| FQFirst Quality Tissue Southeast | Anderson | 500+ | ◐ LIKELY ACTIVE |
| G2Grh 2011 LLC | Rock Hill | — | ◐ LIKELY ACTIVE |
| HIHahl INC | Lexington | 20–99 | ◐ LIKELY ACTIVE |
| ICIngevity Corporation Technical and Innovation Center | Charleston | — | ◐ LIKELY ACTIVE |
| IVInternational Vitamin Corporation | Greenville | — | ◐ LIKELY ACTIVE |
| LILife Industries CORP | N Charleston | — | ◐ LIKELY ACTIVE |
| MTMatheson Tri-gas Inc/spartanburg-brooks | Spartanburg | — | ◐ LIKELY ACTIVE |
| MCMitsubishi Chemical America, Performance Polymers | Greer | 20–99 | ◐ LIKELY ACTIVE |
| NSNational Starch and Chemical Company | Enoree | — | ◐ LIKELY ACTIVE |
| NUNutricia USA | Anderson | — | ◐ LIKELY ACTIVE |
| OPOakwood Products Inc. | Estill | 20–99 | ◐ LIKELY ACTIVE |
Organic Dyes and Pigments | Union | 1–19 | ◐ LIKELY ACTIVE |
| OPOrion Performance Compounds, INC. | Lugoff | — | ◐ LIKELY ACTIVE |
| PAPharmaceutical Associates INC | Greenville | — | ◐ LIKELY ACTIVE |
| PAPharmaceutical Associates Incorporated | Greenville | — | ◐ LIKELY ACTIVE |
| PDPiedmont Dielectrics Corporation | Woodruff | — | ◐ LIKELY ACTIVE |
| PCPioneer Chemical | Greenville | — | ◐ LIKELY ACTIVE |
| PDPl Developments LLC | Piedmont | — | ◐ LIKELY ACTIVE |
| PPPolymer Processing Inc | Rock Hill | 20–99 | ◐ LIKELY ACTIVE |
| PPProtech Powder Coatings INC | Spartanburg | — | ◐ LIKELY ACTIVE |
| RCRe:build Cr, LLC | Rock Hill | — | ◐ LIKELY ACTIVE |
| SMSantolubes Manufacturing LLC | Spartanburg | 20–99 | ◐ LIKELY ACTIVE |
| SISiegwerk Ink Packaging | Boiling Springs | — | ◐ LIKELY ACTIVE |
Signode Industrial Group-Latta | Latta | 20–99 | ◐ LIKELY ACTIVE |
| SGSi Group INC Orangeburg | Orangeburg | — | ◐ LIKELY ACTIVE |
| SPSpan Packaging Services LLC Dba Multipack Solutions | Greenville | — | ◐ LIKELY ACTIVE |
| UFUS Fibers | Trenton | 100–499 | ◐ LIKELY ACTIVE |
| VUValagro USA Manufacturing | Orangeburg | 1–19 | ◐ LIKELY ACTIVE |
| WCWikoff Color CORP | Fort Mill | — | ◐ LIKELY ACTIVE |
| AIAaron Industries | Clinton | — | ◐ LIKELY ACTIVE |
| ACAiken Chemical CO INC. | Greer | — | ◐ LIKELY ACTIVE |
| BCBayer CORP Rock Hill Plant | Rock Hill | — | ◐ LIKELY ACTIVE |
| CMCapsugel Manufacturing INC | Greenwood | — | ◐ LIKELY ACTIVE |
| CLClariant Lsm America Incorporated Lugoff | Lugoff | — | ◐ LIKELY ACTIVE |
| CCCrucible Chemical - Closed | Greenville | — | ◐ LIKELY ACTIVE |
| FBFirestone Buliding Products CO | Kingstree | — | ◐ LIKELY ACTIVE |
| GSGeochem Solutions, INC | Duncan | — | ◐ LIKELY ACTIVE |
| GCGlassmaster CO Monofilament Division | Lexington | — | ◐ LIKELY ACTIVE |
| ICInbra Chemical Company INC | Orangeburg | — | ◐ LIKELY ACTIVE |
| NUNicca USA INC | Fountain Inn | — | ◐ LIKELY ACTIVE |
Pacific Industrial Development Corporation | Spartanburg | — | ◐ LIKELY ACTIVE |
| PEPolyquest East Site Expansion Phase 2 Build Out | Darlington | — | ◐ LIKELY ACTIVE |
| RCReynolds Chemical:greenville | Greenville | — | ◐ LIKELY ACTIVE |
| SRSentury Reagents INC. | Rock Hill | — | ◐ LIKELY ACTIVE |
| SMSpecialty Minerals INC | Eastover | — | ◐ LIKELY ACTIVE |
| ZLZf Lemforder CORP Heavy Truck Div | Lancaster | — | ◐ LIKELY ACTIVE |
| AEAdvanced Environmental Options INC | Spartanburg | — | ◇ UNVERIFIED |
| AUAgrium US INC | Hartsville | — | ◇ UNVERIFIED |
| ACAlbemarle Corporation | Orangeburg | — | ◇ UNVERIFIED |
| APAlpek Polyester Usa, LLC | Moncks Corner | — | ◇ UNVERIFIED |