| GAGanaderos Alvarado, INC | Arecibo | PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| GDGoya de Puerto Rico, Inc. | Bayamon | PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| HSHamilton Sundstrand De Puerto Rico, INC. | Santa Isabel | PR | Transportation Equipment Manufacturing336413 | — | ◐ LIKELY ACTIVE |
| HPHewlett Packard | Aguadilla | PR | Computer and Electronic Product Manufacturing334111 | — | ◐ LIKELY ACTIVE |
| HCHubbell Caribe Limited | Vega Baja | PR | Electrical Equipment, Appliance & Component Manufacturing335931 | 500+ | ◐ LIKELY ACTIVE |
| ICIntegra CI, Inc. - Anasco | Anasco | PR | Miscellaneous Manufacturing339112 | 500+ | ◐ LIKELY ACTIVE |
| IPIpr Pharmaceuticals INC | Canovanas | PR | Chemical Manufacturing325412 | 100-499 | ◐ LIKELY ACTIVE |
| JQJaf Quality Services LLC | Coamo | PR | Furniture and Related Product Manufacturing337110 | — | ◐ LIKELY ACTIVE |
| JOJanssen Ortho LLC | Gurabo | PR | Chemical Manufacturing325411 | 500+ | ◐ LIKELY ACTIVE |
| JOJanssen Ortho LLC Ortho Pharmaceutical Div | Manati | PR | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| LOLa Orocovena Biscuit De P.r. INC. | Orocovis | PR | Food Manufacturing311812 | — | ◐ LIKELY ACTIVE |
| LPLaser Products, INC. | Juncos | PR | Chemical Manufacturing325180 | — | ▲ REPORTED CLOSED |
| MCMalegrias, Corporation | Isabela | PR | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| MPMaster Paints & Chemical Corporation | Guayanilla | PR | Chemical Manufacturing325510 | — | ◐ LIKELY ACTIVE |
| MHMcneil Healthcare LLC | Las Piedras | PR | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| MPMedtronic Puerto Rico Operations | Juncos | PR | Computer and Electronic Product Manufacturing334510 | — | ◐ LIKELY ACTIVE |
| MPMedtronic Puerto Rico Operations CO | Juncos | PR | Computer and Electronic Product Manufacturing334510 | — | ◐ LIKELY ACTIVE |
| MGMesser Gas Puerto Rico INC - Cataño | Catano | PR | Chemical Manufacturing325120 | — | ◐ LIKELY ACTIVE |
| MPMinimed Puerto Rico Operations LLC | Juncos | PR | Computer and Electronic Product Manufacturing334510 | — | ◐ LIKELY ACTIVE |
| MDMoretta Diaz, CORP | Adjuntas | PR | Apparel Manufacturing315210 | — | ◐ LIKELY ACTIVE |
| PPPan Pepin INC | Bayamon | PR | Food Manufacturing311812 | — | ◐ LIKELY ACTIVE |
| PPPatheon Puerto Rico INC | Manati | PR | Chemical Manufacturing325412 | 500+ | ◐ LIKELY ACTIVE |
| POPeerless Oil & Chemicals, INC. | Penuelas | PR | Petroleum and Coal Products Manufacturing324110 | 20-99 | ◐ LIKELY ACTIVE |
| PMPentaq Manufacturing CORP | Sabana Grande | PR | Apparel Manufacturing315210 | — | ◐ LIKELY ACTIVE |
| PCPepsico Caribbean CORP | Barceloneta | PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| PPPfizer Pharmaceuticals LLC (vb) | Vega Baja | PR | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| P1Print 1 LLC | Las Piedras | PR | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| PLProductos La Aguadillana INC | Aguadilla | PR | Food Manufacturing311612 | — | ◐ LIKELY ACTIVE |
| PIPropper International INC | Cabo Rojo | PR | Apparel Manufacturing315210 | — | ◐ LIKELY ACTIVE |
| PIPropper International INC | Cabo Rojo | PR | Apparel Manufacturing315210 | — | ◐ LIKELY ACTIVE |
| PFProtego Footwear INC | Cabo Rojo | PR | Apparel Manufacturing315280 | — | ◐ LIKELY ACTIVE |
| PFProtego Footwear, INC | Hatillo | PR | Leather and Allied Product Manufacturing316210 | — | ◐ LIKELY ACTIVE |
| PRPuerto Rico Steel Products CORP | Coto Laurel | PR | Primary Metal Manufacturing331222 | 20-99 | ◐ LIKELY ACTIVE |
| RFRolling & Folding CORP | San German | PR | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| SLSaborea La Lola | Penuelas | PR | Beverage and Tobacco Product Manufacturing312130 | — | ◐ LIKELY ACTIVE |
| SPSchering-plough Products LLC | Las Piedras | PR | Chemical Manufacturing325412 | — | ◐ LIKELY ACTIVE |
| SISteri-tech, INC. | Salinas | PR | Chemical Manufacturing325998 | — | ◐ LIKELY ACTIVE |
| SJSt Jude Medical Puerto Rico LLC | Caguas | PR | Chemical Manufacturing325411 | 100-499 | ◐ LIKELY ACTIVE |
| TPTechno Plastics Industries INC. | Anasco | PR | Plastics and Rubber Products Manufacturing326199 | — | ◐ LIKELY ACTIVE |
| TPTerumo Puerto Rico LLC | Caguas | PR | Miscellaneous Manufacturing339113 | — | ◐ LIKELY ACTIVE |
| TEThermo Electron Puerto Rico INC | Carolina | PR | Machinery Manufacturing333999 | 20-99 | ◐ LIKELY ACTIVE |
| VIVsoske INC. | Vega Baja | PR | Textile Product Mills314110 | 20-99 | ◐ LIKELY ACTIVE |
| BBB Braun of Pr INC | Sabana Grande | PR | Printing and Related Support Activities323111 | — | ◐ LIKELY ACTIVE |
| BABetteroads Asphalt Plt 17 | Caguas | PR | Petroleum and Coal Products Manufacturing324121 | — | ◐ LIKELY ACTIVE |
| BCBorinquen Container | Hatillo | PR | Paper Manufacturing322211 | — | ◐ LIKELY ACTIVE |
| BSBoston Scientific Puerto Rico (fka Guidant Puerto Rico) | Dorado | PR | Computer and Electronic Product Manufacturing334510 | — | ◐ LIKELY ACTIVE |
| CCCaribbean Can Manufacturing | Cidra | PR | Fabricated Metal Product Manufacturing332431 | — | ◐ LIKELY ACTIVE |
| CDCemex De Puerto Rico, INC. | Ponce | PR | Nonmetallic Mineral Product Manufacturing327310 | — | ◐ LIKELY ACTIVE |
| DTDemaco Terminal Operations CORP | Guayanilla | PR | Plastics and Rubber Products Manufacturing326111 | — | ◐ LIKELY ACTIVE |
| EMEcolab Manufacturing INC | Bayamon | PR | Chemical Manufacturing325611 | — | ◐ LIKELY ACTIVE |