Chemical Manufacturing in South Carolina
NAICS 325 · SC
The Chemical Manufacturing industry in South Carolina had 836 establishments, according to the Bureau of Labor Statistics in 2025. This register lists 481 facilities in South Carolina. Nephron Pharmaceutical, located in West Columbia Sc, employed 984 people in 2025.
SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE
Map, cities and product lines
Plants in South Carolina345 FACILITIES
Listing 345 of 481: the facilities with a website, a size band or two sources on record. The rest are in site search.
| Facility | City | Employees | Status |
|---|---|---|---|
| Gaf | Charleston | — | UNVERIFIED |
| Hemmelrath Coatings INC | Duncan | — | UNVERIFIED |
| Ineos US Chemicals Company | Wando | — | UNVERIFIED |
| Innophos LLC | Green Pond | — | UNVERIFIED |
| Kl - Chempak | Greenville | — | UNVERIFIED |
| Kuraray America INC Vectran Divison | Fort Mill | — | UNVERIFIED |
| Leiner Health Products | Fort Mill | — | UNVERIFIED |
| Lgc Standards/o2si Smart Solutions | North Charleston | — | UNVERIFIED |
| Linde Gas | Blythewood | — | UNVERIFIED |
| Matrix Scientific | Pontiac | — | UNVERIFIED |
| Metal Chem INC | Greer | — | UNVERIFIED |
| Milliken Chemical Keystone Plant- Milli | Inman | — | UNVERIFIED |
| New Life Chemical Sodium Hydrosulfite LLC | Greenville | — | UNVERIFIED |
| Nippon Carbide Industries | Greenville | — | UNVERIFIED |
| Ohio Gratings INC | Ridgeland | — | UNVERIFIED |
| Pirelli Cable and Systems LLC | West Columbia | — | UNVERIFIED |
| Renew Resources LLC | Rock Hill | — | UNVERIFIED |
| Rose Talbert Paint Company | Cayce | — | UNVERIFIED |
| Rudolf-venture Chemicals | Rock Hill | — | UNVERIFIED |
| Samuel, Son &co (usa) INC. - Samuel Packaging Systems Group | Fort Mill | — | UNVERIFIED |
| Sherwin Williams Spartanburg | Spartanburg | — | UNVERIFIED |
| Siroflex Site Improvements | Greenville | — | UNVERIFIED |
| South Eastern Recycling Solutions | Rock Hill | — | UNVERIFIED |
| Span Packaging Services LLC | Greenville | — | UNVERIFIED |
| Springs Ind Wamchem Npl Site | Burton | — | UNVERIFIED |
| Swisher Hygiene | Irmo | — | UNVERIFIED |
| Swisher Hygiene | Charleston | — | UNVERIFIED |
| Wolverine Coatings CORP | Spartanburg | — | UNVERIFIED |
| 027116-associates Onsite - Colgate - Hodges Sc | Hodges | 20–99 | LIKELY ACTIVE |
| 872 Camden | Lugoff | 20–99 | LIKELY ACTIVE |
| Agfa Materials - Bushy Park | Goose Creek | 20–99 | LIKELY ACTIVE |
| AguaSeal | North Charleston | 1–19 | LIKELY ACTIVE |
| Aiken | Aiken | 20–99 | LIKELY ACTIVE |
| AmbioPharm, Inc. | North Augusta | 100–499 | LIKELY ACTIVE |
| Andy Oxy CO INC Taylors | Taylors | 1–19 | LIKELY ACTIVE |
| BASF Clemson | Centra | 20–99 | LIKELY ACTIVE |
| BASF Mauldin | Mauldin | 20–99 | LIKELY ACTIVE |
| Bees Ferry | Charelston | 1–19 | LIKELY ACTIVE |
| Charleston SC IW Plant | North Charleston | 20–99 | LIKELY ACTIVE |
| Columbia Branch 61 | Columbia | 1–19 | LIKELY ACTIVE |
| Contec, INC. - Flatwood | Spartanburg | 20–99 | LIKELY ACTIVE |
| Contec, INC. - Wingo Park | Spartanburg | 100–499 | LIKELY ACTIVE |
| C&S Chemicals - Darlington, SC | Darlington | 20–99 | LIKELY ACTIVE |
| C&S Chemicals - Hardeeville, SC | Hardeeville | 1–19 | LIKELY ACTIVE |
| Darlington | Darlington | 100–499 | LIKELY ACTIVE |
| Denise Quarles | Florence | — | REPORTED CLOSED |
| Diatom US | Andrews | 20–99 | LIKELY ACTIVE |
| DuPont Cooper River | Moncks Corner | 20–99 | LIKELY ACTIVE |
| Esp | Laurens | 20–99 | LIKELY ACTIVE |
| Exco East LLC | Conway | — | LIKELY ACTIVE |
All chemical manufacturing nationwide · All manufacturing in South Carolina