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Chemical Manufacturing in California

NAICS 325 · CA

California is home to Chemical Manufacturing, an industry with 2,584 establishments counted by the Bureau of Labor Statistics in 2024. The register lists 5,050 facilities in California as of 2026, with 5 new facilities first seen this year. BIOMARIN PHARMACEUTICAL in Novato had 2,086 employees in 2025.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Biggest counties

Los Angeles1,179San Diego572Orange472Alameda407Santa Clara287San Bernardino271San Mateo266Riverside159

Biggest cities

Plants in California266 FACILITIES

FacilityCityEmployeesStatus
Denali Therapeutics INC.South San Francisco100–499 ACTIVE
Garratt-callahan CompanyBurlingame— ACTIVE
Intersect Ent, INC.Menlo Park— ACTIVE
C S Bio COMenlo Park— ACTIVE
Dompe U.s. INC.San Mateo— ACTIVE
Enable Biosciences INCSouth San Francisco— ACTIVE
Genentech INCSouth San Francisco— ACTIVE
Heirloom Carbon Technologies, INC.Brisbane— ACTIVE
Pylum Biosciences, INC.San Carlos— ACTIVE
Revolution Medicines, INC.Redwood City— ACTIVE
Yenzym Antibodies, LLCBrisbane— ACTIVE
Antheia, INCMenlo Park— ACTIVE
Asegua Therapeutics LLCFoster City— ACTIVE
Baychem, INCMenlo Park— ACTIVE
Coherus Oncology, INC.Redwood City— ACTIVE
Cytokinetics, IncorporatedSouth San Francisco— ACTIVE
Geron CORPFoster City— ACTIVE
Gilead Sciences INCFoster City— ACTIVE
La Canada Ventures INCSan Mateo— ACTIVE
Lamdagen CorporationSan Mateo— ACTIVE
Lifescient, INC.South San Francisco— ACTIVE
Marwell Bio INCSouth San Francisco— ACTIVE
Orca Biosystems, INCMenlo Park— ACTIVE
Oryn Therapeutics, INC.Redwood City— ACTIVE
Zion Health INCSan Mateo— ACTIVE
AstraZeneca Pharmaceutical LP (Redwood City)Redwood City20–99 LIKELY ACTIVE
Cell GenesysS San Francisco— LIKELY ACTIVE
Genentech INC South CampusS San Francisco— LIKELY ACTIVE
Natera INCSan Carlos— LIKELY ACTIVE
Seaport Environmental - RefiningRedwood City— LIKELY ACTIVE
Genentech INC Founders Research Center (mid Campus)South San Francisco— LIKELY ACTIVE
Pliant Therapeutics INC.South San Francisco— LIKELY ACTIVE
Advanced Medicine INCSouth San Francisco— UNVERIFIED
Alza CORP - Evra SiteRedwood City— UNVERIFIED
Applied Biosystems, LLCFoster City— UNVERIFIED
Catalytica Bay View, INC.East Palo Alto— UNVERIFIED
Compound Focus INC Dba Biofocus Dp1South San Francisco— UNVERIFIED
Concrete ChemicalsSan Carlos— UNVERIFIED
Dupont KansaiSouth San Francisco— UNVERIFIED
Peninsula Chemical CO.San Mateo— UNVERIFIED
Romic Environmental Technologies CORPPalo Alto— UNVERIFIED
Silicon Valley Clean WaterRedwood City— UNVERIFIED
Simpson Coatings Group INCSouth San Francisco— UNVERIFIED
Tyco Electronics CorporationMenlo Park— UNVERIFIED
Bioamp Diagnostics INCSan Carlos— LIKELY ACTIVE
BurlingameBurlingame100–499 LIKELY ACTIVE
Carbon Based Fertilizer LLCSan Mateo— LIKELY ACTIVE
Fe Pharmaceuticals INCEmerald Hills— LIKELY ACTIVE
Genentech Usa, INCSouth San Francisco— LIKELY ACTIVE
Geron Corporation - CAFoster City20–99 LIKELY ACTIVE

Search all 5,050 facilities

All chemical manufacturing nationwide · All manufacturing in California