| EMEnco Manufacturing CORP | Cidra | — | ◇ UNVERIFIED |
| EIEx-lax Incorporated | Humacao | — | ◇ UNVERIFIED |
| FQFlor Quim Incorporated | Patillas | — | ◇ UNVERIFIED |
| FCForto Chemical CORP | Guaynabo | — | ◇ UNVERIFIED |
| GPGalephar Pharmaceutical Research INC | Juncos | — | ◇ UNVERIFIED |
 General Chemical De Puerto Rico INC | Vega Alta | — | ◇ UNVERIFIED |
| GPGk Pharmaceuticals Contract Manufacturing Operations, LLC | Manati | — | ◇ UNVERIFIED |
| HEHeritage Environmental Service Pr LLC | Mayaguez | — | ◇ UNVERIFIED |
| IUInyx USA LTD | Manati | — | ◇ UNVERIFIED |
| IPIpr Pharmaceuticals, Inc./astrazeneca PLC | Canovanas | — | ◇ UNVERIFIED |
| JJJohnson & Johnson Consumer Products | Las Piedras | — | ◇ UNVERIFIED |
| JJJohnson & Johnson Hemisferica Sa | Guaynabo | — | ◇ UNVERIFIED |
| LDLilly Del Caribe (formerly, Ipr) | Guayama | — | ◇ UNVERIFIED |
| MMMarrion Merrell | Manati | — | ◇ UNVERIFIED |
| MCMillipore Cidra INC | Cidra | — | ◇ UNVERIFIED |
| MCMistolin Caribe INC | Bayamon | — | ◇ UNVERIFIED |
| MIMylan INC | Caguas | — | ◇ UNVERIFIED |
| OLOlay LLC | Cayey | — | ◇ UNVERIFIED |
| PAPan American Fertilizer | Guanica | — | ◇ UNVERIFIED |
| PPPatheon Puerto Rico (form: Mova) | Caguas | — | ◇ UNVERIFIED |
| PPPatheon Puerto Rico INC | Caguas | — | ◇ UNVERIFIED |
| PPPfizer Pharmaceuticals | Guayama | — | ◇ UNVERIFIED |
| PPPfizer Pharmaceuticals - Arecibo | Arecibo | — | ◇ UNVERIFIED |
| PAProductores Avicolas De Pr INC | Salinas | — | ◇ UNVERIFIED |
| TPTapi Puerto Rico INC | Guayama | — | ◇ UNVERIFIED |
| URUcar Resinas Caribe INC. | Bayamon | — | ◇ UNVERIFIED |
| WCWarner Chilcott Company LLC | Fajardo | — | ◇ UNVERIFIED |
| WLWyeth-ayerst Lederle | Carolina | — | ◇ UNVERIFIED |
| AAAbbVie - APL | Barceloneta | 100–499 | ◐ LIKELY ACTIVE |
| BABASF Agricultural Products de PR | Manati | 100–499 | ◐ LIKELY ACTIVE |
| BGBaxter Guayama | Guayama | 100–499 | ◐ LIKELY ACTIVE |
| BIBoehringer Ingelheim Animal Health Puerto Rico LLC | Barceloneta | 100–499 | ◐ LIKELY ACTIVE |
 Bristol-Myers Squibb - Puerto Rico Guaynabo | Guaynabo | 20–99 | ◐ LIKELY ACTIVE |
| CPCatano, PR | Catano | 20–99 | ◐ LIKELY ACTIVE |
| CCClorox Cleaning Products | Caguas | 20–99 | ◐ LIKELY ACTIVE |
| DPDorado Plant | Dorado | 20–99 | ◐ LIKELY ACTIVE |
| JCJanssen Cilag | Gurabo | 100–499 | ◐ LIKELY ACTIVE |
| LDLilly Del Carbe Inc Carolina | Carolina | 500+ | ◐ LIKELY ACTIVE |
| OBOrtho Biologics LLC | Manati | 20–99 | ◐ LIKELY ACTIVE |
| PAPan American Grain Company-fertilizer | Guanica | 20–99 | ◐ LIKELY ACTIVE |
| PCPF Consumer Healthcare B.V.(Puerto Rico Operations) LLC | Guayama | 500+ | ◐ LIKELY ACTIVE |
| PBPfizer Barceloneta / Viatris Pharmaceuticals, LLC. | Barceloneta | 100–499 | ◐ LIKELY ACTIVE |
| PPPfizer Pharmaceuticals LLC / Viatris - Barceloneta | Barceloneta | 100–499 | ◐ LIKELY ACTIVE |
| PPPfizer Pharmaceuticals LLC / Viatris - Vega Baja | Vega Baja | 500+ | ◐ LIKELY ACTIVE |
| IMIcb Manufacturing Co, INC. | Carolina | 20–99 | ◇ UNVERIFIED |
