Chemical Manufacturing in California
NAICS 325 · CA
California is home to Chemical Manufacturing, an industry with 2,584 establishments counted by the Bureau of Labor Statistics in 2024. The register lists 5,050 facilities in California as of 2026, with 5 new facilities first seen this year. BIOMARIN PHARMACEUTICAL in Novato had 2,086 employees in 2025.
SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE
Map, cities and product lines
Plants in California5,050 FACILITIES
| Facility | City | Employees | Status |
|---|---|---|---|
| Prodrome Sciences USA LLC | Temecula | — | LIKELY ACTIVE |
| Revance Therapeutics INC | Newark | — | LIKELY ACTIVE |
| Reynolds Systems, INC | Middletown | — | LIKELY ACTIVE |
| Rgf Enterprises INC | Corona | — | LIKELY ACTIVE |
| Royal Adhesives and Sealants, LLC | Wilmington | — | LIKELY ACTIVE |
| Rxd Nova Pharmaceuticals INC. | Vacaville | 1–19 | LIKELY ACTIVE |
| San Diego | San Diego | 1–19 | LIKELY ACTIVE |
| San Joaquin Chemicals, INC. | Fresno | — | LIKELY ACTIVE |
| Scantibodies Laboratory INC | Santee | 20–99 | LIKELY ACTIVE |
| Scargo Labs | Oakland | — | LIKELY ACTIVE |
| Scientific Metal Finishing INC | Santa Clara | 20–99 | LIKELY ACTIVE |
| Sealed Air - Madera | Madera | — | LIKELY ACTIVE |
| Seaport Environmental - Refining | Redwood City | — | LIKELY ACTIVE |
| Searles Valley Minerals INC. | Trona | — | LIKELY ACTIVE |
| Sekisui Diagnostics | San Diego | 100–499 | LIKELY ACTIVE |
| Sekisui Diagnostics LLC | San Diego | — | LIKELY ACTIVE |
| Silver Lake Research CORP | Azusa | — | LIKELY ACTIVE |
| South Kern Industrial Center LLC | Taft | — | LIKELY ACTIVE |
| Spatz Laboratories | Oxnard | 100–499 | LIKELY ACTIVE |
| Sprint Ray | Huntington Beach | — | LIKELY ACTIVE |
| Sprintray, INC. | Los Angeles | — | LIKELY ACTIVE |
| Sunoco LP Stockton Terminal (#1) | Stockton | — | LIKELY ACTIVE |
| Sv Labs | Watsonville | 100–499 | LIKELY ACTIVE |
| Symborg INC. | Selma | — | LIKELY ACTIVE |
| Synergy Health Ast LLC | San Diego | — | LIKELY ACTIVE |
| Targeted Therapy Technologies, LLC | Irvine | — | LIKELY ACTIVE |
| Thang Botanicals INC | Ojai | — | LIKELY ACTIVE |
| The Flamemaster Corporation | Pacoima | — | LIKELY ACTIVE |
| Threshold Enterprises LTD. | Scotts Valley | 100–499 | LIKELY ACTIVE |
| Trademark Cosmetics | Riverside | — | LIKELY ACTIVE |
| True Organic Products - Helm Plant | Helm | 100–499 | LIKELY ACTIVE |
| Tulare Lake Compost | Kettleman City | — | LIKELY ACTIVE |
| US Borax INC | Boron | — | LIKELY ACTIVE |
| Visions Recycling INC. | Azusa | — | LIKELY ACTIVE |
| Vita-Herb Nutriceuticals - Placentia | Placentia | 20–99 | LIKELY ACTIVE |
| Vitrax | Placentia | — | LIKELY ACTIVE |
| Wd-40 Company | San Diego | 100–499 | LIKELY ACTIVE |
| Wood Repair Products INC | Orange | 1–19 | LIKELY ACTIVE |
| Wright Pharma, INC. | Modesto | 20–99 | LIKELY ACTIVE |
| W.R. Meadows of Southern California | Pomona | 20–99 | LIKELY ACTIVE |
| Zeltiq Aesthetics INC | Dublin | — | LIKELY ACTIVE |
| Ablestik Laboratories | Compton | — | LIKELY ACTIVE |
| Advanced Pressure Technology (ap Tech) | Napa | — | LIKELY ACTIVE |
| Air Liquide Large Industries US LP | Rodeo | — | LIKELY ACTIVE |
| Air Products Manufacturing LLC | Paramount | — | LIKELY ACTIVE |
| American International Industries | Los Angeles | — | LIKELY ACTIVE |
| Amgen INC | Thousand Oaks | — | LIKELY ACTIVE |
| Ampac Fine Chemicals | El Dorado Hills | — | LIKELY ACTIVE |
| Auto-chlor System of Oakland | Oakland | — | LIKELY ACTIVE |
| Basf Corporation | Buena Park | — | LIKELY ACTIVE |
All chemical manufacturing nationwide · All manufacturing in California
