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Chemical Manufacturing in South Carolina

NAICS 325 · SC

The Chemical Manufacturing industry in South Carolina had 836 establishments, according to the Bureau of Labor Statistics in 2025. This register lists 481 facilities in South Carolina. Nephron Pharmaceutical, located in West Columbia Sc, employed 984 people in 2025.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines

Biggest counties

Greenville78Spartanburg62York43Richland31Berkeley27Charleston25Aiken20Anderson15

Biggest cities

Plants in South Carolina53 FACILITIES

Listing 53 of 78: the facilities with a website, a size band or two sources on record. The rest are in site search.

FacilityCityEmployeesStatus
Hentzen Coatings INCGreenville20–99 ACTIVE
Southern Water Treatment CO INCGreenville1–19 ACTIVE
Zylo Therapeutics, INC.Greenville1–19 ACTIVE
Alexium, INCGreer— ACTIVE
Clayens US Holding INCGreenville— ACTIVE
Mag It LLCSimpsonville— ACTIVE
Pai Holdings, LLCGreenville— ACTIVE
Rockit Pest INC.Greenville— ACTIVE
Cpj TechnologiesTaylors20–99 LIKELY ACTIVE
Pioneer ChemicalGreenville1–19 LIKELY ACTIVE
Span Packaging Services LLC Dba MultipacGreenville100–499 LIKELY ACTIVE
Ashland INC.Piedmont— LIKELY ACTIVE
ChromascapeGreenville— LIKELY ACTIVE
Diversified Coating Systems INCGreenville— LIKELY ACTIVE
Irix Manufacturing IncorporatedGreenville— LIKELY ACTIVE
Mitsubishi Chemical America, Performance PolymersGreer20–99 LIKELY ACTIVE
Syensqo Specialty Polymers Usa, LLCGreenville— LIKELY ACTIVE
Cognis Corporation/mauldin, Sc Manufacturing PlantMauldin— LIKELY ACTIVE
Ethox Chemicals LLC.Greenville— LIKELY ACTIVE
General Nutrition Products IncorporatedGreenville— LIKELY ACTIVE
Holly Oak ChemicalFountain Inn— LIKELY ACTIVE
Metal Chem INCGreenville— LIKELY ACTIVE
Ortec Clean Room AdditionPiedmont— LIKELY ACTIVE
Perrigo CompanyGreenville— LIKELY ACTIVE
Royal Adhesives & Sealants, LLCSimpsonville— LIKELY ACTIVE
Aiken Chemical CO INC.Greer20–99 LIKELY ACTIVE
Chemgard, INCGreer1–19 LIKELY ACTIVE
Pl Developments LLCPiedmont— LIKELY ACTIVE
Purple PowerGreer20–99 LIKELY ACTIVE
Reynolds CompanyGreenville100–499 LIKELY ACTIVE
Holly Oak Chemical IncFountain Inn20–99 LIKELY ACTIVE
Hoechst Celanese:greenvilleGreenville1–19 UNVERIFIED
International Vitamin CorporationGreenville— LIKELY ACTIVE
Pharmaceutical Associates IncorporatedGreenville— LIKELY ACTIVE
Crucible Chemical - ClosedGreenville— LIKELY ACTIVE
Janed Enterprises INCTaylors1–19 LIKELY ACTIVE
Nicca USA INCFountain Inn— LIKELY ACTIVE
Pharmaceutical Associates INCGreenville,— LIKELY ACTIVE
Qualflex Technologies, LLCGreenville20–99 LIKELY ACTIVE
Ashland Chemical Company GreenvilleGreenville— UNVERIFIED
Bausch & Lomb Greenville Solutions FacilityGreenville— UNVERIFIED
Bostik INCGreenville— UNVERIFIED
Evrnu Sc Research FacilityGreer— UNVERIFIED
First Source Worldwide LLCGreenville— UNVERIFIED
Kl - ChempakGreenville— UNVERIFIED
Metal Chem INCGreer— UNVERIFIED
New Life Chemical Sodium Hydrosulfite LLCGreenville— UNVERIFIED
Nippon Carbide IndustriesGreenville— UNVERIFIED
Siroflex Site ImprovementsGreenville— UNVERIFIED
Span Packaging Services LLCGreenville— UNVERIFIED

Search all 481 facilities

All chemical manufacturing nationwide · All manufacturing in South Carolina