| RIReaxis INC | Mc Donald | PA | Chemical Manufacturing325130 | 20-99 | ◐ LIKELY ACTIVE |
| RIRegal Industrial Corporation | Donora | PA | Fabricated Metal Product Manufacturing332312 | 100-499 | ◐ LIKELY ACTIVE |
| RLReichdrill LLC | Philipsburg | PA | Machinery Manufacturing333120 | 20-99 | ◐ LIKELY ACTIVE |
| RPReilly Plating CO INC | Nanticoke | PA | Fabricated Metal Product Manufacturing332813 | 20-99 | ◐ LIKELY ACTIVE |
| RSReynolds Services INC | Greenville | PA | Primary Metal Manufacturing331221 | 100-499 | ◐ LIKELY ACTIVE |
| RMRitchey Metals CO Inc/hendersonville Plt | Canonsburg | PA | Primary Metal Manufacturing331314 | 100-499 | ◐ LIKELY ACTIVE |
| RMRobertson Manufacturing INC | West Grove | PA | Textile Product Mills314912 | 20-99 | ◐ LIKELY ACTIVE |
| RProse plastic USA LLLP | Coal Center | PA | Plastics and Rubber Products Manufacturing326112 | 20-99 | ◐ LIKELY ACTIVE |
| RRR & R Wood Products INC | Mainland | PA | Wood Product Manufacturing321920 | 1-19 | ◐ LIKELY ACTIVE |
| RMRTI Machine Inc. | Polk | PA | Fabricated Metal Product Manufacturing332710 | 20-99 | ◐ LIKELY ACTIVE |
| STSalem Tube Mfg | Greenville | PA | Primary Metal Manufacturing331110 | 100-499 | ◐ LIKELY ACTIVE |
| SCScranton Craftsmen Incorporated | Throop | PA | Nonmetallic Mineral Product Manufacturing327390 | 20-99 | ◐ LIKELY ACTIVE |
| SMSeaway Mfg CORP | Erie | PA | Wood Product Manufacturing321911 | 20-99 | ◐ LIKELY ACTIVE |
| SEShank's Extracts, LLC D/b/a Universal Ingredients-shank's | Lancaster | PA | Food Manufacturing311920 | 100-499 | ◐ LIKELY ACTIVE |
| SCSharon Coating | Sharon | PA | Fabricated Metal Product Manufacturing332322 | 100-499 | ◐ LIKELY ACTIVE |
| SPSharretts Plating CO INC | Emigsville | PA | Fabricated Metal Product Manufacturing332813 | 20-99 | ◐ LIKELY ACTIVE |
| SCSheffield Container Corporation | Sheffield | PA | Wood Product Manufacturing321920 | 20-99 | ◐ LIKELY ACTIVE |
| SASimona America INC. | Archbald | PA | Plastics and Rubber Products Manufacturing326113 | 100-499 | ◐ LIKELY ACTIVE |
| SISintergy, Inc, | Reynoldsville | PA | Fabricated Metal Product Manufacturing332117 | 20-99 | ◐ LIKELY ACTIVE |
| SLSintermet LLC | Kittanning | PA | Fabricated Metal Product Manufacturing332117 | 20-99 | ◐ LIKELY ACTIVE |
| SRSpecialty Ring Products INC | Bensalem | PA | Fabricated Metal Product Manufacturing332111 | 20-99 | ◐ LIKELY ACTIVE |
| SCSpeer Carbon CO | Saint Marys | PA | Electrical Equipment, Appliance & Component Manufacturing335991 | 1-19 | ◐ LIKELY ACTIVE |
Spring Health Products, INC. | Norristown | PA | Miscellaneous Manufacturing339114 | — | ◐ LIKELY ACTIVE |
| SHStandard Horse Nail Corporation | New Brighton | PA | Fabricated Metal Product Manufacturing332510 | 20-99 | ◐ LIKELY ACTIVE |
| SIStandard Iron Works | Scranton | PA | Fabricated Metal Product Manufacturing332312 | 20-99 | ◐ LIKELY ACTIVE |
State of the Art, INC. | State College | PA | Computer and Electronic Product Manufacturing334415 | — | ◐ LIKELY ACTIVE |
| SGStoelzle Glass USA Inc/monaca Plt | Monaca | PA | Nonmetallic Mineral Product Manufacturing327212 | 100-499 | ◐ LIKELY ACTIVE |
| SPSt Prod LLC Dba Wieland Small Tube Prod/altoona | Duncansville | PA | Primary Metal Manufacturing331318 | 100-499 | ◐ LIKELY ACTIVE |
Strube INC | Marietta | PA | Machinery Manufacturing333612 | 1-19 | ◐ LIKELY ACTIVE |
| SLStryten Lampeter LLC | Lancaster | PA | Plastics and Rubber Products Manufacturing326199 | 100-499 | ◐ LIKELY ACTIVE |
| STSummit Trailers LLC | Schuylkill Haven | PA | Transportation Equipment Manufacturing336212 | 20-99 | ◐ LIKELY ACTIVE |
| SQSuperior Quartz Products INC | Bethlehem | PA | Electrical Equipment, Appliance & Component Manufacturing335139 | 20-99 | ◐ LIKELY ACTIVE |
| SWSuperior Woodcraft/doylestown Plt | Doylestown | PA | Furniture and Related Product Manufacturing337110 | 20-99 | ◐ LIKELY ACTIVE |
| TTTeam Ten Tyrone Mill | Tyrone | PA | Paper Manufacturing322120 | 100-499 | ◐ LIKELY ACTIVE |
| TCTech Cast LLC | Myerstown | PA | Primary Metal Manufacturing331512 | 100-499 | ◐ LIKELY ACTIVE |
| TPTech Precision Sftf | Hadley | PA | Fabricated Metal Product Manufacturing332999 | 1-19 | ◐ LIKELY ACTIVE |
| TCTe Connectivity Bldg 158 | Manheim | PA | Computer and Electronic Product Manufacturing334417 | — | ◐ LIKELY ACTIVE |
| TWThe Warrell Corporation | Camp Hill | PA | Food Manufacturing311340 | 100-499 | ◐ LIKELY ACTIVE |
| TSTooling Specialists, INC. | Latrobe | PA | Fabricated Metal Product Manufacturing332710 | 20-99 | ◐ LIKELY ACTIVE |
| TITrafcon Industries, Inc. | Mechanicsburg | PA | Miscellaneous Manufacturing339950 | 20-99 | ◐ LIKELY ACTIVE |
| TKTri Kris CO INC | Lansdale | PA | Fabricated Metal Product Manufacturing332710 | 20-99 | ◐ LIKELY ACTIVE |
Tsitouch, INC | Uniontown | PA | Computer and Electronic Product Manufacturing334118 | 20-99 | ◐ LIKELY ACTIVE |
| THTurkey Hill | Conestoga | PA | Food Manufacturing311511 | 500+ | ◐ LIKELY ACTIVE |
| UPUltra Precision | Freeport | PA | Machinery Manufacturing333514 | 20-99 | ◐ LIKELY ACTIVE |
| UEUnion Elec Steel Corp/greengarden Ave | Erie | PA | Primary Metal Manufacturing331110 | 1-19 | ◐ LIKELY ACTIVE |
| UGUnited Gilsonite Labs | Dunmore | PA | Chemical Manufacturing325510 | 20-99 | ◐ LIKELY ACTIVE |
| UPUnited Plate Glass Company (Butler) | Butler | PA | Nonmetallic Mineral Product Manufacturing327215 | 100-499 | ◐ LIKELY ACTIVE |
| UCUniversal Concrete Prod Corp/stowe | Stowe | PA | Nonmetallic Mineral Product Manufacturing327320 | 100-499 | ◐ LIKELY ACTIVE |
Universal Printing Company, LLC | Dunmore | PA | Printing and Related Support Activities323110 | 100-499 | ◐ LIKELY ACTIVE |
Universal Stainless & Alloy Products INC | Bridgeville | PA | Primary Metal Manufacturing331110 | — | ◐ LIKELY ACTIVE |