELY ACTIVE |
| RFRmf Facility Piedmont | Piedmont | SC | Fabricated Metal Product Manufacturing332813 | — | ◐ LIKELY ACTIVE |
| RBRobert Bosch LLC | Anderson | SC | Computer and Electronic Product Manufacturing334515 | 500+ | ◐ LIKELY ACTIVE |
| RMRoy Metal Finishing RMF2 | Greenville | SC | Fabricated Metal Product Manufacturing332813 | 1-19 | ◐ LIKELY ACTIVE |
| SMSantolubes Manufacturing LLC | Spartanburg | SC | Chemical Manufacturing325110 | 20-99 | ◐ LIKELY ACTIVE |
| SGSchaeffler Group USA INC - Plant I I | Cheraw | SC | Fabricated Metal Product Manufacturing332991 | 100-499 | ◐ LIKELY ACTIVE |
| SESchneider Electric | Seneca | SC | Electrical Equipment, Appliance & Component Manufacturing335314 | 500+ | ◐ LIKELY ACTIVE |
| SBScout Boats | Summerville | SC | Transportation Equipment Manufacturing336612 | — | ◐ LIKELY ACTIVE |
| SPSc Pet Food Solutions, LLC | Ward | SC | Food Manufacturing311111 | 100-499 | ◐ LIKELY ACTIVE |
| SIShaw Industries Group INC Plant 8s | Columbia | SC | Chemical Manufacturing325211 | — | ◐ LIKELY ACTIVE |
| SCSignatures Company, LLC | Mauldin | SC | Textile Product Mills314999 | — | ◐ LIKELY ACTIVE |
| SJSmi Joist:cayce | Cayce | SC | Fabricated Metal Product Manufacturing332312 | — | ◐ LIKELY ACTIVE |