Chemical Manufacturing in South Dakota
NAICS 325 · SD
Chemical Manufacturing is an industry in South Dakota. The Bureau of Labor Statistics counted 37 establishments in South Dakota in 2025. This register lists 63 facilities in South Dakota.
SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE
Map, cities and product lines
Plants in South Dakota4 FACILITIES
| Facility | City | Employees | Status |
|---|---|---|---|
| Vst LLC | Brookings | — | ACTIVE |
| Valero Renewable Fuels Company | Aurora | — | LIKELY ACTIVE |
| Medgene | Brookings | 100–499 | LIKELY ACTIVE |
| Valero Renewable Fuels Company, LLC dba Valero Aurora Plant | Aurora | 20–99 | LIKELY ACTIVE |
All chemical manufacturing nationwide · All manufacturing in South Dakota