Chemical Manufacturing
27,897 FACILITIESAll Census product lines →NAICS 325
The Chemical Manufacturing industry, as defined by NAICS 325, had an annual payroll of about $110.1 billion according to the Bureau of Labor Statistics in 2025. The Bureau of Labor Statistics counted 25801 establishments in the Chemical Manufacturing industry across the United States in 2025. This register lists 27897 facilities in total.
SUMMARIZED FROM THE FEDERAL FIGURES ON THIS PAGE
Map, cities and product lines
Top cities
Product lines reported here
These are counts by industry: the Economic Census records what establishments in chemical manufacturing reported producing, and never names a plant.
Plants in this industry27,897 FACILITIES
| Facility | City | State | Employees | Status |
|---|---|---|---|---|
| Questvapco Corporation | Brenham | TX | 100–499 | ACTIVE |
| Quicksilver Scientific | Louisville | CO | 100–499 | ACTIVE |
| Rainbow Fertilizer LLC | Americus | GA | 20–99 | ACTIVE |
| Rec Advanced Silicon Materials LLC | Butte | MT | 100–499 | ACTIVE |
| R.e. Darling Co., INC. | Tucson | AZ | 100–499 | ACTIVE |
| Redfield Energy, LLC | Redfield | SD | 20–99 | ACTIVE |
| Red River Energy LLC | Rosholt | SD | 20–99 | ACTIVE |
| Red Spot Paint & Varnish Company INC | Evansville | IN | 100–499 | ACTIVE |
| Regal Chemical Company | Alpharetta | GA | 20–99 | ACTIVE |
| Reg Geismar, LLC | Geismar | LA | 100–499 | ACTIVE |
| Regis Technologies INC | Morton Grove | IL | 20–99 | ACTIVE |
| Reinhold Industries INC | Santa Fe Springs | CA | — | ACTIVE |
| Resinall Mississippi - Hattiesburg | Hattiesburg | MS | 100–499 | ACTIVE |
| Reynolds Polymer Technology, INC. | Grand Junction | CO | 20–99 | ACTIVE |
| Rhodia, Baytown Plant | Baytown | TX | 20–99 | ACTIVE |
| Ricca Chemical | Arlington | TX | 20–99 | ACTIVE |
| Richard-allan Scientific LLC | Kalamazoo | MI | — | ACTIVE |
| Rimtec Corporation | Burlington Twp | NJ | 20–99 | ACTIVE |
| Ringneck Energy, LLC | Onida | SD | 20–99 | ACTIVE |
| Ritedose CORP | Columbia | SC | 500+ | ACTIVE |
| Rochester Midland Corporation | Rochester | NY | — | ACTIVE |
| Rocky Mountain Reagents, INC. | Golden | CO | 20–99 | ACTIVE |
| Rogers Corporation | Woodstock | CT | 100–499 | ACTIVE |
| Rogers Corporation | Chandler | AZ | 100–499 | ACTIVE |
| Rohm and Haas Chemicals Bayport | La Porte | TX | 100–499 | ACTIVE |
| Ronald Mark Associates INC | Hillside | NJ | — | ACTIVE |
| Royal Chemical CO * | Macedonia | OH | — | ACTIVE |
| R. Stresau Laboratory, INC. | Spooner | WI | 20–99 | ACTIVE |
| Rust-oleum | Attleboro | MA | 20–99 | ACTIVE |
| Rust-oleum | Waupun | WI | 20–99 | ACTIVE |
| Rust-oleum Corporation | Somerset | NJ | 20–99 | ACTIVE |
| Sabic Innovative Plastics US LLC | Ottawa | IL | 100–499 | ACTIVE |
| Saint-gobain Performance Plastics Corporation | Bristol | RI | 100–499 | ACTIVE |
| Sandstrom Products Company | Port Byron | IL | 20–99 | ACTIVE |
| Sanofi | Ridgefield | NJ | 100–499 | ACTIVE |
| Sapona Plastics, LLC | Asheboro | NC | 100–499 | ACTIVE |
| Sasol Chemicals - Greens Bayou Plant | Houston | TX | 20–99 | ACTIVE |
| Sauereisen INC | Pittsburgh | PA | 20–99 | ACTIVE |
| Schwaab INC | Brookfield | WI | 100–499 | ACTIVE |
| Sciegen Pharmaceuticals INC | Hauppauge | NY | 100–499 | ACTIVE |
| Sc Johnson Professional | Stanley | NC | 20–99 | ACTIVE |
| Seacole-crc, LLC | Plymouth | MN | — | ACTIVE |
| Sealed Air CORP - Danbury | Danbury | CT | 20–99 | ACTIVE |
| Seatex - Pasadena | Pasadena | TX | 20–99 | ACTIVE |
| Security Signals, INC. | Cordova | TN | 20–99 | ACTIVE |
| Seemann Composites, LLC | Gulfport | MS | 100–499 | ACTIVE |
| Sentio Biosciences LLC | Maryland Heights | MO | 20–99 | ACTIVE |
| Sentry Industries INC | Miami | FL | 20–99 | ACTIVE |
| Seqirus INC | Holly Springs | NC | — | ACTIVE |
| Shakespeare Company, LLC | Columbia | SC | 100–499 | ACTIVE |
Common questions
How many chemical manufacturing facilities are in the United States?
As of SEP 2026, FactoryRegistry lists 27,897 chemical manufacturing facilities (NAICS 325) across 55 states, compiled from EPA, OSHA and Census records.
Which state has the most chemical manufacturing facilities?
California, with 5,100 facilities listed.
How many chemical manufacturing facilities are still operating?
14,382 of the 27,897 listed carry a recent operating signal in federal data — the register's Active or Likely active status. The rest are listed from their filings alone, which is a gap in the federal record rather than evidence that a plant has closed.

