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Chemical Manufacturing

27,897 FACILITIESAll Census product lines →

NAICS 325

The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.

SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE

Map, cities and product lines
Map of United States manufacturing facilities

Plants in this industry27,897 FACILITIES

FacilityCityStateEmployeesStatus
Nyco America LLCNewnanGA20–99 ACTIVE
Nyco Products COCountrysideIL20–99 ACTIVE
Nylon Corporation of AmericaManchesterNH20–99 ACTIVE
Occidental Chemical Corporation - Muscle Shoals PlantMuscle ShoalsAL20–99 ACTIVE
Occidental Chemical Corporation - Wichita PlantWichitaKS100–499 ACTIVE
Ocular Therapeutix, INCBedfordMA100–499 ACTIVE
Ocusoft INC.RosenbergTX20–99 ACTIVE
Olin Chlor-alkali, Charleston PlantCharlestonTN100–499 ACTIVE
Olin CORP. Mcintosh, Alabama PlantMcintoshAL100–499 ACTIVE
Omega Bio-tek, INC.NorcrossGA— ACTIVE
Omniguide, INCBillericaMA— ACTIVE
Ony Biotech INCAmherstNY20–99 ACTIVE
Optima Chemical Group LLCDouglasGA100–499 ACTIVE
Opti Medical Systems INCRoswellGA100–499 ACTIVE
Optimum Technologies, INC.CartersvilleGA20–99 ACTIVE
Orasure Technologies INCBethlehemPA100–499 ACTIVE
Organic Dyes and Pigments, LLCLincolnRI20–99 ACTIVE
Organic Standard Solutions International LLCNorth CharlestonSC20–99 ACTIVE
Organogenesis INCCantonMA— ACTIVE
Orion Engineered CarbonsBelpreOH20–99 ACTIVE
Orion Engineered Carbons Borger PlantBorgerTX20–99 ACTIVE
Ortec:easleyEasleySC100–499 ACTIVE
Owen Oil Tools LPGodleyTX100–499 ACTIVE
Oxarc INC PascoPascoWA20–99 ACTIVE
Oxford Performance Materials, INC.South WindsorCT20–99 ACTIVE
Pacific Scientific Energetic Materials CO California LLCChandlerAZ100–499 ACTIVE
Pacific Scientific Energetic Materials Company (california Llc)HollisterCA— ACTIVE
Pari Respiratory Equipment, INC.MidlothianVA20–99 ACTIVE
Patheon Manufacturing Services LLCGreenvilleNC500+ ACTIVE
Pbi Performance Products INCRock HillSC20–99 ACTIVE
Pecora CORPHarleysvillePA20–99 ACTIVE
Pel-freez, LLCRogersAR— ACTIVE
Pennsylvania Grain Processing LLCClearfieldPA20–99 ACTIVE
Perimeter Solutions LPGreen BayWI— ACTIVE
Perrigo Holland INCHollandMI100–499 ACTIVE
Pharmaceutics International INCHunt ValleyMD100–499 ACTIVE
Phibro Tech INCSanta Fe SpringsCA20–99 ACTIVE
Photronics Idaho, INC.BoiseID100–499 ACTIVE
Photronics INCBrookfieldCT100–499 ACTIVE
Photronics Texas Allen, INC.AllenTX100–499 ACTIVE
Phytogenx, INCMorgantownPA100–499 ACTIVE
Pilot Chemical CO Middletown Ohio FacilityMiddletownOH20–99 ACTIVE
Piramal Critical Care INCBethlehemPA100–499 ACTIVE
Piramal Pharma Solutions INCLexingtonKY100–499 ACTIVE
Placid Refining Company LLCPort AllenLA100–499 ACTIVE
Plainview Bioenergy, LLCPlainviewTX20–99 ACTIVE
Plascore INCZeelandMI— ACTIVE
Plaskolite INCZanesvilleOH100–499 ACTIVE
Plaskolite, LLC.ColumbusOH100–499 ACTIVE
Plastikon HealthcareLawrenceKS100–499 ACTIVE

Search all 27,897 facilities

Common questions

How many chemical manufacturing facilities are in the United States?

As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.

Which state has the most chemical manufacturing facilities?

California, with 5,100 facilities listed.

How many chemical manufacturing facilities are still operating?

14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.