| LPLaser Products, INC. | Juncos | — | ▲ REPORTED CLOSED |
| MPMaster Paints & Chemical Corporation | Guayanilla | — | ◐ LIKELY ACTIVE |
| MHMcneil Healthcare LLC | Las Piedras | — | ◐ LIKELY ACTIVE |
| MGMesser Gas Puerto Rico INC - Cataño | Catano | — | ◐ LIKELY ACTIVE |
| PPPatheon Puerto Rico INC | Manati | 500+ | ◐ LIKELY ACTIVE |
| POPeerless Oil & Chemicals, INC. | Penuelas | 20–99 | ◐ LIKELY ACTIVE |
| PPPfizer Pharmaceuticals LLC (vb) | Vega Baja | — | ◐ LIKELY ACTIVE |
| SPSchering-plough Products LLC | Las Piedras | — | ◐ LIKELY ACTIVE |
| SISteri-tech, INC. | Salinas | — | ◐ LIKELY ACTIVE |
| SJSt Jude Medical Puerto Rico LLC | Caguas | 100–499 | ◐ LIKELY ACTIVE |
| EMEcolab Manufacturing INC | Bayamon | — | ◐ LIKELY ACTIVE |
| LDLilly Del Caribe Pr-ii - Lilly Del Caribe Pr-ii | Carolina | — | ◐ LIKELY ACTIVE |
| MIMsd International Gmbh (pr Branch) LLC. | Arecibo | — | ◐ LIKELY ACTIVE |
| AHAbbott Healthcare LTD | Barceloneta | — | ◇ UNVERIFIED |
| APAkzonobel Paints Puerto Rico INC (ici Paints Puerto Rico Inc) | Carolina | — | ◇ UNVERIFIED |
| APApp Pharmaceuticals Manufacturing, LLC | Barceloneta | — | ◇ UNVERIFIED |
| BABasf Agrochemicals Products Bv | Caguas | — | ◇ UNVERIFIED |
| BLBilchem LTD | Ponce | — | ◇ UNVERIFIED |
 Bristol-myers Squibb Manufacturing CO | Barceloneta | — | ◇ UNVERIFIED |
| Bristol-myers Squibb Manufacturing CO. | Mayaguez | — | ◇ UNVERIFIED |
| CHCardinal Health | Humacao | — | ◇ UNVERIFIED |
| CPColgate Palmolive of Puerto Rico INC | Guayama | — | ◇ UNVERIFIED |
| CLCordis LLC | San German | — | ◇ UNVERIFIED |
| EMEnco Manufacturing CORP | Cidra | — | ◇ UNVERIFIED |
| EIEx-lax Incorporated | Humacao | — | ◇ UNVERIFIED |
| FQFlor Quim Incorporated | Patillas | — | ◇ UNVERIFIED |
| FCForto Chemical CORP | Guaynabo | — | ◇ UNVERIFIED |
| GPGalephar Pharmaceutical Research INC | Juncos | — | ◇ UNVERIFIED |
 General Chemical De Puerto Rico INC | Vega Alta | — | ◇ UNVERIFIED |
| GPGk Pharmaceuticals Contract Manufacturing Operations, LLC | Manati | — | ◇ UNVERIFIED |
| HEHeritage Environmental Service Pr LLC | Mayaguez | — | ◇ UNVERIFIED |
| IUInyx USA LTD | Manati | — | ◇ UNVERIFIED |
| IPIpr Pharmaceuticals, Inc./astrazeneca PLC | Canovanas | — | ◇ UNVERIFIED |
| JJJohnson & Johnson Consumer Products | Las Piedras | — | ◇ UNVERIFIED |
| JJJohnson & Johnson Hemisferica Sa | Guaynabo | — | ◇ UNVERIFIED |
| LDLilly Del Caribe (formerly, Ipr) | Guayama | — | ◇ UNVERIFIED |
| MMMarrion Merrell | Manati | — | ◇ UNVERIFIED |
| MPMaster Paints & Chemicals CORP | Guayanilla | — | ◇ UNVERIFIED |
| MCMillipore Cidra INC | Cidra | — | ◇ UNVERIFIED |
| MCMistolin Caribe INC | Bayamon | — | ◇ UNVERIFIED |
| MMMotrin Manufacturing | Barceloneta | — | ◇ UNVERIFIED |
| MIMylan INC | Caguas | — | ◇ UNVERIFIED |
| OLOlay LLC | Cayey | — | ◇ UNVERIFIED |
| PAPan American Fertilizer | Guanica | — | ◇ UNVERIFIED |
| PPPatheon Puerto Rico (form: Mova) | Caguas | — | ◇ UNVERIFIED |
| PPPatheon Puerto Rico INC | Caguas | — | ◇ UNVERIFIED |
| PPPfizer Pharmaceuticals | Guayama | — | ◇ UNVERIFIED |
| PPPfizer Pharmaceuticals - Arecibo | Arecibo | — | ◇ UNVERIFIED |
| PAProductores Avicolas De Pr INC | Salinas | — | ◇ UNVERIFIED |
| TPTapi Puerto Rico INC | Guayama | — | ◇ UNVERIFIED |
